公开(公告)号：US20160089541A1

公开(公告)日：2016-03-31

申请号：US14869487

申请日：2015-09-29

Applicant: Advanced Neuromodulation Systems, Inc. dba St. Jude Neuromodulation Division

Inventor： Lalit Venkatesan

IPC: A61N1/36 ,  A61N1/05

CPC classification number: A61N1/36185 ,  A61N1/0529 ,  A61N1/36067 ,  A61N1/36178

Abstract: In one embodiment, a neurostimulation system for stimulating neuronal tissue of a brain of a patient, comprises: an implantable pulse generator comprising pulse generating circuitry and a controller; one or more stimulation leads comprising multiple electrodes, the implantable pulse generator adapted to connect to the one or more stimulation leads for delivery of generated electrical pulses to neuronal tissue of the patient; wherein the controller is adapted to control the implantable pulse generator to (i) generate a plurality of bursts of multiple pulses at a frequency of at least 100 Hz and (ii) to deliver each respective bursts on a randomly or pseudo-randomly selected electrode from multiple electrodes of the one or more stimulation leads, wherein a beginning of each burst in the plurality of bursts is separated from a beginning of its respective successive bursts by at least 50 milliseconds.

Abstract translation: 在一个实施例中，用于刺激患者的脑的神经元组织的神经刺激系统包括：包括脉冲发生电路和控制器的可植入脉冲发生器; 一个或多个刺激引线包括多个电极，所述可植入脉冲发生器适于连接到所述一个或多个刺激引线，用于将产生的电脉冲传送到患者的神经元组织; 其中所述控制器适于控制所述可植入脉冲发生器以（i）以至少100Hz的频率产生多个脉冲的突发，以及（ii）将随机或伪随机选择的电极上的每个相应的脉冲串从 所述一个或多个刺激引线的多个电极，其中所述多个脉冲串中的每个脉冲串的开始与其相应的连续脉冲串的开始相隔至少50毫秒。

公开(公告)号：US20250099765A1

公开(公告)日：2025-03-27

申请号：US18644067

申请日：2024-04-23

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Filippo Agnesi ,  Lalit Venkatesan ,  Christopher S. L. Crawford

IPC: A61N1/36 ,  A61N1/06 ,  A61N1/372

Abstract: This application is generally related to identifying or otherwise programming one or more cycling parameters for operation of an implantable pulse generator to provide a neurostimulation therapy to a patient using a non-paresthesia stimulation pattern. In some embodiments, the cycling parameter is selected by measuring physiological signals during trial stimulation. In other embodiments, multiple cycling parameters are identified for use by the patient using a patient controller device.

公开(公告)号：US11964152B2

公开(公告)日：2024-04-23

申请号：US16404517

申请日：2019-05-06

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Filippo Agnesi ,  Lalit Venkatesan ,  Christopher S. L. Crawford

IPC: A61N1/06 ,  A61N1/36 ,  A61N1/372

CPC classification number: A61N1/36071 ,  A61N1/06 ,  A61N1/36062 ,  A61N1/36167 ,  A61N1/37247

Abstract: This application is generally related to identifying or otherwise programming one or more cycling parameters for operation of an implantable pulse generator to provide a neurostimulation therapy to a patient using a non-paresthesia stimulation pattern. In some embodiments, the cycling parameter is selected by measuring physiological signals during trial stimulation. In other embodiments, multiple cycling parameters are identified for use by the patient using a patient controller device.