专利检索 ap:("Advaxis, Inc." OR "The Trustees of the University of Pennsylvania") AND inv:"VAFA SHAHABI" 第 1 页

1.

发明申请
COMPOSITIONS AND METHODS COMPRISING KLK3 OR FOLH1 ANTIGEN 有权
标题翻译：包含KLK3或FOLH1抗原的组合物和方法

公开(公告)号：US20150335721A1

公开(公告)日：2015-11-26

申请号：US14581217

申请日：2014-12-23

申请人： The Trustees of the University of Pennsylvania , Advaxis, Inc.

发明人： YVONNE PATERSON , JOHN ROTHMAN , VAFA SHAHABI

IPC分类号： A61K39/00 , C07K14/195 , C12N9/64

CPC分类号： A61K39/0011 , A61K39/02 , A61K2039/523 , A61K2039/53 , C07K14/195 , C07K2319/00 , C07K2319/40 , C12N9/485 , C12N9/6445 , C12Y304/17021 , C12Y304/21077

摘要： The present invention provides KLK3 peptides, FOLH1 peptides, recombinant polypeptides comprising same, recombinant nucleotide molecules encoding same, recombinant Listeria strains comprising same, and immunogenic and therapeutic methods utilizing same.

摘要翻译： 本发明提供KLK3肽，FOLH1肽，包含其的重组多肽，编码其的重组核苷酸分子，包含其的重组利斯特氏菌菌株，以及利用其的免疫原性和治疗方法。

2.

发明申请
COMPOSITIONS AND METHODS FOR PREVENTION OF ESCAPE MUTATION IN THE TREATMENT OF HER2/NEU OVER-EXPRESSING TUMORS 审中-公开
标题翻译：用于预防HER2 / NEU过度表达肿瘤的ESCAPE突变的组合物和方法

公开(公告)号：US20150297702A1

公开(公告)日：2015-10-22

申请号：US14788936

申请日：2015-07-01

申请人： Advaxis, Inc. , The Trustees of the University of Pennsylvania

发明人： VAFA SHAHABI , ANU WALLECHA , PAULO C. MACIAG , YVONNE PATERSON , MATTHEW SEAVEY , NICOLA MASON

IPC分类号： A61K39/02 , A61K35/742

CPC分类号： A61K39/0208 , A61K35/74 , A61K35/742 , A61K38/193 , A61K39/0011 , A61K2039/52 , A61K2039/523 , A61K2039/552 , A61K2039/585 , A61K2039/6037 , A61K2300/00

摘要： This invention provides compositions and methods for treating and vaccinating against a Her2/neu antigen-expressing tumor and inducing an immune response against dominant in a human subject.

摘要翻译： 本发明提供用于治疗和接种针对Her2 / neu抗原表达的肿瘤并在人受试者中诱导针对显性的免疫应答的组合物和方法。

3.

发明申请
COMPOSITIONS AND METHODS FOR PREVENTION OF ESCAPE MUTATION IN THE TREATMENT OF HER2/NEU OVER-EXPRESSING TUMORS 审中-公开

公开(公告)号：US20150238584A1

公开(公告)日：2015-08-27

申请号：US14189008

申请日：2014-02-25

申请人： Advaxis, Inc. , The Trustees of the University of Pennsylvania

发明人： VAFA SHAHABI , Anu Wallecha , Paulo C. Maciag , Yvonne Paterson , Nicola Mason , Matthew M. Seavey

IPC分类号： A61K39/00

CPC分类号： A61K39/0011 , A61K2039/522 , A61K2039/523 , A61K2039/545 , A61K2039/55 , A61K2039/552 , A61K2039/572 , C07K14/195 , C07K14/82 , C07K2319/40 , C12N1/20 , C12N1/36 , C12N9/12 , C12N9/90 , C12N15/74 , C12Y207/10 , C12Y501/01001

摘要： This invention provides compositions and methods for treating and vaccinating against a Her2/neu antigen-expressing tumor and inducing an immune response against dominant in a non-human animal.

4.

发明申请
COMPOSITIONS AND METHODS FOR PREVENTION OF ESCAPE MUTATION IN THE TREATMENT OF HER2/NEU OVER-EXPRESSING TUMORS 审中-公开
标题翻译：用于预防HER2 / NEU过度表达肿瘤的ESCAPE突变的组合物和方法

公开(公告)号：US20150366955A9

公开(公告)日：2015-12-24

申请号：US14189008

申请日：2014-02-25

申请人： Advaxis, Inc. , The Trustees of the University of Pennsylvania

发明人： VAFA SHAHABI , Anu Wallecha , Paulo C. Maciag , Yvonne Paterson , Nicola Mason , Matthew M. Seavey

IPC分类号： A61K39/00

CPC分类号： A61K39/0011 , A61K2039/522 , A61K2039/523 , A61K2039/545 , A61K2039/55 , A61K2039/552 , A61K2039/572 , C07K14/195 , C07K14/82 , C07K2319/40 , C12N1/20 , C12N1/36 , C12N9/12 , C12N9/90 , C12N15/74 , C12Y207/10 , C12Y501/01001

摘要： This invention provides compositions and methods for treating and vaccinating against a Her2/neu antigen-expressing tumor and inducing an immune response against dominant in a non-human animal.

摘要翻译： 本发明提供用于治疗和接种针对Her2 / neu抗原表达的肿瘤并在非人动物中诱导针对显性的免疫应答的组合物和方法。