公开(公告)号：US20240255538A1

公开(公告)日：2024-08-01

申请号：US18103449

申请日：2023-01-30

申请人： Agilent Technologies, Inc.

发明人： Jonathan Irribarren ,  Lawrence D. Andrews

IPC分类号： G01N35/10

CPC分类号： G01N35/1074 ,  G01N35/1011 ,  G01N35/1016

摘要： A liquid dispensing device provides an input flow of liquid from a single inlet into an internal manifold, and distributes or divides the input flow from the manifold into a group of individual liquid circuits that direct respective output flows to outlets, from which controlled volumes of liquid can be dispensed into respective containers such as the wells of a multi-well plate. The volume of liquid dispensed into one container may be different from that dispensed into another container. Each liquid circuit may include a valve that regulates the liquid flow in that liquid circuit, which may be based on feedback from flow rate sensors. Two or more liquid dispensing devices may be stacked horizontally to provide additional unique liquid circuits and different liquids if desired.

公开(公告)号：US20240058813A1

公开(公告)日：2024-02-22

申请号：US17891636

申请日：2022-08-19

申请人： Agilent Technologies, Inc.

发明人： Jonathan Irribarren ,  Joel Myerson ,  Bo Curry

IPC分类号： B01L3/00

CPC分类号： B01L3/502715 ,  B01L2200/0605 ,  B01L2200/0621 ,  B01L2400/0481 ,  B01L2400/0487 ,  B01L2400/0638 ,  B01L2400/0655

摘要： A fluid delivery device is configured to create a pressure differential across a compartment in which a liquid resides, causing the liquid to flow through the compartment. After a period of time, the fluid delivery device is configured to eliminate the pressure differential and thereby equilibrate the pressure across the compartment, with the use of a pressure equilibration channel that is separate from the compartment. The compartment may contain a packed bed of solid phase particles such as beads. In such case, the pressure differential causes the liquid to flow through the packed bed. The liquid may include chemical reagents or precursors that participate in chemical reactions on or at the solid phase particles. The reactions may relate to chemical synthesis, for example the synthesis of bio-chemicals such as nucleotides.