公开(公告)号：US09183972B2

公开(公告)日：2015-11-10

申请号：US13146433

申请日：2010-07-05

申请人： Aimin Li ,  Chendong Shuang ,  Chao Long ,  Fuqiang Liu ,  Jinnan Wang ,  Qing Zhou ,  Yuzhi Xue ,  Youdong Zhou ,  Mancheng Zhang ,  Weiben Yang ,  Zhaolian Zhu

发明人： Aimin Li ,  Chendong Shuang ,  Chao Long ,  Fuqiang Liu ,  Jinnan Wang ,  Qing Zhou ,  Yuzhi Xue ,  Youdong Zhou ,  Mancheng Zhang ,  Weiben Yang ,  Zhaolian Zhu

IPC分类号： H01F1/01 ,  C08L33/24 ,  C08F2/44 ,  C08K3/22

CPC分类号： H01F1/01 ,  C08F2/44 ,  C08K2003/2265 ,  C08L33/24 ,  C22C2202/02 ,  Y10S428/90

摘要： This invention relates to the field of resin, particularly to a magnetic, acrylic strongly basic anion exchange microsphere resin and its manufacturing method. Its basic structure is as follow: wherein its matrix contains magnetic grains and A is a group containing quaternary ammonium salts; the manufacturing method is: taking acrylic compounds as the monomer and mixing it with the crosslinking agent and porogenic agent to form an oil phase; evenly mixing the oil phase with magnetic grains and then conducting suspension polymerization; aminating and alkylating the polymerized magnetic grains so as to form the quaternary ammonium salts, namely the magnetic, acrylic strongly basic anion exchange microsphere resin. The exchange capacity of this resin is higher than that of any magnetic strongly basic anion exchange microsphere resin available either on both Chinese and overseas markets or in literature; it is able to take the place of the traditional strongly basic anion exchange resin in separating and removing soluble organics, particularly precursors of disinfection by-products, and various anions such as nitrates and phosphates.

摘要翻译： 本发明涉及树脂领域，特别涉及磁性丙烯酸强碱性阴离子交换微球树脂及其制造方法。 其基本结构如下：其中基质含有磁性颗粒，A为含有季铵盐的基团; 制造方法是：以丙烯酸类化合物为单体，并与交联剂和致孔剂混合形成油相; 将油相与磁性颗粒均匀混合，然后进行悬浮聚合; 对聚合的磁性颗粒进行胺化和烷基化以形成季铵盐，即磁性，丙烯酸强碱性阴离子交换微球体树脂。 该树脂的交换能力高于中国和海外市场或文献中可获得的任何磁性强碱性阴离子交换微球树脂; 可以代替传统的强碱性阴离子交换树脂来分离和除去可溶性有机物，特别是消毒副产物的前体，以及各种阴离子如硝酸盐和磷酸盐。

公开(公告)号：US20130341554A1

公开(公告)日：2013-12-26

申请号：US13146433

申请日：2010-07-06

申请人： Aimin Li ,  Chendong Shuang ,  Chao Long ,  Fuqiang Liu ,  Jinnan Wang ,  Qing Zhou ,  Yuzhi Xue ,  Youdong Zhou ,  Mancheng Zhang ,  Weiben Yang ,  Zhaolian Zhu

发明人： Aimin Li ,  Chendong Shuang ,  Chao Long ,  Fuqiang Liu ,  Jinnan Wang ,  Qing Zhou ,  Yuzhi Xue ,  Youdong Zhou ,  Mancheng Zhang ,  Weiben Yang ,  Zhaolian Zhu

IPC分类号： H01F1/01

CPC分类号： H01F1/01 ,  C08F2/44 ,  C08K2003/2265 ,  C08L33/24 ,  C22C2202/02 ,  Y10S428/90

摘要： This invention relates to the field of resin, particularly to a magnetic, acrylic strongly basic anion exchange microsphere resin and its manufacturing method. Its basic structure is as follow: wherein its matrix contains magnetic grains and A is a group containing quaternary ammonium salts; the manufacturing method is: taking acrylic compounds as the monomer and mixing it with the cros slinking agent and porogenic agent to form an oil phase; evenly mixing the oil phase with magnetic grains and then conducting suspension polymerization; aminating and alkylating the polymerized magnetic grains so as to form the quaternary ammonium salts, namely the magnetic, acrylic strongly basic anion exchange microsphere resin. The exchange capacity of this resin is higher than that of any magnetic strongly basic anion exchange microsphere resin available either on both Chinese and overseas markets or in literature; it is able to take the place of the traditional strongly basic anion exchange resin in separating and removing soluble organics, particularly precursors of disinfection by-products, and various anions such as nitrates and phosphates.

摘要翻译： 本发明涉及树脂领域，特别涉及磁性丙烯酸强碱性阴离子交换微球树脂及其制造方法。 其基本结构如下：其中基质含有磁性颗粒，A为含有季铵盐的基团; 制造方法是：以丙烯酸类化合物为单体，并与交联剂和致孔剂混合形成油相; 将油相与磁性颗粒均匀混合，然后进行悬浮聚合; 对聚合的磁性颗粒进行胺化和烷基化以形成季铵盐，即磁性，丙烯酸强碱性阴离子交换微球体树脂。 该树脂的交换能力高于中国和海外市场或文献中可获得的任何磁性强碱性阴离子交换微球树脂; 可以代替传统的强碱性阴离子交换树脂来分离和除去可溶性有机物，特别是消毒副产物的前体，以及各种阴离子如硝酸盐和磷酸盐。

公开(公告)号：US20160333101A1

公开(公告)日：2016-11-17

申请号：US14757970

申请日：2015-12-23

申请人： Qing Zhou ,  Xiao Feng ,  Weihong Nian ,  Lingyun Li

发明人： Qing Zhou ,  Xiao Feng ,  Weihong Nian ,  Lingyun Li

IPC分类号： C07K16/28

CPC分类号： C07K16/2875 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/51 ,  C07K2317/515 ,  C07K2317/52 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2319/30

摘要： An anti-human RANKL antibody, a humanized antibody for the anti-human RANKL antibody, a pharmaceutical composition and a use thereof are provided. The anti-human RANKL antibody is capable of bonding specifically with an amino acid sequence of SEQ ID NO.1, a heavy chain of the anti-human RANKL antibody includes a variable region in one of amino acid sequences of SEQ ID NO.2-9, and a light chain of the anti-human RANKL antibody includes a variable region in one of amino acid sequences of SEQ ID NO.10-17. The humanized antibody is capable of bonding specifically with human RANKL, a variable region in a heavy chain of the humanized antibody is selected from amino acid sequences of SEQ ID NO.6, NO.23, NO.25, NO.27 or NO.29, and a variable region in a light chain of the humanized antibody is selected from amino acid sequences of SEQ ID NO.14, NO.31, NO.33, NO.35, NO.37 or NO.39.

摘要翻译： 提供抗人RANKL抗体，抗人RANKL抗体的人源化抗体，药物组合物及其用途。 抗人RANKL抗体能够与SEQ ID NO.1的氨基酸序列特异性结合，抗人RANKL抗体的重链包含SEQ ID NO.2-1的氨基酸序列之一的可变区， 9，抗人RANKL抗体的轻链包含SEQ ID NO.10-17的氨基酸序列之一的可变区。 人源化抗体能够与人RANKL特异性结合，人源化抗体重链中的可变区选自SEQ ID NO.6，NO.23，NO.25，NO.27或NO的氨基酸序列。 29，并且人源化抗体的轻链中的可变区选自SEQ ID NO.14，NO.31，NO.33，NO.35，NO37或NO.39的氨基酸序列。

公开(公告)号：US09064343B2

公开(公告)日：2015-06-23

申请号：US12861890

申请日：2010-08-24

申请人： Ruiduo Yang ,  Linda Ip ,  Michael D. Street ,  Qing Zhou

发明人： Ruiduo Yang ,  Linda Ip ,  Michael D. Street ,  Qing Zhou

IPC分类号： G06T15/10 ,  G06T15/00 ,  G06T1/20 ,  G06T15/30

CPC分类号： G06T15/30

摘要： Aspects of this disclosure are directed to techniques to store values indicative of one or more scissor regions in a scissor buffer. In aspects of this disclosure, a processor may receive two dimensional (2-D) coordinates of a scissor region. The processor may transform the 2-D coordinates into coordinates that include more than two dimensions. The processor may store a value indicative of the scissor region in one or more storage units of the scissor buffer based on the coordinates that include more than two dimensions.

摘要翻译： 本公开的方面涉及将指示剪刀缓冲器中的一个或多个剪刀区域的值存储的技术。 在本公开的方面，处理器可以接收剪刀区域的二维（2-D）坐标。 处理器可以将二维坐标变换为包括二维以上的坐标。 处理器可以基于包括多于两维的坐标将指示剪刀区域的值存储在剪刀缓冲器的一个或多个存储单元中。

公开(公告)号：US20140302055A1

公开(公告)日：2014-10-09

申请号：US13651665

申请日：2012-10-15

申请人： Haihong Zhong ,  Qing Zhou

发明人： Haihong Zhong ,  Qing Zhou

IPC分类号： C07K16/22 ,  A61K51/10 ,  G01N33/574 ,  A61K47/48

CPC分类号： C07K16/22 ,  A61K39/39533 ,  A61K47/6845 ,  A61K51/1021 ,  A61K2039/505 ,  A61P9/10 ,  A61P19/02 ,  A61P35/00 ,  C07K14/515 ,  C07K16/18 ,  C07K16/30 ,  C07K2317/21 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/92 ,  G01N33/57488

摘要： Antibodies directed to the antigen ANGPTL4 and uses of such antibodies. In accordance with the teachings herein, there are provided fully human monoclonal antibodies directed to the antigen ANGPTL4. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.

摘要翻译： 针对抗原ANGPTL4的抗体和这种抗体的用途。 根据本文的教导，提供针对抗原ANGPTL4的完全人单克隆抗体。 编码的核苷酸序列和包含重链和轻链免疫球蛋白分子的氨基酸序列，特别是对应于跨越框架区和/或互补决定区（CDR）的连续重链和轻链序列的序列，特别是从FR1至FR4或CDR1至CDR3 ，提供。 也提供了表达这种免疫球蛋白分子和单克隆抗体的杂交瘤或其它细胞系。

公开(公告)号：US08687595B2

公开(公告)日：2014-04-01

申请号：US13166418

申请日：2011-06-22

申请人： Yijun Yu ,  Zhongping Chen ,  Qing Zhou

发明人： Yijun Yu ,  Zhongping Chen ,  Qing Zhou

IPC分类号： H04W4/00

CPC分类号： H04W36/0011 ,  H04W36/0005 ,  H04W60/04

摘要： A method, an apparatus, and a system for implementing User Equipment (UE) handover are disclosed. A Mobility Management Entity (MME) obtains address information of a serving Interworking Function (IWF) by interacting with a function entity in a network and notifies the IWF to process handover according to the obtained IWF address information, so that the MME is capable of obtaining the address information of the serving IWF. Therefore, the normal proceeding of a UE handover procedure in a Circuit Switched over Packet Switched (CSoEPS) scenario is ensured.

摘要翻译： 公开了一种用于实现用户设备（UE）切换的方法，装置和系统。 移动管理实体（MME）通过与网络中的功能实体进行交互获取服务互通功能（IWF）的地址信息，并根据所获得的IWF地址信息通知IWF处理切换，从而MME能够获得 服务IWF的地址信息。 因此，确保了在电路交换分组交换（CSoEPS）场景中的UE切换过程的正常进行。

公开(公告)号：US08472948B2

公开(公告)日：2013-06-25

申请号：US13237314

申请日：2011-09-20

申请人： Cornel Pampu ,  Qing Zhou ,  Yu Yin ,  Wenfu Wu ,  Ha-yong Chen

发明人： Cornel Pampu ,  Qing Zhou ,  Yu Yin ,  Wenfu Wu ,  Ha-yong Chen

IPC分类号： H04W4/00 ,  H04M11/04

CPC分类号： H04W8/08 ,  H04W36/0055 ,  H04W36/385 ,  H04W48/18

摘要： The present invention provides a method for improving Network Discovery and Selection suitable for a UE which is moving into a new TA, which comprises: receiving, by a MMF, a TAU request including the new TA from the UE; allocating, by the MMF, a new TA List according to the new TA in the TAU request; sending, by the MMF, the new TA List to the UE; sending, by the MMF, a TA information to a Mobility Policy Function, MPF, for updating mobility policy of the UE if the new TA is a special TA covered by different networks.

公开(公告)号：US20120270556A1

公开(公告)日：2012-10-25

申请号：US13538800

申请日：2012-06-29

申请人： Yu Yin ,  Weilhua Hu ,  Qing Zhou

发明人： Yu Yin ,  Weilhua Hu ,  Qing Zhou

IPC分类号： H04W72/04

CPC分类号： H04W68/02 ,  H04W64/006 ,  H04W68/04

摘要： A method for allocating paging areas includes: determining a basic paging area currently visited by a User Equipment (UE); and allocating a paging area to this UE according to a history record of motion trace of UEs located in the basic paging area currently visited by this UE. An apparatus for allocating paging areas is disclosed.

摘要翻译： 一种分配寻呼区域的方法包括：确定用户设备（UE）当前访问的基本寻呼区域; 以及根据当前由该UE当前访问的基本寻呼区域中的UE的运动轨迹的历史记录向该UE分配寻呼区域。 公开了一种用于分配寻呼区域的设备。

公开(公告)号：US08271001B2

公开(公告)日：2012-09-18

申请号：US13073529

申请日：2011-03-28

申请人： Yu Yin ,  Weihua Hu ,  Qing Zhou

发明人： Yu Yin ,  Weihua Hu ,  Qing Zhou

IPC分类号： G06F15/16

CPC分类号： H04W68/02 ,  H04W64/006 ,  H04W68/04

摘要： A method for allocating paging areas includes: determining a basic paging area currently visited by a User Equipment (UE); and allocating a paging area to this UE according to a history record of motion trace of UEs located in the basic paging area currently visited by this UE. An apparatus for allocating paging areas is disclosed.

摘要翻译： 一种分配寻呼区域的方法包括：确定用户设备（UE）当前访问的基本寻呼区域; 以及根据当前由该UE当前访问的基本寻呼区域中的UE的运动轨迹的历史记录向该UE分配寻呼区域。 公开了一种用于分配寻呼区域的设备。

公开(公告)号：US20120084246A1

公开(公告)日：2012-04-05

申请号：US13324546

申请日：2011-12-13

申请人： Qing Zhou ,  Yin HU

发明人： Qing Zhou ,  Yin HU

IPC分类号： G06F17/00 ,  G06N5/02

CPC分类号： H04W4/24 ,  H04L12/14 ,  H04L12/1403

摘要： A decision-making method, a decision-making system, and a PDF are disclosed herein. The decision-making method comprises: receiving application session data that carries access network data and access user data; and making policy and charging decisions according to the application session data. Through the decision-making method, decision-making system, and PDF, the application session data comprises access network data and access user data of the UE so that the PCRF can uniquely determine a user according to the access network data or the access user data and the IP address allocated by the network to the UE, and make policy and charging decisions.

摘要翻译： 本文公开了决策方法，决策系统和PDF。 决策方法包括：接收携带接入网数据和接入用户数据的应用会话数据; 并根据应用会话数据制定策略和计费决定。 通过决策方法，决策系统和PDF，应用会话数据包括接入网络数据和接入UE的用户数据，使得PCRF可以根据接入网络数据或接入用户数据唯一地确定用户 以及由网络分配给UE的IP地址，并做出策略和计费决定。