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公开(公告)号：US20130260425A1
公开(公告)日：2013-10-03
申请号：US13912313
申请日：2013-06-07
Applicant: Ajinomoto Co., Inc.
Inventor： Hidetaka Doi , Yasushi Hoshino , Yuri Masumitsu , Yoshihiro Usuda
CPC classification number: C12P13/08 , C07K14/245 , C12N1/20 , C12N1/38 , C12N15/746 , C12P13/04
Abstract: A method for producing an L-amino acid includes culturing a bacterium which belongs to the family Enterobacteriaceae and has an L-amino acid-producing ability in a medium containing a carbon source selected from a fatty acid and an alcohol, and collecting the L-amino acid from the medium. A bacterium which has been subjected to a modification including at least one of enhancement of oxyS gene expression, enhancement of fixABC gene expression, and combination thereof, is used as the bacterium, or a substance that reduces intracellular hydrogen peroxide concentration of the bacterium is added to the medium.
Abstract translation: L-氨基酸的制造方法包括在含有选自脂肪酸和醇的碳源的培养基中培养属于肠杆菌科的细菌并具有L-氨基酸生产能力的细菌， 来自培养基的氨基酸。 使用已经进行了包括oxyS基因表达增强，固定化ABC基因表达的增强及其组合中的至少一种的修饰的细菌作为细菌，或者添加减少细菌的细胞内过氧化氢浓度的物质 到中等
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公开(公告)号：US08951760B2
公开(公告)日：2015-02-10
申请号：US13912313
申请日：2013-06-07
Applicant: Ajinomoto Co., Inc.
Inventor： Hidetaka Doi , Yasushi Hoshino , Yuri Masumitsu , Yoshihiro Usuda
CPC classification number: C12P13/08 , C07K14/245 , C12N1/20 , C12N1/38 , C12N15/746 , C12P13/04
Abstract: A method for producing an L-amino acid includes culturing a bacterium which belongs to the family Enterobacteriaceae and has an L-amino acid-producing ability in a medium containing a carbon source selected from a fatty acid and an alcohol, and collecting the L-amino acid from the medium. A bacterium which has been subjected to a modification including at least one of enhancement of oxyS gene expression, enhancement of fixABC gene expression, and combination thereof, is used as the bacterium, or a substance that reduces intracellular hydrogen peroxide concentration of the bacterium is added to the medium.
Abstract translation: L-氨基酸的制造方法包括在含有选自脂肪酸和醇的碳源的培养基中培养属于肠杆菌科的细菌并具有L-氨基酸生产能力的细菌， 来自培养基的氨基酸。 使用已经进行了包括oxyS基因表达增强，固定化ABC基因表达的增强及其组合中的至少一种的修饰的细菌作为细菌，或者添加减少细菌的细胞内过氧化氢浓度的物质 到中等
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