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公开(公告)号:US06844362B2
公开(公告)日:2005-01-18
申请号:US10684233
申请日:2003-10-09
申请人: Alan Daniel Brown , Justin Stephen Bryans , Mark Edward Bunnage , Paul Alan Glossop , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Simon Mantell
发明人: Alan Daniel Brown , Justin Stephen Bryans , Mark Edward Bunnage , Paul Alan Glossop , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Simon Mantell
IPC分类号: C07D209/42 , A61K31/404 , C07D209/04
CPC分类号: C07D209/42
摘要: The invention relates to indole derivatives and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The indole derivatives according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译: 本发明涉及吲哚衍生物和制备用于制备含有这些衍生物的组合物和用途的中间体的方法。 根据本发明的吲哚衍生物可用于许多疾病,病症和病症,特别是炎症,过敏和呼吸道疾病,病症和病症。
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公开(公告)号:US07138527B2
公开(公告)日:2006-11-21
申请号:US10959934
申请日:2004-10-05
申请人: Alan Daniel Brown , Justin Stephen Bryans , Mark Edward Bunnage , Paul Alan Glossop , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Simon Mantell
发明人: Alan Daniel Brown , Justin Stephen Bryans , Mark Edward Bunnage , Paul Alan Glossop , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Simon Mantell
IPC分类号: C07D209/04
CPC分类号: C07D209/42
摘要: The invention relates to indole derivatives and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The indole derivatives according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译: 本发明涉及吲哚衍生物和制备用于制备含有这些衍生物的组合物和用途的中间体的方法。 根据本发明的吲哚衍生物可用于许多疾病,病症和病症,特别是炎症,过敏和呼吸道疾病,病症和病症。
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公开(公告)号:US07183294B2
公开(公告)日:2007-02-27
申请号:US10800253
申请日:2004-03-12
申请人: Alan Daniel Brown , Justin Stephen Bryans , Mark Edward Bunnage , Paul Alan Glossop , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Simon John Mantell
发明人: Alan Daniel Brown , Justin Stephen Bryans , Mark Edward Bunnage , Paul Alan Glossop , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Simon John Mantell
IPC分类号: A61K31/4439 , A61K31/427 , A61K31/4045 , C07D401/12 , C07D209/14
CPC分类号: C07D209/42 , C07D401/12 , C07D417/12
摘要: The invention relates to indole derivatives and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The indole derivatives according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译: 本发明涉及吲哚衍生物和制备用于制备含有这些衍生物的组合物和用途的中间体的方法。 根据本发明的吲哚衍生物可用于许多疾病,病症和病症,特别是炎症,过敏和呼吸道疾病,病症和病症。
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公开(公告)号:US07547731B2
公开(公告)日:2009-06-16
申请号:US11773012
申请日:2007-07-03
申请人: Alan Daniel Brown , Mark Edward Bunnage , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Paul Alan Glossop , Kim James , David Anthony Price
发明人: Alan Daniel Brown , Mark Edward Bunnage , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Paul Alan Glossop , Kim James , David Anthony Price
IPC分类号: A61K31/167 , C07C233/24
CPC分类号: C07C237/20 , C07C237/30 , C07C237/32 , C07C255/60 , C07C311/37 , C07C311/46 , C07C317/32 , C07C323/32 , C07C323/41 , C07C323/42 , C07C2601/14 , C07C2602/08 , C07C2603/74 , C07D209/48 , C07D211/32 , C07D213/38 , C07D213/40 , C07D217/06 , C07D217/16 , C07D221/22 , C07D221/24 , C07D295/192 , C07D335/02
摘要: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译: 本发明涉及式(1)化合物以及制备用于制备含这些衍生物的组合物和用途的中间体的方法。 根据本发明的化合物可用于许多疾病,病症和病症,特别是炎症,过敏和呼吸道疾病,病症和病症。
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公开(公告)号:US07241810B2
公开(公告)日:2007-07-10
申请号:US11086035
申请日:2005-03-21
申请人: Alan Daniel Brown , Mark Edward Bunnage , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Paul Alan Glossop , Kim James , David Anthony Price
发明人: Alan Daniel Brown , Mark Edward Bunnage , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Paul Alan Glossop , Kim James , David Anthony Price
IPC分类号: A61K31/167 , C07C233/24
CPC分类号: C07C237/20 , C07C237/30 , C07C237/32 , C07C255/60 , C07C311/37 , C07C311/46 , C07C317/32 , C07C323/32 , C07C323/41 , C07C323/42 , C07C2601/14 , C07C2602/08 , C07C2603/74 , C07D209/48 , C07D211/32 , C07D213/38 , C07D213/40 , C07D217/06 , C07D217/16 , C07D221/22 , C07D221/24 , C07D295/192 , C07D335/02
摘要: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译: 本发明涉及式(1)化合物以及制备用于制备含这些衍生物的组合物和用途的中间体的方法。 根据本发明的化合物可用于许多疾病,病症和病症,特别是炎症,过敏和呼吸道疾病,病症和病症。
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公开(公告)号:US07538141B2
公开(公告)日:2009-05-26
申请号:US11086132
申请日:2005-03-21
申请人: Alan Daniel Brown , Mark Edward Bunnage , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Paul Alan Glossop , Kim James , David Anthony Price
发明人: Alan Daniel Brown , Mark Edward Bunnage , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Paul Alan Glossop , Kim James , David Anthony Price
IPC分类号: C07C233/00 , C07C235/00 , C07C237/00 , C07C239/00 , A01N37/18 , A61K31/16
CPC分类号: C07C237/20 , C07C237/30 , C07C255/60 , C07C311/46 , C07C323/41 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2603/74 , C07D211/58 , C07D213/40 , C07D213/75 , C07D217/06 , C07D231/40 , C07D413/04
摘要: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译: 本发明涉及式(1)化合物以及制备用于制备含这些衍生物的组合物和用途的中间体的方法。 根据本发明的化合物可用于许多疾病,病症和病症,特别是炎症,过敏和呼吸道疾病,病症和病症。
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公开(公告)号:US20080207689A1
公开(公告)日:2008-08-28
申请号:US11773012
申请日:2007-07-03
申请人: Alan Daniel Brown , Mark Edward Bunnage , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Paul Alan Glossop , Kim James , David Anthony Price
发明人: Alan Daniel Brown , Mark Edward Bunnage , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite , Paul Alan Glossop , Kim James , David Anthony Price
IPC分类号: A61K31/4035 , A61K31/165 , A61K31/445 , A61K31/44 , C07D211/30 , C07D209/44 , C07C237/00 , A61P11/06 , A61P37/08
CPC分类号: C07C237/20 , C07C237/30 , C07C237/32 , C07C255/60 , C07C311/37 , C07C311/46 , C07C317/32 , C07C323/32 , C07C323/41 , C07C323/42 , C07C2601/14 , C07C2602/08 , C07C2603/74 , C07D209/48 , C07D211/32 , C07D213/38 , C07D213/40 , C07D217/06 , C07D217/16 , C07D221/22 , C07D221/24 , C07D295/192 , C07D335/02
摘要: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译: 本发明涉及式(1)化合物以及制备用于制备含这些衍生物的组合物和用途的中间体的方法。 根据本发明的化合物可用于许多疾病,病症和病症,特别是炎症,过敏和呼吸道疾病,病症和病症。
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公开(公告)号:US07629358B2
公开(公告)日:2009-12-08
申请号:US11083265
申请日:2005-03-16
申请人: Alan Daniel Brown , Charlotte Alice Louise Lane , Paul Alan Glossop , David Anthony Price , Russell Andrew Lewthwaite , Mark Edward Bunnage , Kim James , Graham Lunn
发明人: Alan Daniel Brown , Charlotte Alice Louise Lane , Paul Alan Glossop , David Anthony Price , Russell Andrew Lewthwaite , Mark Edward Bunnage , Kim James , Graham Lunn
IPC分类号: A61K31/47 , A61K31/165 , C07D217/00 , C07C237/00
CPC分类号: C07D217/06 , C07C237/20 , C07C237/30 , C07C237/32 , C07C237/34 , C07C237/36 , C07C311/46 , C07C323/42 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/08 , C07C2603/74 , C07D213/40 , C07D235/14 , C07D239/26 , C07D295/088 , C07D295/13 , C07D295/26
摘要: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译: 本发明涉及式(1)化合物以及制备用于制备含这些衍生物的组合物和用途的中间体的方法。 根据本发明的化合物可用于许多疾病,病症和病症,特别是炎症,过敏和呼吸道疾病,病症和病症。
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公开(公告)号:US07268147B2
公开(公告)日:2007-09-11
申请号:US10840770
申请日:2004-05-06
申请人: Mark Edward Bunnage , Paul Alan Glossop , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite
发明人: Mark Edward Bunnage , Paul Alan Glossop , Charlotte Alice Louise Lane , Russell Andrew Lewthwaite
IPC分类号: A61K31/47 , A61K31/4439 , C07D217/02
CPC分类号: C07D213/75 , C07C237/20 , C07C237/22 , C07C311/46 , C07C2602/08 , C07D209/44 , C07D217/06
摘要: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译: 本发明涉及式(1)化合物以及制备用于制备含这些衍生物的组合物和用途的中间体的方法。 根据本发明的化合物可用于许多疾病,病症和病症,特别是炎症,过敏和呼吸道疾病,病症和病症。
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公开(公告)号:US07482487B2
公开(公告)日:2009-01-27
申请号:US10598843
申请日:2005-03-10
申请人: Alan Daniel Brown , Justin Stephen Bryans , Paul Alan Glossop , Charlotte Alice Louise Lane , Simmon John Mantell
发明人: Alan Daniel Brown , Justin Stephen Bryans , Paul Alan Glossop , Charlotte Alice Louise Lane , Simmon John Mantell
IPC分类号: C07C233/05 , A61K31/65
CPC分类号: C07C237/42 , C07C237/20 , C07C275/24 , C07C311/46
摘要: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译: 本发明涉及式(1)化合物以及制备用于制备含这些衍生物的组合物和用途的中间体的方法。 根据本发明的化合物可用于许多疾病,病症和病症,特别是炎症,过敏和呼吸道疾病,病症和病症。
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