Method for tumor detection and treatment
    3.
    发明授权
    Method for tumor detection and treatment 失效
    肿瘤检测和治疗方法

    公开(公告)号:US5277894A

    公开(公告)日:1994-01-11

    申请号:US22449

    申请日:1993-02-25

    摘要: The invention relates to a method of detecting an Fc receptor-expressing tumor site in an individual by administering to the individual a diagnostically effective amount of detectably-labeled non-specific immunoglobulin or Fc or Fc' fragment thereof, wherein the immunoprotein substantially accumulates at the site when the site bears such a tumor. By using a therapeutically-labeled specific or non-specific immunoglobulin or Fc or Fc' fragment thereof, the tumor may be treated therapeutically.

    摘要翻译: 本发明涉及通过向个体施用诊断有效量的可检测标记的非特异性免疫球蛋白或其Fc或Fc'片段来检测个体中Fc受体表达的肿瘤位点的方法,其中所述免疫蛋白基本上在 当站点承载如此肿瘤时。 通过使用治疗标记的特异性或非特异性免疫球蛋白或其Fc或Fc'片段,可以治疗性地治疗肿瘤。

    Method for tumor detection
    4.
    发明授权
    Method for tumor detection 失效
    肿瘤检测方法

    公开(公告)号:US5200178A

    公开(公告)日:1993-04-06

    申请号:US731384

    申请日:1991-07-16

    IPC分类号: A61K47/48 A61K51/10

    摘要: The invention relates to a method of detecting an Fc receptor-expressing tumor site in an individual by administering to the individual a diagnostically effective amount of detectably-labeled non-specific immunoglobulin or Fc or Fc' fragment thereof, wherein the immunoprotein substantially accumulates at the site when the site bears such a tumor. By using a therapeutically-labeled specific or non-specific immunoglobulin or Fc or Fc' fragment thereof, the tumor may be treated therapeutically.

    摘要翻译: 本发明涉及通过向个体施用诊断有效量的可检测标记的非特异性免疫球蛋白或其Fc或Fc'片段来检测个体中Fc受体表达的肿瘤位点的方法,其中所述免疫蛋白基本上在 当站点承载如此肿瘤时。 通过使用治疗标记的特异性或非特异性免疫球蛋白或其Fc或Fc'片段,可以治疗性地治疗肿瘤。

    Methods and apparatus for characterizing lesions in blood vessels and other body lumens
    7.
    发明授权
    Methods and apparatus for characterizing lesions in blood vessels and other body lumens 失效
    表征血管和其他体腔损伤的方法和装置

    公开(公告)号:US06782289B1

    公开(公告)日:2004-08-24

    申请号:US09670412

    申请日:2000-09-26

    IPC分类号: A61B600

    摘要: Methods, devices, and kits, for assessing luminal lesions are provided. The subject devices comprise an intraluminal detector capable of sensing radioactive or other labels. In the subject methods, a detectable marker is introduced to a body lumen, either into the lumen itself or systemically in patient circulation, and localizes at a lesion. The detector is introduced into the body lumen and the distribution of a localized marker detected in situ. The information is useful for a number of purposes including the identification of unstable plaque in patients suffering from atherosclerotic disease.

    摘要翻译: 提供了用于评估腔内损伤的方法,装置和试剂盒。 主题装置包括能够感测放射性或其他标签的管腔内检测器。 在本发明的方法中,将可检测标记物引入体腔,或者在患者循环中进入腔内或全身,并将其定位在病变处。 将检测器引入体腔,并在原位检测到局部标记的分布。 该信息对于许多目的是有用的,包括在患有动脉粥样硬化疾病的患者中识别不稳定斑块。

    Ambulatory ventricular function monitor
    8.
    发明授权
    Ambulatory ventricular function monitor 失效
    动态心室功能监测仪

    公开(公告)号:US4633881A

    公开(公告)日:1987-01-06

    申请号:US394465

    申请日:1982-07-01

    摘要: An ambulatory ventricular function anaylzer system is provided. The ambulatory ventricular function analyzer system is carried by a garment worn by a cardiac patient and includes ECG electrodes, a main left ventricular probe detector, and a background lung probe detector for providing diagnostically useful information while the patient goes about the normal activities of daily life. An information processing sub-system including a microprocessor responds to the electrode signal and to the probe signals and provides composite data representative of the ECG activity, the background lung time-activity, the left ventricular time-activity, and an R-wave histogram averaged over multiple cardiac cycles. The averaged data is sequentially sotred over a long time interval on magnetic tape in plural categories representing premature ventricular contraction, postpremature ventricular contraction, and normal ventricular contraction for subsequent display on a computer-based graphics display for study by a cardiac specialist. The main left ventricular function probe detector includes an array of cadmium telluride crystals mounted in a Pb housing having a parallel hole Pb collimator. The detector is substantially insensitive to position changes that arise during ambulatory monitoring.

    摘要翻译: 提供动态心室功能分析系统。 动态心室功能分析仪系统由心脏病患者佩戴的衣服携带,包括心电图电极,主要左心室探针检测器和背景肺探针检测器,用于在患者进行日常生活的正常活动时提供诊断上有用的信息 。 包括微处理器的信息处理子系统响应于电极信号和探针信号,并提供表示ECG活动,背景肺时间活动度,左心室时间活动度和R波直方图平均值的复合数据 超过多个心动周期。 平均数据在多个类别的磁带上以多个类别顺序地排列,代表心室早期心室收缩,心室后收缩和正常心室收缩,以便随后在基于计算机的图形显示器上显示以供心脏专家研究。 主要的左心室功能探针检测器包括安装在具有平行孔Pb准直器的Pb壳体中的碲化镉晶体阵列。 检测器对在行走监测期间出现的位置变化基本上不敏感。