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    ORAL CARE METHOD AND KIT
    2.
    发明申请
    ORAL CARE METHOD AND KIT 有权
    口腔护理方法和包装

    公开(公告)号：US20100285148A1

    公开(公告)日：2010-11-11

    申请号：US12775197

    申请日：2010-05-06

    申请人： Katie F. Wlaschin ,  Alan R. Dombrowski ,  Matthew T. Scholz ,  Ranjani V. Parthasarathy

    发明人： Katie F. Wlaschin ,  Alan R. Dombrowski ,  Matthew T. Scholz ,  Ranjani V. Parthasarathy

    IPC分类号： A61K33/40 ,  A61K31/155 ,  A61P31/00

    CPC分类号： A61K31/155 ,  A61M16/04

    摘要： A method of moisturizing while decolonizing mammalian tissue, the method comprising applying a multi-valent cationic antiseptic composition to the tissue, and applying a moisturizer composition to at least a portion of the same tissue; wherein the mammalian tissue is oral tissue of a subject; wherein the multi-valent cationic antiseptic is other than a metal ion; and wherein the applied compositions essentially exclude any component which causes a precipitate when combined with a multi-valent cationic antiseptic contained in the multi-valent cationic antiseptic composition when tested according to Test Method F, and/or wherein the moisturizer composition is such that a log reduction in the number of viable bacterial cells of at least 2 is provided when 106 cfu of Pseudomonas auerginosa are combined with a mixture 1.1 g of the moisturizer composition and 1.5 g of the multi-valent cationic antiseptic composition containing 0.12 weight percent of the multi-valent cationic antiseptic according to Test Method B; an oral care kit comprising a composition comprising the multi-valent cationic antiseptic and the moisturizer composition; and a method of moisturizing oral tissue of a patient requiring intubation using the moisturizer composition and an endotracheal tube coated or impregnated with a cationic antiseptic are provided.

    摘要翻译： 一种在哺乳动物组织非殖化时保湿的方法，该方法包括将多价阳离子防腐组合物施用于组织，以及将保湿组合物施用于相同组织的至少一部分; 其中哺乳动物组织是受试者的口腔组织; 其中所述多价阳离子防腐剂不是金属离子; 并且其中当根据测试方法F测试时，所施加的组合物基本上排除任何与多价阳离子防腐组合物中所含的多价阳离子防腐剂组合时引起沉淀的组分，和/或其中所述保湿组合物使得 当将106cfu的绿脓假单胞菌与1.1g的保湿组合物和1.5g多价阳离子防腐组合物混合在一起时，提供至少为2的活细菌细胞的数量减少，该组合物含有0.12重量％的多 根据测试方法B的阳离子抗菌剂; 口腔护理套件，其包含包含所述多价阳离子防腐剂和所述保湿组合物的组合物; 提供了使用保湿组合物和使用阳离子防腐剂涂布或浸渍的气管内导管的需要插管的患者的口腔组织的保湿方法。

    Oral care method and kit
    3.
    发明授权
    Oral care method and kit 有权
    口腔护理方法和试剂盒

    公开(公告)号：US08460689B2

    公开(公告)日：2013-06-11

    申请号：US12775197

    申请日：2010-05-06

    申请人： Katie F. Wlaschin ,  Alan R. Dombrowski ,  Matthew T. Scholz ,  Ranjani V. Parthasarathy

    发明人： Katie F. Wlaschin ,  Alan R. Dombrowski ,  Matthew T. Scholz ,  Ranjani V. Parthasarathy

    IPC分类号： A61K8/43 ,  A61K6/00 ,  A61K31/155

    CPC分类号： A61K31/155 ,  A61M16/04

    摘要： A method of moisturizing while decolonizing mammalian tissue, the method comprising applying a multi-valent cationic antiseptic composition to the tissue, and applying a moisturizer composition to at least a portion of the same tissue; wherein the mammalian tissue is oral tissue of a subject; wherein the multi-valent cationic antiseptic is other than a metal ion; and wherein the applied compositions essentially exclude any component which causes a precipitate when combined with a multi-valent cationic antiseptic contained in the multi-valent cationic antiseptic composition when tested according to Test Method F, and/or wherein the moisturizer composition is such that a log reduction in the number of viable bacterial cells of at least 2 is provided when 106 cfu of Pseudomonas aeruginosa are combined with a mixture 1.1 g of the moisturizer composition and 1.5 g of the multi-valent cationic antiseptic composition containing 0.12 weight percent of the multi-valent cationic antiseptic according to Test Method B; an oral care kit comprising a composition comprising the multi-valent cationic antiseptic and the moisturizer composition; and a method of moisturizing oral tissue of a patient requiring intubation using the moisturizer composition and an endotracheal tube coated or impregnated with a cationic antiseptic are provided.

    摘要翻译： 一种在哺乳动物组织非殖化时保湿的方法，该方法包括将多价阳离子防腐组合物施用于组织，以及将保湿组合物施用于相同组织的至少一部分; 其中哺乳动物组织是受试者的口腔组织; 其中所述多价阳离子防腐剂不是金属离子; 并且其中当根据测试方法F测试时，所施加的组合物基本上排除任何与多价阳离子防腐组合物中所含的多价阳离子防腐剂组合时引起沉淀的组分，和/或其中所述保湿组合物使得 当将106 cfu的绿脓假单胞菌与1.1g的保湿组合物和1.5g多价阳离子防腐剂组合物混合在一起时，提供至少2个活细菌细胞数目的对数减少，该组合物含有0.12重量％的多 根据测试方法B的阳离子抗菌剂; 口腔护理套件，其包含包含所述多价阳离子防腐剂和所述保湿组合物的组合物; 提供了使用保湿组合物和使用阳离子防腐剂涂布或浸渍的气管内导管的需要插管的患者的口腔组织的保湿方法。