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公开(公告)号：US08016811B2
公开(公告)日：2011-09-13
申请号：US10691968
申请日：2003-10-24
IPC分类号： A61M31/00
CPC分类号： A61M37/00 , A61K9/0009 , A61K9/0046 , A61M37/0015 , A61M37/0092 , A61M2037/0007 , A61M2037/0023 , A61M2037/0061 , A61N1/0412 , A61N1/30 , A61N1/327
摘要： A method for delivering permeant substances transdermally into a membrane of an animal includes forming at least one delivery opening in the skin tissue, with the at least one delivery opening having a mean opening depth of between about 40 and about 90 microns.
摘要翻译： 透皮物质经皮递送到动物膜中的方法包括在皮肤组织中形成至少一个输送口，其中所述至少一个输送口的平均开口深度在约40至约90微米之间。
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公开(公告)号：US20120101426A1
公开(公告)日：2012-04-26
申请号：US13194328
申请日：2011-07-29
CPC分类号： A61M37/00 , A61K9/0009 , A61K9/0046 , A61M37/0015 , A61M37/0092 , A61M2037/0007 , A61M2037/0023 , A61M2037/0061 , A61N1/0412 , A61N1/30 , A61N1/327
摘要： A method for delivering permeant substances transdermally into a membrane of an animal includes forming at least one delivery opening in the skin tissue, with the at least one delivery opening having a mean opening depth of between about 40 and about 90 microns.
摘要翻译： 透皮物质经皮递送到动物膜中的方法包括在皮肤组织中形成至少一个输送口，其中所述至少一个输送口的平均开口深度在约40至约90微米之间。
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公开(公告)号：US20150265823A1
公开(公告)日：2015-09-24
申请号：US14693592
申请日：2015-04-22
IPC分类号： A61M37/00
CPC分类号： A61M37/00 , A61K9/0009 , A61K9/0046 , A61M37/0015 , A61M37/0092 , A61M2037/0007 , A61M2037/0023 , A61M2037/0061 , A61N1/0412 , A61N1/30 , A61N1/327
摘要： A method for delivering permeant substances transdermally into a membrane of an animal includes forming at least one delivery opening in the skin tissue, with the at least one delivery opening having a mean opening depth of between about 40 and about 90 microns.
摘要翻译： 透皮物质经皮递送到动物膜中的方法包括在皮肤组织中形成至少一个输送口，其中该至少一个输送口的平均开口深度在约40至约90微米之间。
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公开(公告)号：US09033950B2
公开(公告)日：2015-05-19
申请号：US13194328
申请日：2011-07-29
CPC分类号： A61M37/00 , A61K9/0009 , A61K9/0046 , A61M37/0015 , A61M37/0092 , A61M2037/0007 , A61M2037/0023 , A61M2037/0061 , A61N1/0412 , A61N1/30 , A61N1/327
摘要： A method for delivering permeant substances transdermally into a membrane of an animal includes forming at least one delivery opening in the skin tissue, with the at least one delivery opening having a mean opening depth of between about 40 and about 90 microns.
摘要翻译： 透皮物质经皮递送到动物膜中的方法包括在皮肤组织中形成至少一个输送口，其中所述至少一个输送口的平均开口深度在约40至约90微米之间。
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公开(公告)号：US20050090800A1
公开(公告)日：2005-04-28
申请号：US10691968
申请日：2003-10-24
IPC分类号： A61K9/00 , A61M20060101 , A61M31/00
CPC分类号： A61M37/00 , A61K9/0009 , A61K9/0046 , A61M37/0015 , A61M37/0092 , A61M2037/0007 , A61M2037/0023 , A61M2037/0061 , A61N1/0412 , A61N1/30 , A61N1/327
摘要： A method for delivering permeant substances transdermally into a membrane of an animal includes forming at least one delivery opening in the skin tissue, with the at least one delivery opening having a mean opening depth of between about 40 and about 90 microns.
摘要翻译： 透皮物质经皮递送到动物膜中的方法包括在皮肤组织中形成至少一个输送口，其中所述至少一个输送口的平均开口深度在约40至约90微米之间。
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公开(公告)号：US08641689B2
公开(公告)日：2014-02-04
申请号：US13272592
申请日：2011-10-13
申请人： Bernadette Messier , Zoran Novakovic , Jeremiah Peter O'Leary , Regina Spiehl , Wendy E. Bowerman , Stephen Wilson Braun , Jonathan Eppstein , David Farquhar , Mark James Fisher , Uros Kascak , Erin Koch Henkel , Loren J. Lantz , Stuart McRae
发明人： Bernadette Messier , Zoran Novakovic , Jeremiah Peter O'Leary , Regina Spiehl , Wendy E. Bowerman , Stephen Wilson Braun , Jonathan Eppstein , David Farquhar , Mark James Fisher , Uros Kascak , Erin Koch Henkel , Loren J. Lantz , Stuart McRae
CPC分类号： A61N1/327 , A61N1/0412 , A61N1/0428 , A61N1/0476 , A61N1/325
摘要： A transdermal permeant delivery system for delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substrate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substrate.
摘要翻译： 一种用于将至少一种渗透性组合物输送到受试者的组织膜中的透皮渗透物递送系统，包括一次性基底，其具有连接到所述基底的上表面的第一释放衬垫的底表面的至少一部分，以及具有 背衬层和可从第一释放衬垫的顶表面选择性地移除的储存器。 在连接位置，贴片的背衬层的第一部分可释放地安装到第一剥离衬垫的顶表面，与衬底的引孔区间隔开对准。
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公开(公告)号：US08116860B2
公开(公告)日：2012-02-14
申请号：US12017996
申请日：2008-01-22
申请人： Bernadette Messier , Zoran Novakovic , Jeremiah Peter O'Leary , Regina Spiehl , Wendy E. Bowerman , Stephen Wilson Braun , Jonathan Eppstein , David Farquhar , Mark James Fisher , Uros Kascak , Erin Koch Henkel , Loren J. Lantz , Stuart McRae
发明人： Bernadette Messier , Zoran Novakovic , Jeremiah Peter O'Leary , Regina Spiehl , Wendy E. Bowerman , Stephen Wilson Braun , Jonathan Eppstein , David Farquhar , Mark James Fisher , Uros Kascak , Erin Koch Henkel , Loren J. Lantz , Stuart McRae
CPC分类号： A61N1/327 , A61N1/0412 , A61N1/0428 , A61N1/0476 , A61N1/325
摘要： A transdermal permeant delivery system for delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substrate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substrate.
摘要翻译： 一种用于将至少一种渗透性组合物输送到受试者的组织膜中的透皮渗透物递送系统，包括一次性基底，其具有连接到所述基底的上表面的第一释放衬垫的底表面的至少一部分，以及具有 背衬层和可从第一释放衬垫的顶表面选择性地移除的储存器。 在连接位置，贴片的背衬层的第一部分可释放地安装到第一剥离衬垫的顶表面，与衬底的引孔区间隔开对准。
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公开(公告)号：US20120035555A1
公开(公告)日：2012-02-09
申请号：US13272592
申请日：2011-10-13
申请人： Bernadette Messier , Zoran Novakovic , Jeremiah Peter O'Leary , Regina Spiehl , Wendy E. Bowerman , Stephen Wilson Braun , Jonathan Eppstein , David Farquhar , Mark James Fisher , Uros Kascak , Erin Koch Henkel , Loren J. Lantz , Stuart McRae
发明人： Bernadette Messier , Zoran Novakovic , Jeremiah Peter O'Leary , Regina Spiehl , Wendy E. Bowerman , Stephen Wilson Braun , Jonathan Eppstein , David Farquhar , Mark James Fisher , Uros Kascak , Erin Koch Henkel , Loren J. Lantz , Stuart McRae
IPC分类号： A61M35/00
CPC分类号： A61N1/327 , A61N1/0412 , A61N1/0428 , A61N1/0476 , A61N1/325
摘要： A transdermal permeant delivery system for delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substrate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substrate.
摘要翻译： 一种用于将至少一种渗透性组合物输送到受试者的组织膜中的透皮渗透物递送系统，包括一次性基底，其具有连接到所述基底的上表面的第一释放衬垫的底表面的至少一部分，以及具有 背衬层和可从第一释放衬垫的顶表面选择性地移除的储存器。 在连接位置，贴片的背衬层的第一部分可释放地安装到第一剥离衬垫的顶表面，与衬底的引孔区间隔开对准。
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公开(公告)号：US20120245505A1
公开(公告)日：2012-09-27
申请号：US13511548
申请日：2010-12-14
申请人： Michael R. Robinson , Werhner C. Orilla , Zoran Novakovic , James A. Burke , Alazar N. Ghebremeskel , Lon T. Spada
发明人： Michael R. Robinson , Werhner C. Orilla , Zoran Novakovic , James A. Burke , Alazar N. Ghebremeskel , Lon T. Spada
CPC分类号： A61F9/0017 , A61F9/00781 , A61K9/0051 , A61K9/0092
摘要： Described herein are intracameral drug and/or therapeutic bioactive agent delivery devices comprising a substantially cylindrical structure for at least partial placement into the anterior chamber of an eye The intracameral delivery devices have a sustained release material associated with at least a portion of the device and at least one drug and/or therapeutic bioactive agent associated with said sustained release material.
摘要翻译： 本文描述的是包括用于至少部分地放置到眼睛前房中的基本圆柱形结构的房内药物和/或治疗性生物活性剂递送装置。室内输送装置具有与装置的至少一部分相关联的持续释放材料，并且在 与所述缓释材料相关的至少一种药物和/或治疗性生物活性剂。
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公开(公告)号：USD605775S1
公开(公告)日：2009-12-08
申请号：US29321862
申请日：2008-07-24
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