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公开(公告)号:US06632349B1
公开(公告)日:2003-10-14
申请号:US09616512
申请日:2000-07-14
申请人: Alastair Hodges , Ron Chatelier , Thomas Beck
发明人: Alastair Hodges , Ron Chatelier , Thomas Beck
IPC分类号: G01N27327
摘要: The present invention relates to a device and method for measuring hemoglobin in a fluid sample. The device comprises a disposable electrochemical cell, such as a thin layer electrochemical cell, containing a reagent capable of being reduced by hemoglobin. A suitable fluid sample that may be analyzed according the present invention is whole blood. If the hemoglobin to be analyzed is present in red blood cells, a lysing agent may be added to the sample to release the hemoglobin prior to analysis.
摘要翻译: 本发明涉及一种用于测量流体样品中血红蛋白的装置和方法。 该装置包括一次性电化学电池,例如薄层电化学电池,其含有能够被血红蛋白还原的试剂。 根据本发明可以分析的合适的流体样品是全血。 如果要分析的血红蛋白存在于红细胞中,则可以在分析前将裂解剂加入样品中以释放血红蛋白。 PTEXT>
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公开(公告)号:US20050173246A1
公开(公告)日:2005-08-11
申请号:US10624823
申请日:2003-07-22
申请人: Alastair Hodges , Thomas Beck , Oddvar Johansen
发明人: Alastair Hodges , Thomas Beck , Oddvar Johansen
IPC分类号: C12Q1/00 , G01N27/327 , G01N27/49 , G01N27/26
CPC分类号: G01N27/403 , C12Q1/004 , G01N27/3272 , G01N27/3273 , Y10T29/49117
摘要: This invention relates to a biosensor and more particularly to an electrochemical biosensor for determining the concentration of an analyte in a carrier. The invention is particularly useful for determining the concentration of glucose in blood and is described herein with reference to that use but it should be understood that the invention is applicable to other analytic determinations.
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公开(公告)号:US20060201804A1
公开(公告)日:2006-09-14
申请号:US11434442
申请日:2006-05-15
申请人: Garry Chambers , Alastair Hodges , Thomas Beck , Ian Maxwell
发明人: Garry Chambers , Alastair Hodges , Thomas Beck , Ian Maxwell
IPC分类号: G01N27/26
CPC分类号: G01N27/3272
摘要: The invention relates to a sensor adapted for electrical connection to a power source having an electrical contact means (3). The sensor has a first insulating substrate (1) carrying a first electrode (2) and a second insulating substrate (7) carrying a second electrode (6). The electrodes are disposed to face each other in spaced apart relationship, sandwiching a spacer (4) therebetween. A first cut-out portion extends through the first insulating substrate (1) and a spacer (4) to expose a first contact area (23) on the second insulating substrate (7). This permits the electrical contact means (31) to effect electrical connection with the first contact (23) which in turn is in electrically conductive connection with the second electrode (6). A similar contact arrangement may be disposed on the opposite side of the sensor.
摘要翻译: 本发明涉及适于与具有电接触装置(3)的电源电连接的传感器。 传感器具有承载第一电极(2)的第一绝缘基板(1)和承载第二电极(6)的第二绝缘基板(7)。 这些电极被设置为以间隔开的方式彼此面对,将间隔物(4)夹在其间。 第一切口部分延伸穿过第一绝缘基板(1)和间隔件(4)以暴露第二绝缘基板(7)上的第一接触区域(23)。 这允许电接触装置(31)实现与第一接触件(23)的电连接,第一触头(23)又与第二电极(6)导电连接。 类似的接触装置可以设置在传感器的相对侧上。
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公开(公告)号:US20060163061A1
公开(公告)日:2006-07-27
申请号:US11392201
申请日:2006-03-29
申请人: Alastair Hodges , Thomas Beck , Ian Maxwell
发明人: Alastair Hodges , Thomas Beck , Ian Maxwell
IPC分类号: G01N27/26
CPC分类号: G01N27/3272
摘要: The invention relates to an amperometric electrochemical cell having a first insulating substrate carrying a first electrode, a second insulting substrate carrying a second electrode, said electrodes being disposed to face each other and spaced apart by less than 500 μm, and defining a sample reservoir therebetween, and wherein at least one, and preferably both, insulating substrates and the electrode carried thereon include an electromagnetic radiation transmissive portion in registration with said reservoir. The walls of the electrochemical cell may be formed from a thin metallic portion on a transparent substrate. Such cells are useful in providing visual confirmation of the validity of the electrochemical measurement.
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公开(公告)号:US20050126931A1
公开(公告)日:2005-06-16
申请号:US11047859
申请日:2005-02-01
申请人: Ian Maxwell , Thomas Beck , Alastair Hodges
发明人: Ian Maxwell , Thomas Beck , Alastair Hodges
IPC分类号: G01N27/416 , G01N27/403 , G01N35/00 , G01N35/02 , G01N27/26
CPC分类号: G01N27/4168 , G01N35/00029
摘要: This invention relates to a method for analyzing the concentration of an analyte in a sample and to automatic analyzing apparatus. The invention will be described herein with particular reference to a method and apparatus for measuring the concentration of glucose or other analytes in blood but is not limited to that use.
摘要翻译: 本发明涉及一种用于分析样品中分析物的浓度和自动分析装置的方法。 本文将特别参考用于测量血液中葡萄糖或其他分析物的浓度的方法和装置来描述本发明,但不限于此。
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公开(公告)号:US20050077176A1
公开(公告)日:2005-04-14
申请号:US10624795
申请日:2003-07-22
申请人: Alastair Hodges , Thomas Beck , Oddvar Johansen
发明人: Alastair Hodges , Thomas Beck , Oddvar Johansen
IPC分类号: C12Q1/00 , G01N27/327 , G01N27/49 , G01N27/26
CPC分类号: G01N27/403 , C12Q1/004 , G01N27/3272 , G01N27/3273 , Y10T29/49117
摘要: This invention relates to a biosensor and more particularly to an electrochemical biosensor for determining the concentration of an analyte in a carrier. The invention is particularly useful for determining the concentration of glucose in blood and is described herein with reference to that use but it should be understood that the invention is applicable to other analytic determinations.
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公开(公告)号:US20060254932A1
公开(公告)日:2006-11-16
申请号:US11487728
申请日:2006-07-17
申请人: Alastair Hodges , Thomas Beck , Oddvar Johansen , Ian Maxwell
发明人: Alastair Hodges , Thomas Beck , Oddvar Johansen , Ian Maxwell
IPC分类号: G01N27/26 , G01N33/487
CPC分类号: C12Q1/004 , C12Q1/006 , G01N27/3272
摘要: A biosensor for use in determining a concentration of a component in an aqueous liquid sample is provided including: an electrochemical cell having a first electrically resistive substrate having a thin layer of electrically conductive material, a second electrically resistive substrate having a thin layer of electrically conductive material, the substrates being disposed with the electrically conductive materials facing each other and being separated by a sheet including an aperture, the wall of which aperture defines a cell wall and a sample introduction aperture whereby the aqueous liquid sample may be introduced into the cell; and a measuring circuit.
摘要翻译: 提供了一种用于确定含水液体样品中组分浓度的生物传感器,包括:电化学电池,具有具有导电材料薄层的第一电阻衬底,具有导电薄层的第二电阻衬底 材料,所述基板被布置成导电材料相互面对并由包括孔的片分隔开,所述片的壁的孔限定细胞壁和样品引入孔,由此可将水性液体样品引入细胞中; 和测量电路。
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公开(公告)号:US20050098431A1
公开(公告)日:2005-05-12
申请号:US10624746
申请日:2003-07-22
申请人: Alastair Hodges , Thomas Beck , Oddvar Johansen
发明人: Alastair Hodges , Thomas Beck , Oddvar Johansen
IPC分类号: C12Q1/00 , G01N27/327 , G01N27/49 , G01N27/26
CPC分类号: G01N27/403 , C12Q1/004 , G01N27/3272 , G01N27/3273 , Y10T29/49117
摘要: This invention relates to a biosensor and more particularly to an electrochemical biosensor for determining the concentration of an analyte in a carrier. The invention is particularly useful for determining the concentration of glucose in blood and is described herein with reference to that use but it should be understood that the invention is applicable to other analytic determinations.
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公开(公告)号:US20050034983A1
公开(公告)日:2005-02-17
申请号:US10950111
申请日:2004-09-24
申请人: Garry Chambers , Alastair Hodges , Thomas Beck , Ian Maxwell
发明人: Garry Chambers , Alastair Hodges , Thomas Beck , Ian Maxwell
IPC分类号: G01N27/28 , G01N20060101 , G01N27/327 , G01N27/403 , G01N33/487 , H01L21/8228 , C12M1/00
CPC分类号: G01N27/3272
摘要: The invention relates to a sensor adapted for electrical connection to a power source having an electrical contact means (3). The sensor has a first insulating substrate (1) carrying a first electrode (2) and a second insulating substrate (7) carrying a second electrode (6). The electrodes are disposed to face each other in spaced apart relationship, sandwiching a spacer (4) therebetween. A first cut-out portion extends through the first insulating substrate (1) and a spacer (4) to expose a first contact area (23) on the second insulating substrate (7). This permits the electrical contact means (31) to effect electrical connection with the first contact (23) which in turn is in electrically conductive connection with the second electrode (6). A similar contact arrangement may be disposed on the opposite side of the sensor.
摘要翻译: 本发明涉及适于与具有电接触装置(3)的电源电连接的传感器。 传感器具有承载第一电极(2)的第一绝缘基板(1)和承载第二电极(6)的第二绝缘基板(7)。 这些电极被设置为以间隔开的方式彼此面对,将间隔物(4)夹在其间。 第一切口部分延伸穿过第一绝缘基板(1)和间隔件(4)以暴露第二绝缘基板(7)上的第一接触区域(23)。 这允许电接触装置(31)实现与第一接触件(23)的电连接,第一触头(23)又与第二电极(6)导电连接。 类似的接触装置可以设置在传感器的相对侧上。
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公开(公告)号:US09791531B2
公开(公告)日:2017-10-17
申请号:US14231118
申请日:2014-03-31
申请人: Thomas Beck , Rainer Schneider
发明人: Thomas Beck , Rainer Schneider
CPC分类号: G01R33/543 , G01R33/243 , G01R33/246 , G01R33/583
摘要: A method for establishing a magnetic resonance system actuation sequence is described. A first number of field distribution maps are acquired for slices of the measurement region, and a radiofrequency pulse train is established on the basis thereof for the magnetic resonance system actuation sequence. This acquisition of the first number of field distribution maps may be brought about on the basis of an acquisition scheme. A reduced number of field distribution representation maps are established on the basis of the acquired field distribution maps, which field distribution representation maps represent the first number of acquired field distribution maps in accordance with a predetermined optimization criterion, and the radiofrequency pulse train is established on the basis of the field distribution representation maps.
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