公开(公告)号：US12104992B2

公开(公告)日：2024-10-01

申请号：US17274108

申请日：2019-07-31

Applicant: BIODYNE CO., LTD.

Inventor： Wook Bin Im ,  Jae Joon Lee ,  Moo Seong Shin

IPC: G01N1/28 ,  G01N1/40 ,  G01N35/00

CPC classification number: G01N1/2813 ,  G01N1/4077 ,  G01N35/00029 ,  G01N2001/4088 ,  G01N2035/00138 ,  G01N2035/00168

Abstract: The present invention relates to a technology related to an exfoliative cell processing device which obtains exfoliative cells out of a vial which has contained specimen of exfoliative cells (e.g., exfoliative cells and liquid medium) of a human body and then thinly smears the exfoliative cells on a cell smear slide. More specifically, the present invention relates to a technology for vertically entering the upper entrance of a vial which containing a specimen so as to extract a part of the specimen from the vial and then for thinly smearing the part of specimen on a cell smear slide which being disposed adjacent to the vial. The present invention has an advantage in that exfoliative cells may be attached in a thinly spread state on the lower surface of the specimen collector since the process of suctioning specimen from the vial.

公开(公告)号：US12085583B2

公开(公告)日：2024-09-10

申请号：US17319842

申请日：2021-05-13

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Michael Chen ,  Pey-Jiun Ko

IPC: G01N33/00 ,  B01L3/00 ,  B01L3/02 ,  B01L7/00 ,  B01L9/00 ,  B01L9/06 ,  C12Q1/42 ,  C12Q1/52 ,  C12Q1/6883 ,  C12Q1/70 ,  G01N15/1433 ,  G01N21/25 ,  G01N21/27 ,  G01N33/543 ,  G01N33/569 ,  G01N33/62 ,  G01N33/68 ,  G01N33/80 ,  G01N33/92 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10 ,  G01N15/01 ,  G01N15/10 ,  G01N15/14 ,  G01N33/50

CPC classification number: G01N35/0092 ,  B01L3/021 ,  B01L3/5027 ,  B01L3/5082 ,  B01L3/50855 ,  B01L7/52 ,  B01L9/06 ,  B01L9/543 ,  C12Q1/42 ,  C12Q1/52 ,  C12Q1/6883 ,  C12Q1/70 ,  G01N15/1433 ,  G01N21/25 ,  G01N21/27 ,  G01N33/54306 ,  G01N33/54313 ,  G01N33/54366 ,  G01N33/56972 ,  G01N33/56983 ,  G01N33/62 ,  G01N33/6827 ,  G01N33/80 ,  G01N33/92 ,  G01N35/00029 ,  G01N35/00069 ,  G01N35/00623 ,  G01N35/00871 ,  G01N35/026 ,  G01N35/04 ,  G01N35/10 ,  G01N35/1009 ,  G01N35/1011 ,  G01N35/1065 ,  G01N35/1072 ,  B01L9/52 ,  B01L2300/1827 ,  B01L2300/1855 ,  G01N2015/012 ,  G01N2015/016 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N33/5005 ,  G01N35/00 ,  G01N2035/00138 ,  G01N2035/00148 ,  G01N2035/00237 ,  G01N2035/00306 ,  G01N2035/00326 ,  G01N2035/00356 ,  G01N2035/00366 ,  G01N2035/00425 ,  G01N2035/00435 ,  G01N2035/00495 ,  G01N2035/00633 ,  G01N2035/0449 ,  G01N2035/0474 ,  G01N2035/0486 ,  G01N2035/0491 ,  G01N2035/0493 ,  G01N2035/0494 ,  G01N2201/024 ,  G01N2201/04 ,  G01N2201/12 ,  Y10T436/111666 ,  Y10T436/113332

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

公开(公告)号：US20240280596A1

公开(公告)日：2024-08-22

申请号：US18570626

申请日：2022-06-14

Applicant: RUBY ROBOTICS INC.

Inventor： Jeffrey SCHLOSSER ,  Daniel SHEN ,  Jeffery ALVAREZ ,  Christopher TACKLIND

IPC: G01N35/00 ,  B01L9/00 ,  G01N1/28 ,  G01N1/30 ,  G02B21/34

CPC classification number: G01N35/00029 ,  B01L9/52 ,  G01N1/2813 ,  G01N1/30 ,  G02B21/34 ,  B01L2200/025 ,  B01L2200/04 ,  B01L2300/041 ,  B01L2300/069 ,  B01L2300/0822 ,  G01N2035/00138

Abstract: The present disclosure provides systems, methods, and devices for sample processing. Sample processing may include rapid onsite evaluation of samples as well as additional types of sample processing. The sample processing methods and techniques provided herein facilitate consistent and rapid sample processing to obtain sample slides and sample images. The sample processing systems and devices provided herein facilitate the sample processing methods.

公开(公告)号：US20240255412A1

公开(公告)日：2024-08-01

申请号：US18633224

申请日：2024-04-11

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Kalyan Handique ,  Austin Payne ,  Vishal Sharma ,  Kyle Gleason ,  Priyadarshini Gogoi ,  Karthik Ganesan ,  Brian Boniface ,  William Chow

IPC: G01N15/14 ,  B01L3/00 ,  B01L3/02 ,  C12M1/00 ,  G01N1/20 ,  G01N1/28 ,  G01N1/40 ,  G01N15/01 ,  G01N15/10 ,  G01N15/1433 ,  G01N15/149 ,  G01N35/00 ,  G01N35/10 ,  G06V10/141 ,  G06V10/145 ,  G06V10/147 ,  G06V20/69

CPC classification number: G01N15/1484 ,  B01L3/502715 ,  B01L3/502761 ,  C12M47/04 ,  G01N1/20 ,  G01N1/28 ,  G01N1/40 ,  G01N1/405 ,  G01N1/4077 ,  G01N15/1433 ,  G01N35/00029 ,  G01N35/1011 ,  G06V10/141 ,  G06V10/145 ,  G06V10/147 ,  G06V20/69 ,  B01L3/021 ,  B01L3/502746 ,  B01L2200/0652 ,  B01L2200/0668 ,  B01L2300/0636 ,  B01L2300/0654 ,  B01L2300/0672 ,  B01L2300/0816 ,  B01L2300/0819 ,  B01L2300/0848 ,  B01L2300/0877 ,  B01L2300/168 ,  B01L2400/086 ,  G01N15/01 ,  G01N2015/1006 ,  G01N15/149 ,  G01N2035/00158 ,  G01N2035/1039

Abstract: A system and method for isolating and analyzing single cells, including: a substrate having a broad surface; a set of wells defined at the broad surface of the substrate, and a set of channels, defined by the wall, that fluidly couple each well to at least one adjacent well in the set of wells; and fluid delivery module defining an inlet and comprising a plate, removably coupled to the substrate, the plate defining a recessed region fluidly connected to the inlet and facing the broad surface of the substrate, the fluid delivery module comprising a cell capture mode.

公开(公告)号：US20240230697A1

公开(公告)日：2024-07-11

申请号：US18457364

申请日：2023-08-29

Applicant: SONG YI SYSTEM CO., LTD.

Inventor： Chun-Chieh CHIANG ,  Li-Ling CHANG

IPC: G01N35/00

CPC classification number: G01N35/0099 ,  G01N35/00029 ,  G01N35/00623 ,  G01N2035/00039 ,  G01N2035/00891

Abstract: A method of operating a slide information capturing and evaluation device includes receiving a slide in a first region of a slide cassette device. The slide is moved out of the first region of the slide cassette device and the slide is placed on an alignment device by a robotic arm. The slide is moved out of the alignment device and the slide is placed on an image capturing device by the robotic arm. An image of a sample distribution area of the slide is captured by the image capturing device. The slide is determined whether in a defective state based on the image captured by the image capturing device.

公开(公告)号：US20240183868A1

公开(公告)日：2024-06-06

申请号：US18072892

申请日：2022-12-01

Applicant: Rushabh Instruments, LLC

Inventor： Preyas Shah ,  Sahil Shah

IPC: G01N35/00

CPC classification number: G01N35/00029 ,  G01N2035/00138 ,  G01N2035/00346

Abstract: A laboratory slide heater includes a housing having an interior region defining a plurality of stations and an open end; a plurality of movable covers at least partially concealing the open end of the interior region; and a heater positioned to deliver heat into the interior region for heating one or more of the plurality of stations. Each movable cover is positioned to provide access to one station of the plurality of stations. The stations may be arranged in a circular fashion on a rotatable platform for drying purposes.

公开(公告)号：US20240124829A1

公开(公告)日：2024-04-18

申请号：US18399336

申请日：2023-12-28

Applicant: Copan Italia S.p.A.

Inventor： Daniele Triva

IPC: C12M1/36 ,  C12M1/00 ,  C12M1/22 ,  C12M1/26 ,  C12M1/34 ,  C12N1/20 ,  G01N35/00

CPC classification number: C12M41/48 ,  C12M23/10 ,  C12M23/50 ,  C12M23/52 ,  C12M33/00 ,  C12M41/06 ,  C12M41/46 ,  C12N1/20 ,  G01N35/00029 ,  G01N35/00732

Abstract: An automatic processing device of culture plates including a support frame; a slide for removably housing a culture plate and movably mounted on the support frame selectively displaceable between a first loading position, a plurality of image-acquiring positions, and a first unloading position; a camera of a linear type, provided with a telecentric optic and a trilinear sensor, and arranged to acquire a multiplicity of linear images of corresponding linear portions of an upper surface of the culture plate, during the displacing of the slide; a first lighting device orientated such as to illuminate the linear portions of an upper surface of the culture plate; an advancing device of the slide configured such as to enable obtaining a constant and substantially vibration-free advancing speed of the slide in the image-acquiring zone; and an electronic control device of a functioning of the camera, of the lighting device and of the advancing device.

公开(公告)号：US11958657B2

公开(公告)日：2024-04-16

申请号：US16499504

申请日：2018-03-28

Applicant: QIAGEN Healthcare Biotechnologies Systems GmbH

Inventor： Kathryn Louise Lamerton ,  Michael John Smith ,  Phillip Evans ,  Kristina Swann

IPC: B65D25/10 ,  B01L9/00 ,  G01N35/00

CPC classification number: B65D25/107 ,  B01L9/52 ,  G01N35/00029 ,  B01L2200/025 ,  B01L2300/0861 ,  G01N2035/00089 ,  G01N2035/00148

Abstract: Disclosed is a lidded magazine (100) for holding plural generally flat sample collection cards (10) in spaced parallel relation, the magazine is open at its top and includes upstanding opposed side walls (110,120), each wall (110,120) further including plural opposed pairs of inwardly extending wall ribs (112,122) spaced along each wall (110,120) to provide therebetween card accepting slots, a first slot dimension (W) being defined by the spacing between an interior face (154) of each wall, the magazine being characterised in that the walls (110,120) at the top (152) of each slot (150) are tapered outwardly such that the first dimension (W) is greatest at the top of the slot (150).

公开(公告)号：US11946926B2

公开(公告)日：2024-04-02

申请号：US16955014

申请日：2018-12-18

Applicant: BIO-RAD EUROPE GMBH

Inventor： Emmanuel Guignet ,  Stephane Bombard

IPC: G01N33/49 ,  B01L9/06 ,  G01N1/38 ,  G01N15/04 ,  G01N15/05 ,  G01N35/00

CPC classification number: G01N33/491 ,  B01L9/06 ,  G01N1/38 ,  G01N15/042 ,  G01N15/05 ,  G01N35/00029 ,  B01L2200/025 ,  B01L2300/0627 ,  G01N2015/047 ,  G01N2035/00148 ,  G01N2035/00495

Abstract: A method of testing a biological sample, the method comprising: providing a centrifuge sample holder having a camera; arranging a transparent container comprising a fluid test medium in a recess of said centrifuge sample holder, wherein the camera is arranged to image a portion of the container comprising said fluid test medium; arranging said biological sample above and not in contact with said fluid test medium in said container; and with the camera, imaging a mixing of said biological sample with said fluid test medium while centrifuging the sample holder.

公开(公告)号：US20240085442A1

公开(公告)日：2024-03-14

申请号：US18235272

申请日：2023-08-17

Applicant: Ventana Medical Systems, Inc. ,  Roche Molecular Systems, Inc.

Inventor： Meg E. Creasey ,  Matthew D. Mette ,  Denny Osswald ,  James E. Phillips-Portillo ,  Clayton Reynolds ,  Curtis C. Rose ,  Alexander Schmelzer ,  Franklin R. Ventura

IPC: G01N35/00

CPC classification number: G01N35/00029 ,  G01N35/0099

Abstract: A slide carrier includes: a base support; and a slide platform having a surface that is parallel to a first plane defined by a first vector and a second vector, wherein a vector extending in a direction opposite to the direction of gravity is normal with respect to a second plane defined by a third vector and a fourth vector, an angle between the first vector and the third vector is greater than zero degrees and less than 90 degrees, and an angle between the second vector and the fourth vector is greater than zero degrees and less than 90 degrees.