专利检索 ap:("Alberto Bargiotti" OR "Teresa Bordoni" OR "Pierangelo Zini" OR "Sergio Penco") AND inv:"Teresa Bordoni" 第 1 页

1.

发明授权
Antitumor anthracycline glycosides, intermediates thereof, and composition and use thereof 失效
标题翻译：抗癌蒽环类苷，其中间体及其组成和用途

公开(公告)号：US4839346A

公开(公告)日：1989-06-13

申请号：US101382

申请日：1987-09-28

申请人： Alberto Bargiotti , Teresa Bordoni , Pierangelo Zini , Sergio Penco

发明人： Alberto Bargiotti , Teresa Bordoni , Pierangelo Zini , Sergio Penco

IPC分类号： A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61P35/00 , A61P35/02 , C07H13/04 , C07H15/04 , C07H15/252

CPC分类号： C07H13/04 , C07H15/04 , C07H15/252

摘要： New anthracycline glycosides having formula: ##STR1## wherein R.sup.1 is hydrogen or hydroxy and either R.sup.2 or R.sup.3 is hydrogen with the other amino-methyl are described. The new compounds and their pharmaceutically acceptable addition salts are useful as antitumour agents.

摘要翻译： 描述了具有下式的新的蒽环类苷：其中R1是氢或羟基，R2或R3与另一个氨基甲基是氢。新化合物及其药学上可接受的加成盐可用作抗肿瘤剂。

2.

发明授权
New antitumor agent obtained by microbial stereoselective reduction of 4'-deoxy-4'-iododoxorubicin 失效
标题翻译：通过微生物立体选择性还原4'-脱氧-4'-碘代二恶霉素获得的新型抗肿瘤剂

公开(公告)号：US4895933A

公开(公告)日：1990-01-23

申请号：US145282

申请日：1988-01-19

申请人： Giuseppe Cassinelli , Teresa Bordoni , Sergio Merli , Giovanni Rivola

发明人： Giuseppe Cassinelli , Teresa Bordoni , Sergio Merli , Giovanni Rivola

IPC分类号： C12P19/56 , A61K20060101 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61P35/00 , C07G20060101 , C07H15/252 , C12P29/00 , C12R1/465

CPC分类号： C07H15/252 , Y10S435/886

摘要： 4'-Deoxy-13(S)-dihydro-4'-iododoxorubicin having the formula (II): ##STR1## and pharmaceutically acceptable salts thereof are anti-tumor agents.