公开(公告)号：US20240294650A1

公开(公告)日：2024-09-05

申请号：US17995189

申请日：2021-03-30

Applicant: Alector LLC

Inventor： Michael KURNELLAS ,  Santiago Viveros SALAZAR ,  Marina ROELL ,  Angie Grace YEE ,  Seung-Joo LEE ,  Tina SCHWABE ,  Maxime CHAPON ,  William Francis ESTACIO ,  Arnon ROSENTHAL

IPC: C07K16/28 ,  G01N33/573

CPC classification number: C07K16/2863 ,  G01N33/573 ,  C07K2317/33 ,  C07K2317/75 ,  C07K2317/76 ,  C07K2317/92 ,  G01N2333/9121

Abstract: The present disclosure is generally directed to antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a MerTK polypeptide, e.g. a mammalian MerTK or human MerTK, and use of such compositions in preventing, reducing risk, or treating a disease or disorder an individual in need thereof.

公开(公告)号：US20240287204A1

公开(公告)日：2024-08-29

申请号：US18392569

申请日：2023-12-21

Applicant: ALECTOR LLC

Inventor： Seung-Joo LEE ,  Spencer Liang ,  Angie YEE ,  Marina ROELL ,  Arnon ROSENTHAL

IPC: C07K16/40 ,  A61K39/00 ,  A61P35/00 ,  C07K16/28

CPC classification number: C07K16/40 ,  A61P35/00 ,  C07K16/2818 ,  C07K16/2827 ,  A61K2039/507 ,  C07K2317/56 ,  C07K2317/622 ,  C07K2317/76

Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a MerTK polypeptide, e.g., a mammalian MerTK or human MerTK, and use of such compositions in treating an individual in need thereof.

公开(公告)号：US20210261685A1

公开(公告)日：2021-08-26

申请号：US17118921

申请日：2020-12-11

Applicant: Alector LLC

Inventor： Seung-Joo LEE ,  Spencer LIANG ,  Angie YEE ,  Marina ROELL ,  Arnon ROSENTHAL

IPC: C07K16/40 ,  C07K16/28 ,  A61P35/00

Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a MerTK polypeptide, e.g., a mammalian MerTK or human MerTK, and use of such compositions in treating an individual in need thereof.