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1.发明申请公开(公告)号：US20170172742A1
公开(公告)日：2017-06-22
申请号：US15452435
申请日：2017-03-07
IPC分类号： A61F2/24
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/1214 , A61B17/12172 , A61B17/12195 , A61B2017/00243 , A61B2017/00557 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00601 , A61B2017/00615 , A61B2017/00632 , A61B2017/00867 , A61B2017/0649 , A61B2017/12095 , A61F2/2487 , A61F2210/0076 , A61F2250/0003
摘要： Partitioning devices that may be secured and sealed within a heart chamber for separating a patient's heart chamber into a productive portion and a non-productive portion are described herein. The partitioning devices described herein may include a membrane with a plurality of inflatable elements. The membrane may include a valve disposed in a central region of the membrane with a plurality of inflation channels extending radially from the valve. These devices may be secured within the heart chamber by sealing them to the wall of the heart chamber, for example, by inflating the plurality of inflatable elements on the periphery of the device. The non-productive portion may be filled with a material, including occlusive materials. Sealing and/or filling the non-productive portion formed by the devices described herein may help prevent leakage from the non-productive region.
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2.发明申请SYSTEM FOR IMPROVING CARDIAC FUNCTION BY SEALING A PARTITIONING MEMBRANE WITHIN A VENTRICLE 审中-公开通过密封隔离膜在心脏中改善心脏功能的系统公开(公告)号：US20130165735A1
公开(公告)日：2013-06-27
申请号：US13773235
申请日：2013-02-21
IPC分类号： A61F2/24
CPC分类号： A61F2/2487 , A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/1214 , A61B17/12172 , A61B17/12195 , A61B2017/00243 , A61B2017/00557 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00601 , A61B2017/00615 , A61B2017/00632 , A61B2017/00867 , A61B2017/0649 , A61B2017/12095
摘要： Partitioning devices that may be secured and sealed within a heart chamber for separating a patient's heart chamber into a productive portion and a non-productive portion are described herein. The partitioning devices described herein may include a reinforced membrane with outwardly biased members. The reinforced membrane may have a central hub with a distally extending support stem with a plurality of feet which extend radially from a centerline axis and preferably have ends that are aligned in a common plane. These devices may be secured within the heart chamber by sealing them to the wall of the heart chamber, for example, by inflating an inflatable element on the periphery of the device. The non-productive portion may be filled with a material, including occlusive materials. Sealing and/or filling the non-productive portion formed by the devices described herein may help prevent leakage from the non-productive region.
摘要翻译： 本文描述了可以在心室内固定和密封以将患者的心室分离成生产部分和非生产性部分的分隔装置。 本文所述的分隔装置可以包括具有向外偏置构件的增强膜。 增强膜可以具有中心毂，其具有远端延伸的支撑杆，其具有从中心线轴线径向延伸的多个脚，并且优选地具有在公共平面中对准的端部。 这些装置可以通过将它们密封到心室的壁来固定在心脏腔室内，例如通过使装置的周边上的可充气元件膨胀。 非生产性部分可以填充材料，包括封闭材料。 密封和/或填充由本文所述的装置形成的非生产性部分可以有助于防止从非生产性区域泄漏。
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公开(公告)号：US20150265405A1
公开(公告)日：2015-09-24
申请号：US14731161
申请日：2015-06-04
申请人： Michael P. BOUTILLETTE , James R. KERMODE , Miles D. ALEXANDER , Alexander KHAIRKHAHAN , Serjan D. NIKOLIC
发明人： Michael P. BOUTILLETTE , James R. KERMODE , Miles D. ALEXANDER , Alexander KHAIRKHAHAN , Serjan D. NIKOLIC
CPC分类号： A61F2/2487 , A61B17/00234 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00292 , A61B2017/00867 , A61B2017/12054 , A61B2017/12081 , A61B2017/12095 , A61F2230/0093 , A61M5/007 , A61M25/007
摘要： Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.
摘要翻译： 用于分配心脏心室的系统包括分隔装置或植入物，以及用于插入，重新定位和/或移除分隔装置的施用器。 植入物可以支撑心室壁并且可以减小心室的体积。 用于将分配装置递送和部署到心室的递送系统可以包括具有用于以折叠构造耦合到分隔装置的远端联接元件的导管; 导管还可以具有用于向分隔装置施加力以将其完全展开成展开构型并将其固定或密封抵靠心室壁的扩张构件。
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公开(公告)号：US20160302924A1
公开(公告)日：2016-10-20
申请号：US15133080
申请日：2016-04-19
申请人： Michael P. BOUTILLETTE , James R. KERMODE , Miles D. ALEXANDER , Alexander KHAIRKHAHAN , Serjan D. NIKOLIC
发明人： Michael P. BOUTILLETTE , James R. KERMODE , Miles D. ALEXANDER , Alexander KHAIRKHAHAN , Serjan D. NIKOLIC
CPC分类号： A61B90/39 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00526 , A61B2017/00867 , A61B2017/12054 , A61B2017/12095 , A61B2090/3966 , A61M25/09 , B29C43/18 , B29C65/18 , B29C66/1122 , B29C66/532 , B29C66/53261 , B29C66/545 , B29C66/636 , B29C66/71 , B29C66/712 , B29C66/727 , B29C66/729 , B29C66/81429 , B29C66/81431 , B29C66/8322 , B29C70/74 , B29L2031/753 , B29K2027/18 , B29K2023/06 , B29K2023/065
摘要： Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.
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公开(公告)号：US20140343356A1
公开(公告)日：2014-11-20
申请号：US14448778
申请日：2014-07-31
CPC分类号： A61F2/2487 , A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00575 , A61B2017/00592 , A61B2017/00615 , A61B2017/00632 , A61B2017/00867 , A61B2017/12095 , A61F2002/2484
摘要： Described herein are methods of treating a patient to prevent or correct cardiac remodeling following myocardial infarction. In general these methods may include inserting or implanting a device in a heart chamber to support the affected region within 72 hours after myocardial infarction. The device may be a support device (e.g., a resilient frame) and/or a partitioning device.
摘要翻译： 本文描述了治疗患者以预防或纠正心肌梗塞后的心脏重塑的方法。 通常，这些方法可以包括在心室中插入或植入装置以在心肌梗死后72小时内支持受影响的区域。 该装置可以是支撑装置（例如，弹性框架）和/或分隔装置。
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公开(公告)号：US20130338695A1
公开(公告)日：2013-12-19
申请号：US13973868
申请日：2013-08-22
IPC分类号： A61B17/00
CPC分类号： A61F2/2487 , A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00575 , A61B2017/00592 , A61B2017/00615 , A61B2017/00632 , A61B2017/00867 , A61B2017/12095 , A61F2002/2484
摘要： Described herein are methods of treating a patient to prevent or correct cardiac remodeling following myocardial infarction. In general these methods may include inserting or implanting a device in a heart chamber to support the affected region within 72 hours after myocardial infarction. The device may be a support device (e.g., a resilient frame) and/or a partitioning device.
摘要翻译： 本文描述了治疗患者以预防或纠正心肌梗塞后的心脏重塑的方法。 通常，这些方法可以包括在心室中插入或植入装置以在心肌梗死后72小时内支持受影响的区域。 该装置可以是支撑装置（例如，弹性框架）和/或分隔装置。
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公开(公告)号：US20130317537A1
公开(公告)日：2013-11-28
申请号：US13954221
申请日：2013-07-30
IPC分类号： A61B17/12
CPC分类号： A61F2/2427 , A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B17/3468 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00632 , A61B2017/00867 , A61B2017/0649 , A61B2017/12054 , A61B2017/12095 , A61F2/2487 , A61F2002/2484 , A61F2250/0003
摘要： Removable cardiac implants, applicators for inserting, repositioning and/or removing them, and methods of using them are described. In particular, removable or repositionable ventricular partitioning devices are described. Systems including removable implants and applicators for inserting and/or removing them are also described.
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公开(公告)号：US20150209144A1
公开(公告)日：2015-07-30
申请号：US14681930
申请日：2015-04-08
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B17/3468 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00632 , A61B2017/00867 , A61B2017/0649 , A61B2017/12054 , A61B2017/12095 , A61F2/2487 , A61F2002/2484 , A61F2250/0003
摘要： Removable cardiac implants, applicators for inserting, repositioning and/or removing them, and methods of using them are described. In particular, removable or repositionable ventricular partitioning devices are described. Systems including removable implants and applicators for inserting and/or removing them are also described.
摘要翻译： 描述了可移除的心脏植入物，用于插入，重新定位和/或去除它们的施用器以及使用它们的方法。 特别地，描述了可拆卸或可重新定位的心室分配装置。 还描述了包括用于插入和/或移除它们的可移除植入物和施用器的系统。
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公开(公告)号：US20120158111A1
公开(公告)日：2012-06-21
申请号：US13331922
申请日：2011-12-20
申请人： Alexander KHAIRKHAHAN , Alan OSTROFF , Eric VARADY , Paul PASPA
发明人： Alexander KHAIRKHAHAN , Alan OSTROFF , Eric VARADY , Paul PASPA
IPC分类号： A61N1/05
CPC分类号： A61N1/37205 , A61N1/057 , A61N1/0573 , A61N1/375 , A61N1/3756
摘要： A leadless cardiac pacemaker having a radial fixation mechanism is provided. The cardiac pacemaker can include fixation mechanism separate from a pacing electrode and having a diameter equal to or less than the outer diameter of the pacemaker. The fixation mechanism can allow the pacemaker to be inserted into tissue with less than 2 rotations of the pacemaker to place the pacing electrode in contact with the tissue. In some embodiments, the fixation mechanism can comprise a plurality of hooks or protrusions positioned near a distal portion of the pacemaker. The fixation mechanism(s) can be configured to penetrate the endocardium of the patient and reside mostly within the myocardium. Methods of delivering the leadless cardiac pacemaker into the heart are also provided.
摘要翻译： 提供具有径向固定机构的无引线心脏起搏器。 心脏起搏器可以包括与起搏电极分离并具有等于或小于起搏器的外径的直径的固定机构。 固定机构可以允许起搏器以小于2转的起搏器插入组织中以使起搏电极与组织接触。 在一些实施例中，固定机构可以包括定位在起搏器远侧部分附近的多个钩或突起。 固定机制可被配置成穿透患者的心内膜并且主要驻留在心肌内。 还提供了将无引导心脏起搏器送入心脏的方法。
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