公开(公告)号：US20140066968A1

公开(公告)日：2014-03-06

申请号：US14075698

申请日：2013-11-08

Applicant: Allergan, Inc.

Inventor： Elizabeta Pavlovic ,  Jordan Thompson ,  Loantrang Dang ,  Alexei Goraltchouk

IPC: A61F5/00

CPC classification number: A61F5/003 ,  A61F5/0036 ,  A61L31/042 ,  A61L31/048 ,  A61L31/06 ,  A61L31/14 ,  C08L79/02 ,  C08L67/04 ,  C08L1/28 ,  C08L5/08 ,  C08L23/16

Abstract: An intragastric balloon with a 12-month lifespan. The intragastric balloon has a shell made of a material with as good as or better than initial mechanical properties of previous materials; i.e. higher ultimate tensile strength (UTS) and elongation at break (Eb), lower stiffness (K), higher acid stability, and improved resistance to infection. The new materials in particular provide improved acid resistance. These new materials produce a device that has reduced adverse events and a longer lifespan in vivo. The materials may form the entire wall of the shell or may form just a barrier layer coupled with a scaffold layer of a different material.

Abstract translation: 一个12个月的寿命的胃内气球。 胃内球囊具有由先前材料的初始机械性能好或优于原材料的材料制成的外壳; 即更高的极限拉伸强度（UTS）和断裂伸长率（Eb），较低的刚度（K），较高的酸稳定性和改善的抗感染性。 新材料特别提供改善的耐酸性。 这些新材料产生的体内减少不良事件和更长使用寿命的装置。 材料可以形成壳的整个壁，或者可以形成仅与不同材料的支架层结合的阻挡层。

公开(公告)号：US20130053956A1

公开(公告)日：2013-02-28

申请号：US13659803

申请日：2012-10-24

Applicant: ALLERGAN, INC.

Inventor： Thomas Powell ,  Loantrang Dang

IPC: A61F2/12

CPC classification number: A61F2/12 ,  A61F2/0077 ,  A61F2002/0086

Abstract: A method of texturing a soft prosthetic implant shell, such as a silicone breast implant shell. A soft prosthetic implant with a textured external surface layer of silicone elastomer and having an open-cell structure is made by adhering and then dissolving round salt crystals. The resulting roughened surface has enhanced physical properties relative to surfaces formed with angular salt crystals. An implant having such a textured external surface layer is expected to help prevent capsular contraction, to help prevent scar formation, and to help in anchoring the implant within the body.

公开(公告)号：US09138310B2

公开(公告)日：2015-09-22

申请号：US13659803

申请日：2012-10-24

Applicant: Allergan, Inc.

Inventor： Thomas Powell ,  Loantrang Dang

IPC: A61F2/12 ,  A61F2/00

CPC classification number: A61F2/12 ,  A61F2/0077 ,  A61F2002/0086

Abstract: A method of texturing a soft prosthetic implant shell, such as a silicone breast implant shell. A soft prosthetic implant with a textured external surface layer of silicone elastomer and having an open-cell structure is made by adhering and then dissolving round salt crystals. The resulting roughened surface has enhanced physical properties relative to surfaces formed with angular salt crystals. An implant having such a textured external surface layer is expected to help prevent capsular contraction, to help prevent scar formation, and to help in anchoring the implant within the body.

Abstract translation: 软质假体植入物外壳的纹理化方法，例如硅树脂乳房植入物壳。 通过粘附然后溶解圆形盐晶体来制造具有有机硅弹性体的织构化外表面层并具有开孔结构的软假体植入物。 所得到的粗糙表面相对于用角盐晶体形成的表面具有增强的物理性能。 期望具有这样有纹理的外表面层的植入物有助于防止荚膜收缩，以帮助防止瘢痕形成，并有助于将植入物锚固在体内。