-
1.Highly purified mocarhagin, a cobra venom protease, polynucleotides encoding same and related proteases, and therapeutic uses thereof 失效
标题翻译: 高度纯化的莫卡金,眼镜蛇毒蛋白酶,编码相关蛋白酶的多核苷酸及其治疗用途公开(公告)号:US06881404B2
公开(公告)日:2005-04-19
申请号:US09996620
申请日:2001-11-27
申请人: Amechand Boodhoo , Jasbir S. Seehra , Gray Shaw , Dianne Sako
发明人: Amechand Boodhoo , Jasbir S. Seehra , Gray Shaw , Dianne Sako
CPC分类号: A61K38/4886 , C12N9/6418
摘要: Highly purified mocarhagin, a cobra venom protease, is disclosed. Pharmaceutical compositions and therapeutic uses of the highly purified protease are also provided. Polynucleotides encoding such protease and related proteases are also disclosed.
摘要翻译: 公开了高纯度的莫卡金,眼镜蛇毒蛋白酶。 还提供了高纯度蛋白酶的药物组合物和治疗用途。 还公开了编码这种蛋白酶和相关蛋白酶的多核苷酸。
-
2.Highly purified mocarhagin, a cobra venom protease, polynucleotides encoding same and related proteases, and therapeutic uses thereof 失效
标题翻译: 高度纯化的莫卡金,眼镜蛇毒蛋白酶,编码相关蛋白酶的多核苷酸及其治疗用途公开(公告)号:US07252820B2
公开(公告)日:2007-08-07
申请号:US11066236
申请日:2005-02-25
申请人: Amechand Boodhoo , Jasbir S. Seehra , Gray Shaw , Dianne Sako
发明人: Amechand Boodhoo , Jasbir S. Seehra , Gray Shaw , Dianne Sako
CPC分类号: A61K38/4886 , C12N9/6418
摘要: Methods and compositions for treating a wide range of inflammatory diseases and disorders, and for inhibiting selectin-mediated binding by administering a mocarhagin protein, or fragments thereof with mocarhagin protein activity are provided. The mocarhagin protein may be administered alone, or in combination with a cytokine, lymphokine, or hematopoietic factor.
摘要翻译: 提供了用于治疗多种炎性疾病和病症的方法和组合物,并且通过施用莫卡海明蛋白或其片段具有莫卡宾蛋白活性来抑制选择素介导的结合。 莫卡海明蛋白可以单独施用或与细胞因子,淋巴因子或造血因子组合施用。
-
3.Highly purified mocarhagin cobra venom protease polynucleotides endcoding same and related proteases and therapeutic uses thereof 失效
标题翻译: 末端编码相同的蛋白酶及其治疗用途的高度纯化的莫卡列奇眼镜蛇毒蛋白多核苷酸公开(公告)号:US06413760B1
公开(公告)日:2002-07-02
申请号:US09026001
申请日:1998-02-18
申请人: Amechand Boodhoo , Jasbir S. Seehra , Gray Shaw , Dianne Sako
发明人: Amechand Boodhoo , Jasbir S. Seehra , Gray Shaw , Dianne Sako
IPC分类号: C12N964
CPC分类号: A61K38/4886 , C12N9/6418
摘要: Highly purified mocarhagin, a cobra venom protease, is disclosed. Pharmaceutical compositions and therapeutic uses of the highly purified protease are also provided. Polynucleotides encoding such protease and related proteases are also disclosed.
摘要翻译: 公开了高纯度的莫卡金,眼镜蛇毒蛋白酶。 还提供了高纯度蛋白酶的药物组合物和治疗用途。 还公开了编码这种蛋白酶和相关蛋白酶的多核苷酸。
-
4.Highly purified mocarhagin, a cobra venom protease, polynucleotides encoding same and related proteases, and therapeutic uses thereof 失效
标题翻译: 高度纯化的莫卡金,眼镜蛇毒蛋白酶,编码相关蛋白酶的多核苷酸及其治疗用途公开(公告)号:US20050232914A1
公开(公告)日:2005-10-20
申请号:US11066236
申请日:2005-02-25
申请人: Amechand Boodhoo , Jasbir Seehra , Gray Shaw , Dianne Sako
发明人: Amechand Boodhoo , Jasbir Seehra , Gray Shaw , Dianne Sako
CPC分类号: A61K38/4886 , C12N9/6418
摘要: Methods and compositions for treating a wide range of inflammatory diseases and disorders, and for inhibiting selectin-mediated binding by administering a mocarhagin protein, or fragments thereof with mocarhagin protein activity are provided. The mocarhagin protein may be administered alone, or in combination with a cytokine, lymphokine, or hematopoietic factor.
摘要翻译: 提供了用于治疗广泛的炎性疾病和病症以及通过施用莫卡英蛋白或其片段具有莫卡宾蛋白活性来抑制选择素介导的结合的方法和组合物。 莫卡海明蛋白可以单独施用或与细胞因子,淋巴因子或造血因子组合施用。
-
5.PLATELET GLYCOPROTEIN IB ALPHA VARIANT FUSION POLYPEPTIDES AND METHODS OF USE THEREOF 审中-公开
标题翻译: PLATELET GLYCOPROTEIN IB ALPHA VARIANT FUSION POLYPEPTIDES及其使用方法公开(公告)号:US20110039780A1
公开(公告)日:2011-02-17
申请号:US12621887
申请日:2009-11-19
申请人: Gray Shaw , Dianne Sako , Ravindra Kumar , Jin Xu
发明人: Gray Shaw , Dianne Sako , Ravindra Kumar , Jin Xu
CPC分类号: C07K14/705 , A61K38/00 , C07K2319/00
摘要: The present invention provides compositions and methods for treating or preventing vascular-associated disorders.
摘要翻译: 本发明提供了用于治疗或预防血管相关疾病的组合物和方法。
-
6.Platelet glycoprotein Ib alpha variant fusion polypeptides and methods of use thereof 失效
标题翻译: 血小板糖蛋白Ibα变体融合多肽及其使用方法公开(公告)号:US07727535B2
公开(公告)日:2010-06-01
申请号:US10868371
申请日:2004-06-14
申请人: Gray Shaw , Dianne Sako , Ravindra Kumar , Jin Xu
发明人: Gray Shaw , Dianne Sako , Ravindra Kumar , Jin Xu
CPC分类号: C07K14/705 , A61K38/00 , C07K2319/00
摘要: The present invention provides compositions and methods for treating or preventing vascular-associated disorders.
摘要翻译: 本发明提供了用于治疗或预防血管相关疾病的组合物和方法。
-
7.Platelet glycoprotein Ib alpha variant fusion polypeptides and methods of use thereof 失效
标题翻译: 血小板糖蛋白Ibα变体融合多肽及其使用方法公开(公告)号:US20050089888A1
公开(公告)日:2005-04-28
申请号:US10868371
申请日:2004-06-14
申请人: Gray Shaw , Dianne Sako , Ravindra Kumar , Jin Xu
发明人: Gray Shaw , Dianne Sako , Ravindra Kumar , Jin Xu
IPC分类号: A61K38/00 , A61K38/36 , C07K14/705 , C07K14/745 , C12N15/12 , C12Q1/68 , C07H21/04 , C12N9/22
CPC分类号: C07K14/705 , A61K38/00 , C07K2319/00
摘要: The present invention provides compositions and methods for treating or preventing vascular-associated disorders.
摘要翻译: 本发明提供了用于治疗或预防血管相关疾病的组合物和方法。
-
公开(公告)号:US20060140935A1
公开(公告)日:2006-06-29
申请号:US11257579
申请日:2005-10-24
申请人: Gray Shaw , Dianne Sako , Ravindra Kumar , Francis Sullivan , Tom McDonagh
发明人: Gray Shaw , Dianne Sako , Ravindra Kumar , Francis Sullivan , Tom McDonagh
IPC分类号: A61K39/395 , C07K16/40
CPC分类号: C07K14/705 , A61K38/1709 , C07K2319/00
摘要: The present invention provides compositions and methods for treating or preventing vascular-associated disorders.
-
9.Platelet glycoprotein Ib alpha fusion polypeptides and methods of use thereof 审中-公开
标题翻译: 血小板糖蛋白Ibα融合多肽及其使用方法公开(公告)号:US20060093614A1
公开(公告)日:2006-05-04
申请号:US11257581
申请日:2005-10-24
申请人: Gray Shaw , Dianne Sako , Ravindra Kumar , Francis Sullivan , Tom McDonagh
发明人: Gray Shaw , Dianne Sako , Ravindra Kumar , Francis Sullivan , Tom McDonagh
IPC分类号: A61K39/00 , C07H21/04 , C12P21/04 , C07K14/705
CPC分类号: C07K14/705 , A61K38/1709 , C07K2319/00
摘要: The present invention provides compositions and methods for treating or preventing vascular-associated disorders.
摘要翻译: 本发明提供了用于治疗或预防血管相关疾病的组合物和方法。
-
-
-
-
-
-
-
-