公开(公告)号：US11753386B2

公开(公告)日：2023-09-12

申请号：US17272031

申请日：2019-08-30

Applicant: Amgen, Inc.

Inventor： Sebastien Caille ,  Michael Corbett ,  Austin Smith

IPC: C07D263/14 ,  C07D211/76

CPC classification number: C07D263/14 ,  C07D211/76 ,  C07B2200/13

Abstract: The present invention provides commercial processes for preparing 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid as well as intermediates thereof.

公开(公告)号：US20230379796A1

公开(公告)日：2023-11-23

申请号：US18363661

申请日：2023-08-01

Applicant: Amgen, Inc.

Inventor： Sebastien Caille ,  Michael Corbett ,  Austin Smith

IPC: H04W48/04 ,  H04W76/38 ,  H04W48/08

CPC classification number: H04W48/04 ,  H04W76/38 ,  H04W48/08

Abstract: The present invention provides commercial processes for preparing 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid as well as intermediates thereof.

公开(公告)号：US20210347743A1

公开(公告)日：2021-11-11

申请号：US17272031

申请日：2019-08-30

Applicant: Amgen, Inc.

Inventor： Sebastien Caille ,  Michael Corbett ,  Austin Smith

IPC: C07D263/14 ,  C07D211/76

Abstract: The present invention provides commercial processes for preparing 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3- yl)acetic acid as well as intermediates thereof.