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1.发明申请公开(公告)号：US20200071738A1
公开(公告)日：2020-03-05
申请号：US16676340
申请日：2019-11-06
Applicant: Amgen Inc.
Inventor： Sohye KANG , Chung HUANG, JR. , Hedieh BARKHORDARIAN , Pavel BONDARENKO , Zhongqi ZHANG
Abstract: The present invention relates to a method for manipulating the high mannose glycoform content of recombinant glycoproteins by regulating ornithine metabolism during cell culture.
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