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公开(公告)号:US07858626B2
公开(公告)日:2010-12-28
申请号:US11830024
申请日:2007-07-30
申请人: Amogh Boloor , Mui Cheung , Ronda Gayle Davis-Ward , Philip Anthony Harris , Kevin Hinkle , Christopher P. Lauderman , Robert Anthony Mook, Jr. , Jeffery Alan Stafford , James Marvin Veal
发明人: Amogh Boloor , Mui Cheung , Ronda Gayle Davis-Ward , Philip Anthony Harris , Kevin Hinkle , Christopher P. Lauderman , Robert Anthony Mook, Jr. , Jeffery Alan Stafford , James Marvin Veal
IPC分类号: C07D403/04 , A61K31/53 , A61P35/00
CPC分类号: C07D239/30 , C07D231/56 , C07D235/08 , C07D403/12 , C07D413/14
摘要: Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译: 本文描述了可用作VEGFR2抑制剂的嘧啶衍生物。 所述的发明还包括制备此类嘧啶衍生物的方法以及使用该嘧啶衍生物的方法来治疗过度增殖性疾病。