公开(公告)号：US11382900B2

公开(公告)日：2022-07-12

申请号：US16805202

申请日：2020-02-28

申请人： AMOREPACIFIC CORPORATION

发明人： Gyeyoung Choi ,  Hyunjin Nam ,  Miyoung Park ,  Kyoungmi Jung ,  Jihae Lee ,  Chang Soon Choi ,  Youngho Park ,  Jong Hwa Roh ,  Eunsil Park ,  Jaehong Park ,  Kwanghyun Shin ,  Byoung Young Woo ,  Kiwha Lee ,  Wonkyung Cho ,  Joonho Choi

IPC分类号： A61K31/44 ,  A61K9/00 ,  A61K9/06

摘要： Disclosed is a method for preventing or treating sleep disorders using TRPV1 receptor antagonist, (R)—N-[1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide. The method of the present invention can effectively and safely prevent or treat sleep disorders accompanying pruritus caused by atopic dermatitis.

公开(公告)号：US11998633B2

公开(公告)日：2024-06-04

申请号：US17289382

申请日：2019-10-16

申请人： Amorepacific Corporation

发明人： Wonkyung Cho ,  Kwanghyun Shin ,  Joonho Choi ,  Kiwha Lee ,  Jong Hwa Roh ,  Miyoung Park ,  Youngho Park ,  Eunsil Park ,  Jaehong Park ,  Byoung Young Woo ,  Min Soo Kim ,  Eun Sol Ha

IPC分类号： A61K9/08 ,  A61K9/06 ,  A61K31/44 ,  A61K47/10 ,  A61K47/26 ,  A61K47/32 ,  A61K47/38 ,  A61K9/00

CPC分类号： A61K9/06 ,  A61K31/44 ,  A61K47/10 ,  A61K47/26 ,  A61K47/32 ,  A61K47/38 ,  A61K9/0014

摘要： One aspect of the present disclosure relates to a sol-gel composition enabling reversible sol-gel transition and, more specifically, to a sol-gel composition of which the viscosity changes by external physical force so that reversible sol-gel transition is performed.

公开(公告)号：US12059412B2

公开(公告)日：2024-08-13

申请号：US16976140

申请日：2019-03-21

申请人： Amorepacific Corporation

发明人： Joonho Choi ,  Wonkyung Cho ,  Jong Hwa Roh ,  Kwanghyun Shin ,  Byoung Young Woo ,  Min Soo Kim ,  Miyoung Park ,  Youngho Park ,  Eunsil Park ,  Jaehong Park ,  Kiwha Lee

IPC分类号： A61K31/44 ,  A61K9/00 ,  A61K31/79 ,  A61K47/32

CPC分类号： A61K31/44 ,  A61K9/0014 ,  A61K47/32

摘要： One aspect of the present disclosure relates to a pharmaceutical composition, containing (R)-N-[1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide as a first ingredient and containing a vinylpyrrolidone-based polymer as a second ingredient. The composition of one aspect of the present disclosure has a formulation characteristic in which the crystal formation of a compound represented by chemical formula 1 is delayed for a long time.

公开(公告)号：US11878008B2

公开(公告)日：2024-01-23

申请号：US16805381

申请日：2020-02-28

申请人： AMOREPACIFIC CORPORATION

发明人： Gyeyoung Choi ,  Hyunjin Nam ,  Miyoung Park ,  Kyoungmi Jung ,  Jihae Lee ,  Chang Soon Choi ,  Youngho Park ,  Jong Hwa Roh ,  Eunsil Park ,  Jaehong Park ,  Kwanghyun Shin ,  Byoung Young Woo ,  Kiwha Lee ,  Wonkyung Cho ,  Joonho Choi

IPC分类号： A61P17/04 ,  A61K31/44 ,  A61K9/00

CPC分类号： A61K31/44 ,  A61K9/0014 ,  A61P17/04

摘要： Disclosed is a method for preventing or treating atopic dermatitis using TRPV1 receptor antagonist. More specifically, it may be possible to prevent and/or treat the atopic dermatitis without any side effects such as an increase in body temperature, epidermal atrophy, and the like by percutaneously administrating a composition for external use on the skin containing the TRPV1 receptor antagonist.