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公开(公告)号：US11998633B2
公开(公告)日：2024-06-04
申请号：US17289382
申请日：2019-10-16
发明人： Wonkyung Cho , Kwanghyun Shin , Joonho Choi , Kiwha Lee , Jong Hwa Roh , Miyoung Park , Youngho Park , Eunsil Park , Jaehong Park , Byoung Young Woo , Min Soo Kim , Eun Sol Ha
摘要： One aspect of the present disclosure relates to a sol-gel composition enabling reversible sol-gel transition and, more specifically, to a sol-gel composition of which the viscosity changes by external physical force so that reversible sol-gel transition is performed.
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公开(公告)号：US11653665B2
公开(公告)日：2023-05-23
申请号：US16997591
申请日：2020-08-19
发明人： Kwanghyun Shin , Wonkyung Cho , Jinoh Chung , Yong Deog Hong
摘要： Shown are a particulate processed product of tea and a method for preparing the same. The particulate processed product of tea has a sphericity S10 value of a particle corresponding to 10% cumulative subdistribution in cumulative distribution measured for the sphericity of tea particles of 0.68 or greater. The processed product of tea is convenient to drink because it is readily wetted and dispersed in water. In addition, it can be easily packaged and used due to a low angle of repose and thus excellent flowability.
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公开(公告)号：US11612172B2
公开(公告)日：2023-03-28
申请号：US16664272
申请日：2019-10-25
发明人： Kwanghyun Shin , Wonkyung Cho , Jinoh Chung , Yong Deog Hong
摘要： The present disclosure shows a particulate processed product of tea with quick dispersibility in water and a method for manufacturing a particulate processed product of tea. The processed product of tea comprises 20% by weight or less of fine powders having a particle diameter of 75 μm or less based on the total weight of the tea particles. The manufacturing method comprises the step of manufacturing tea particles using a fluid-bed rotor granulator having a rotor disc. The processed product of tea has quick wettability and dispersibility in water and thus is easy to drink. Also, the processed product of tea has a low angle of repose and thus has excellent flowability, so that it is easy to pack and use.
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公开(公告)号：US11382900B2
公开(公告)日：2022-07-12
申请号：US16805202
申请日：2020-02-28
发明人： Gyeyoung Choi , Hyunjin Nam , Miyoung Park , Kyoungmi Jung , Jihae Lee , Chang Soon Choi , Youngho Park , Jong Hwa Roh , Eunsil Park , Jaehong Park , Kwanghyun Shin , Byoung Young Woo , Kiwha Lee , Wonkyung Cho , Joonho Choi
摘要： Disclosed is a method for preventing or treating sleep disorders using TRPV1 receptor antagonist, (R)—N-[1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide. The method of the present invention can effectively and safely prevent or treat sleep disorders accompanying pruritus caused by atopic dermatitis.
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公开(公告)号：US10034815B2
公开(公告)日：2018-07-31
申请号：US14358035
申请日：2012-11-13
发明人： Changman Park , Sungwon Yi , Changkeun Lee , Kwanghyun Shin , Taehong Shin , Seunghwan Yi , Taekjin Oh , Byungyoung Kang
CPC分类号： A61H23/02 , A61F7/02 , A61F7/034 , A61H2201/0207 , A61H2201/0228 , A61H2201/165 , A61K9/7038 , A61N1/0408 , A61N1/0472 , A61N1/0492 , A61N1/32
摘要： The present invention includes a flexible main body; a drug layer attached to a bottom surface of the main body and formed of an additive mixed with a drug and formed of anti-inflammatory analgesic drugs; a vibrating module attached on a top surface of the main body and including a vibration motor and a battery; and a plurality of legs installed along the perimeter of the main body and being adhesive. Through this configuration in which the main body is formed of a flexible material, and the plurality of legs are adhesive and are attached along the perimeter of the main body, the vibrating stimulus pad may be easily attached on an unwell body region to which attachment is difficult such as a joint region.
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![Pharmaceutical composition containing (R)-N-[1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethylpyridin-3-yl)-acrylamide and method for inhibiting crystal formation thereof](/abs-image/US/2024/08/13/US12059412B2/abs.jpg.150x150.jpg)
公开(公告)号：US12059412B2
公开(公告)日：2024-08-13
申请号：US16976140
申请日：2019-03-21
发明人： Joonho Choi , Wonkyung Cho , Jong Hwa Roh , Kwanghyun Shin , Byoung Young Woo , Min Soo Kim , Miyoung Park , Youngho Park , Eunsil Park , Jaehong Park , Kiwha Lee
CPC分类号： A61K31/44 , A61K9/0014 , A61K47/32
摘要： One aspect of the present disclosure relates to a pharmaceutical composition, containing (R)-N-[1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide as a first ingredient and containing a vinylpyrrolidone-based polymer as a second ingredient. The composition of one aspect of the present disclosure has a formulation characteristic in which the crystal formation of a compound represented by chemical formula 1 is delayed for a long time.
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公开(公告)号：US11878008B2
公开(公告)日：2024-01-23
申请号：US16805381
申请日：2020-02-28
发明人： Gyeyoung Choi , Hyunjin Nam , Miyoung Park , Kyoungmi Jung , Jihae Lee , Chang Soon Choi , Youngho Park , Jong Hwa Roh , Eunsil Park , Jaehong Park , Kwanghyun Shin , Byoung Young Woo , Kiwha Lee , Wonkyung Cho , Joonho Choi
CPC分类号： A61K31/44 , A61K9/0014 , A61P17/04
摘要： Disclosed is a method for preventing or treating atopic dermatitis using TRPV1 receptor antagonist. More specifically, it may be possible to prevent and/or treat the atopic dermatitis without any side effects such as an increase in body temperature, epidermal atrophy, and the like by percutaneously administrating a composition for external use on the skin containing the TRPV1 receptor antagonist.
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公开(公告)号：US20140309563A1
公开(公告)日：2014-10-16
申请号：US14358035
申请日：2012-11-13
发明人： Changman Park , Sungwon Yi , Changkeun Lee , Kwanghyun Shin , Taehong Shin , Seunghwan Yi , Taekjin Oh , Byungyoung Kang
CPC分类号： A61H23/02 , A61F7/02 , A61F7/034 , A61H2201/0207 , A61H2201/0228 , A61H2201/165 , A61K9/7038 , A61N1/0408 , A61N1/0472 , A61N1/0492 , A61N1/32
摘要： The present disclosure relates to a vibrating stimulus pad configured to easily attach to an unwell body region to which attachment is difficult such as a joint region. The vibrating stimulus pad of the present disclosure includes: a flexible main body; a drug layer attached to a bottom surface of the main body and formed of an additive mixed with a drug and formed of anti-inflammatory analgesic drugs; a vibrating module attached on a top surface of the main body and including a vibration motor and a battery; and a plurality of legs installed along the perimeter of the main body and being adhesive. Through this configuration in which the main body is formed of a flexible material, and the plurality of legs are adhesive and are attached along the perimeter of the main body, the vibrating stimulus pad may be easily attached on an unwell body region to which attachment is difficult such as a joint region.
摘要翻译： 本公开涉及一种振动刺激垫，其被配置为容易地附接到诸如接合区域的难以附着的不适的身体区域。 本公开的振动刺激垫包括：柔性主体; 药物层，其附着于主体的底面，由与药物混合形成的由消炎止痛药形成的添加剂形成; 振动模块，其安装在所述主体的顶表面上并且包括振动马达和电池; 以及沿着主体的周边安装并且是粘合剂的多个腿。 通过这种构造，其中主体由柔性材料形成，并且多个腿部是粘合剂并且沿着主体的周边安装，振动刺激垫可以容易地附接到不适于身体的区域，附着物 困难如联合地区。
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