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公开(公告)号：US07871642B2
公开(公告)日：2011-01-18
申请号：US11446844
申请日：2006-06-05
CPC分类号： A61K9/1075 , A61K9/4858 , A61K9/4866 , Y10S514/846 , Y10S514/937 , Y10S514/938 , Y10S514/941 , Y10S514/947
摘要： A nanodispersion comprises (a) a membrane-forming molecule, (b) a coemulsifier and (c) a lipophilic component, in pharmaceutical end formulations, the nanodispersion being obtainable by (α) mixing the components (a), (b) and (c) until a homogeneous clear liquid is obtained, and (β) adding the liquid obtained in step (α) to the water phase of the pharmaceutical end formulations, where steps (α) and (β) may be carried out without high energy mixing or homogenization. The nanodispersions prepared according to this invention are suitable as transport vehicles for pharmaceutical active agents.
摘要翻译： 纳米分散体包含（a）在药物末端制剂中的成膜分子（b）共乳化剂和（c）亲脂性组分，所述纳米分散体可通过（α）混合组分（a），（b）和（ c）直到获得均匀的透明液体，并且将（步骤（α）中获得的液体）添加到药物末端制剂的水相中，其中步骤（α）和（＆bgr）可以在不高的情况下进行 能量混合或均质化。 根据本发明制备的纳米分散体适合用作药物活性剂的运输工具。
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公开(公告)号：US07008638B2
公开(公告)日：2006-03-07
申请号：US10016903
申请日：2001-12-14
CPC分类号： A61K8/04 , A61K8/553 , A61K8/68 , A61K2800/21 , A61Q1/02 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/10 , B82Y5/00
摘要： A description is given of the use of a nanodispersion, which comprises (a) a membrane-forming molecule, (b) a coemulsifier and (c) a lipophilic component, in cosmetic end formulation, which nanodispersion is obtainable by (α) mixing the components (a), (b) and (c) until a homogeneous clear liquid is obtained, and (β) adding the liquid obtained in step (α) to the water phase of the cosmetic end formulations, steps (α) and (β) being carried out without any additional supply of energy. The nanodispersions used according to this invention can be easily prepared and are suitable as carrier systems for a very wide range of cosmetic active agents and oil-soluble dyes.
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公开(公告)号：US07381423B2
公开(公告)日：2008-06-03
申请号：US11103208
申请日：2005-04-11
CPC分类号： A61K8/553 , A61K8/04 , A61K2800/413 , A61Q1/02 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/10 , B82Y5/00 , Y10S514/937 , Y10S514/938
摘要： A description is given of the use of a nanodispersion, which comprises (a) a membrane-forming molecule, (b) a coemulsifier and (c) a lipophilic component, in cosmetic end formulation, which nanodispersion is obtainable by (α) mixing the components (a), (b) and (c) until a homogeneous clear liquid is obtained, and (β) adding the liquid obtained in, step (α) to the water phase of the cosmetic end formulations, steps (α) and (β) being carried out without any additional supply of energy. The nanodispersions used according to this invention can be easily prepared and are suitable as carrier systems for a very wide range of cosmetic active agents and oil-soluble dyes.
摘要翻译： 描述了纳米分散体的使用，其包括（a）成膜分子，（b）化妆品末端制剂中的共乳化剂和（c）亲脂性组分，所述纳米分散体可通过（α）将 组分（a），（b）和（c），直到获得均匀的透明液体，和（β）将在步骤（α）中获得的液体加入到化妆品末端制剂的水相中，步骤（α）和 beta）在没有任何额外的能量供应的情况下进行。 根据本发明使用的纳米分散体可以容易地制备并且适合作为用于非常宽范围的美容活性剂和油溶性染料的载体体系。
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公开(公告)号：US07081253B2
公开(公告)日：2006-07-25
申请号：US09306006
申请日：1999-05-06
CPC分类号： A61K9/1075 , A61K9/4858 , A61K9/4866 , Y10S514/846 , Y10S514/937 , Y10S514/938 , Y10S514/941 , Y10S514/947
摘要： A description is given of the use of a nanodispersion, which comprises (a) a membrane-forming molecule, (b) a coemulsifier and (c) a lipophilic component, in pharmaceutical end formulations, the nanodispersion being obtainable by (α) mixing the components (a), (b) and (c) until a homogeneous clear liquid is obtained, and (β) adding the liquid obtained in step (α) to the water phase of the pharmaceutical end formulations, steps (α) and (β) being carried out without any additional supply of energy. The nanodispersions used according to this invention are suitable as transport vehicles for pharmaceutical active agents.
摘要翻译： 给出了使用纳米分散体的描述，该纳米分散体包含（a）在药物末端制剂中的成膜分子，（b）共乳化剂和（c）亲脂性组分，纳米分散体可通过（α）混合 组分（a），（b）和（c），直到获得均匀的透明液体，和（β）将步骤（α）中获得的液体加入到药物末端制剂的水相中，步骤（α）和 ）在没有任何额外的能量供应的情况下进行。 根据本发明使用的纳米分散体适合用作药物活性剂的运输载体。
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公开(公告)号：US20050191330A1
公开(公告)日：2005-09-01
申请号：US11103208
申请日：2005-04-11
CPC分类号： A61K8/553 , A61K8/04 , A61K2800/413 , A61Q1/02 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/10 , B82Y5/00 , Y10S514/937 , Y10S514/938
摘要： A description is given of the use of a nanodispersion, which comprises (a) a membrane-forming molecule, (b) a coemulsifier and (c) a lipophilic component, in cosmetic end formulation, which nanodispersion is obtainable by (α) mixing the components (a), (b) and (c) until a homogeneous clear liquid is obtained, and (β) adding the liquid obtained in, step (α) to the water phase of the cosmetic end formulations, steps (α) and (β) being carried out without any additional supply of energy. The nanodispersions used according to this invention can be easily prepared and are suitable as carrier systems for a very wide range of cosmetic active agents and oil-soluble dyes.
摘要翻译： 描述了纳米分散体的使用，其包括（a）成膜分子，（b）化妆品末端制剂中的共乳化剂和（c）亲脂性组分，所述纳米分散体可通过（α）将 组分（a），（b）和（c），直到获得均匀的透明液体，和（β）将在步骤（α）中获得的液体加入到化妆品末端制剂的水相中，步骤（α）和 beta）在没有任何额外的能量供应的情况下进行。 根据本发明使用的纳米分散体可以容易地制备并且适合作为用于非常宽范围的美容活性剂和油溶性染料的载体体系。
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