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    METHOD OF DETECTING FLUORESCENCE
    6.
    发明申请
    METHOD OF DETECTING FLUORESCENCE 有权
    检测荧光的方法

    公开(公告)号：US20110060150A1

    公开(公告)日：2011-03-10

    申请号：US12853755

    申请日：2010-08-10

    申请人： Andrei Laikhter ,  Mark Aaron Behlke ,  Yawfui Yong ,  Scott Rose ,  Lingyan Huang

    发明人： Andrei Laikhter ,  Mark Aaron Behlke ,  Yawfui Yong ,  Scott Rose ,  Lingyan Huang

    IPC分类号： C07C50/18 ,  C07F9/06

    CPC分类号： C07H21/00 ,  C07C225/36 ,  C07F9/091 ,  C07F9/2408 ,  C09B1/325 ,  C12Q1/6818

    摘要： The invention provides novel anthraquinone compositions that are useful as broad-spectrum quenchers of fluorescence and provides methods for making and using them. The anthraquinone quenchers can be conjugated to a variety of biologically relevant compounds, including lipids, nucleic acids, polypeptides, and more specifically antigens, steroids, vitamins, drugs, haptens, metabolites, toxins, environmental pollutants, amino acids, peptides, proteins, nucleotides, oligonucleotides, polynucleotides, carbohydrates, and their analogs. The invention also provides kits comprising, in one or more containers, at least one anthraquinone quencher dye composition of the present invention, and instructions for using that composition.

    摘要翻译： 本发明提供了新颖的蒽醌组合物，其可用作荧光的广谱猝灭剂，并提供制备和使用它们的方法。 蒽醌猝灭剂可以与各种生物相关化合物缀合，包括脂质，核酸，多肽，更具体地，抗原，类固醇，维生素，药物，半抗原，代谢物，毒素，环境污染物，氨基酸，肽，蛋白质，核苷酸 ，寡核苷酸，多核苷酸，碳水化合物及其类似物。 本发明还提供在一个或多个容器中包含至少一种本发明的蒽醌猝灭剂染料组合物的试剂盒，以及使用该组合物的说明书。

    Di-alpha amino anthraquinone compositions
    7.
    发明授权
    Di-alpha amino anthraquinone compositions 有权
    二-α氨基蒽醌组合物

    公开(公告)号：US08114979B2

    公开(公告)日：2012-02-14

    申请号：US12853755

    申请日：2010-08-10

    申请人： Andrei Laikhter ,  Mark Aaron Behlke ,  Yawfui Yong ,  Scott Rose ,  Lingyan Huang

    发明人： Andrei Laikhter ,  Mark Aaron Behlke ,  Yawfui Yong ,  Scott Rose ,  Lingyan Huang

    IPC分类号： C07H21/04 ,  C07C45/27

    CPC分类号： C07H21/00 ,  C07C225/36 ,  C07F9/091 ,  C07F9/2408 ,  C09B1/325 ,  C12Q1/6818

    摘要： The invention provides novel anthraquinone compositions that are useful as broad-spectrum quenchers of fluorescence and provides methods for making and using them. The anthraquinone quenchers can be conjugated to a variety of biologically relevant compounds, including lipids, nucleic acids, polypeptides, and more specifically antigens, steroids, vitamins, drugs, haptens, metabolites, toxins, environmental pollutants, amino acids, peptides, proteins, nucleotides, oligonucleotides, polynucleotides, carbohydrates, and their analogs. The invention also provides kits comprising, in one or more containers, at least one anthraquinone quencher dye composition of the present invention, and instructions for using that composition.

    摘要翻译： 本发明提供了新颖的蒽醌组合物，其可用作荧光的广谱猝灭剂，并提供制备和使用它们的方法。 蒽醌猝灭剂可以与各种生物相关化合物缀合，包括脂质，核酸，多肽，更具体地，抗原，类固醇，维生素，药物，半抗原，代谢物，毒素，环境污染物，氨基酸，肽，蛋白质，核苷酸 ，寡核苷酸，多核苷酸，碳水化合物及其类似物。 本发明还提供在一个或多个容器中包含至少一种本发明的蒽醌猝灭剂染料组合物的试剂盒，以及使用该组合物的说明书。

    Methods of detecting fluorescence with anthraquinone quencher dyes
    8.
    发明授权
    Methods of detecting fluorescence with anthraquinone quencher dyes 有权
    用蒽醌猝灭剂染料检测荧光的方法

    公开(公告)号：US07803536B2

    公开(公告)日：2010-09-28

    申请号：US10666998

    申请日：2003-09-19

    申请人： Mark Aaron Behlke ,  Lingyan Huang ,  Andrei Laikhter ,  Yawfui Yong ,  Scott Rose

    发明人： Mark Aaron Behlke ,  Lingyan Huang ,  Andrei Laikhter ,  Yawfui Yong ,  Scott Rose

    IPC分类号： C12Q1/68 ,  C07C45/27

    CPC分类号： C07H21/00 ,  C07C225/36 ,  C07F9/091 ,  C07F9/2408 ,  C09B1/325 ,  C12Q1/6818

    摘要： The invention provides novel anthraquinone compositions that are useful as broad-spectrum quenchers of fluorescence and provides methods for making and using them. The anthraquinone quenchers can be conjugated to a variety of biologically relevant compounds, including lipids, nucleic acids, polypeptides, and more specifically antigens, steroids, vitamins, drugs, haptens, metabolites, toxins, environmental pollutants, amino acids, peptides, proteins, nucleotides, oligonucleotides, polynucleotides, carbohydrates, and their analogs. The invention also provides kits comprising, in one or more containers, at least one anthraquinone quencher dye composition of the present invention, and instructions for using that composition.

    摘要翻译： 本发明提供了新颖的蒽醌组合物，其可用作荧光的广谱猝灭剂，并提供制备和使用它们的方法。 蒽醌猝灭剂可以与各种生物相关化合物缀合，包括脂质，核酸，多肽，更具体地，抗原，类固醇，维生素，药物，半抗原，代谢物，毒素，环境污染物，氨基酸，肽，蛋白质，核苷酸 ，寡核苷酸，多核苷酸，碳水化合物及其类似物。 本发明还提供在一个或多个容器中包含至少一种本发明的蒽醌猝灭剂染料组合物的试剂盒，以及使用该组合物的说明书。