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公开(公告)号：US08728562B2
公开(公告)日：2014-05-20
申请号：US12949638
申请日：2010-11-18
申请人： Kimberly A. Morris , Andrew De Kock , David A. Durand , Joshua Haarer , Ronald W. Kunkel , Peter J. Wolf , Joel T. Eggert , Joseph A. Cihlar
发明人： Kimberly A. Morris , Andrew De Kock , David A. Durand , Joshua Haarer , Ronald W. Kunkel , Peter J. Wolf , Joel T. Eggert , Joseph A. Cihlar
CPC分类号： A61N1/05
摘要： A method of manufacturing a medical electrical lead includes molding a lead body pre-form, stringing an electrode onto the pre-form and overmolding the pre-form with a polymer to form a lead body portion. The pre-form has a proximal end, a distal end and at least one lumen extending between the proximal and distal ends. At least one asymmetric region of the pre-form has a transverse cross-section that has a non-circular outer dimension. The overmolding causes the asymmetric region to become substantially circular.
摘要翻译： 制造医用电线的方法包括将引线体预成型件模制成型，将电极引导到预成型件上，并用聚合物包覆模制预成型件以形成引线本体部分。 预成型件具有近端，远端和在近端和远端之间延伸的至少一个内腔。 预成型体的至少一个非对称区域具有非圆形外部尺寸的横截面。 包覆成型导致不对称区域变得基本上是圆形的。
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公开(公告)号：US20110160831A1
公开(公告)日：2011-06-30
申请号：US12905633
申请日：2010-10-15
IPC分类号： A61N1/05
CPC分类号： A61N1/0568 , B29C45/02 , B29C45/14311 , B29C45/14598 , B29C45/1671 , B29C67/246 , B29L2031/753
摘要： A medical electrical lead includes a tapered distal tip having a tapered drug-eluting component incorporated therein. The drug-eluting component can be an overmolded drug-eluting collar or a pre-molded drug eluting collar. The drug-eluting collar is disposed in a recess formed in the tapered distal tip and maintains the overall tapered profile of the distal tip.
摘要翻译： 医用电引线包括锥形的远端尖端，其具有结合在其中的锥形药物洗脱组分。 药物洗脱组分可以是包覆成型的药物洗脱颈圈或预成型药物洗脱颈圈。 药物洗脱颈圈设置在形成在锥形远端尖端中的凹部中，并保持远侧末端的整体锥形轮廓。
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公开(公告)号：US20110160825A1
公开(公告)日：2011-06-30
申请号：US12979911
申请日：2010-12-28
申请人： Joshua Haarer , Yevgeniya Shvelidze , Patrick Willoughby , Andrew De Kock , Kimberly A. Morris , Benjamin J. Haasl , Brian L. Schmidt , Emilio Abner Aviles Delgado , Fabian E. Morales Ortiz , Ronald W. Kunkel
发明人： Joshua Haarer , Yevgeniya Shvelidze , Patrick Willoughby , Andrew De Kock , Kimberly A. Morris , Benjamin J. Haasl , Brian L. Schmidt , Emilio Abner Aviles Delgado , Fabian E. Morales Ortiz , Ronald W. Kunkel
CPC分类号： H01R43/20 , A61N1/056 , A61N1/0587 , A61N2001/0585 , Y10T29/49117 , Y10T29/49218
摘要： Various coiled conductors having two or more sections and methods and devices for constructing such conductors are disclosed. The various embodiments of coiled conductors and related methods include two or more sections that can have different mechanical, structural, and/or electrical characteristics.
摘要翻译： 公开了具有两个或多个部分的各种线圈导体以及用于构造这种导体的方法和装置。 线圈导体和相关方法的各种实施例包括可以具有不同机械，结构和/或电特性的两个或多个部分。
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公开(公告)号：US08527067B2
公开(公告)日：2013-09-03
申请号：US12905633
申请日：2010-10-15
IPC分类号： A61N1/05
CPC分类号： A61N1/0568 , B29C45/02 , B29C45/14311 , B29C45/14598 , B29C45/1671 , B29C67/246 , B29L2031/753
摘要： A medical electrical lead includes a tapered distal tip having a tapered drug-eluting component incorporated therein. The drug-eluting component can be an overmolded drug-eluting collar or a pre-molded drug eluting collar. The drug-eluting collar is disposed in a recess formed in the tapered distal tip and maintains the overall tapered profile of the distal tip.
摘要翻译： 医用电引线包括锥形的远端尖端，其具有结合在其中的锥形药物洗脱组分。 药物洗脱组分可以是包覆成型的药物洗脱颈圈或预成型药物洗脱颈圈。 药物洗脱颈圈设置在形成在锥形远端尖端中的凹部中，并保持远侧末端的整体锥形轮廓。
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公开(公告)号：US08494651B2
公开(公告)日：2013-07-23
申请号：US12979911
申请日：2010-12-28
申请人： Joshua Hearer , Yevgeniya Shvelidze , Patrick Willoughby , Andrew De Kock , Kimberly A. Morris , Benjamin J. Haasl , Brian L. Schmidt , Emilio Aviles , Fabian Morales , Ronald W. Kunkel
发明人： Joshua Hearer , Yevgeniya Shvelidze , Patrick Willoughby , Andrew De Kock , Kimberly A. Morris , Benjamin J. Haasl , Brian L. Schmidt , Emilio Aviles , Fabian Morales , Ronald W. Kunkel
IPC分类号： A61N1/00
CPC分类号： H01R43/20 , A61N1/056 , A61N1/0587 , A61N2001/0585 , Y10T29/49117 , Y10T29/49218
摘要： Various coiled conductors having two or more sections and methods and devices for constructing such conductors are disclosed. The various embodiments of coiled conductors and related methods include two or more sections that can have different mechanical, structural, and/or electrical characteristics.
摘要翻译： 公开了具有两个或多个部分的各种线圈导体以及用于构造这种导体的方法和装置。 线圈导体和相关方法的各种实施例包括可以具有不同机械，结构和/或电特性的两个或多个部分。
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公开(公告)号：US20110160830A1
公开(公告)日：2011-06-30
申请号：US12953094
申请日：2010-11-23
申请人： Kimberly A. Morris , Eduardo Carlo Lopez , Andrew De Kock , Joel Grover , Joshua Haarer , Timothy R. Jackson , Ronald W. Kunkel , David R. Wulfman
发明人： Kimberly A. Morris , Eduardo Carlo Lopez , Andrew De Kock , Joel Grover , Joshua Haarer , Timothy R. Jackson , Ronald W. Kunkel , David R. Wulfman
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： Implantable electrical leads including an axial reinforcement member are disclosed. In some embodiments, an implantable electrical lead can have a body, one or more electrodes, a cable conductor, a conductor coil, and a reinforcement member. A cable conductor can be disposed within the body and is configured to convey electrical signals between the proximal region and the distal region of the lead. The reinforcement member may be coupled to or integrally formed within the lead body and is configured to limit elongation of the lead body in response to a tensile force.
摘要翻译： 公开了包括轴向加强构件的可植入电引线。 在一些实施例中，可植入电引线可以具有主体，一个或多个电极，电缆导体，导体线圈和加强构件。 电缆导体可以设置在主体内并且构造成在导线的近端区域和远端区域之间传送电信号。 加强构件可以联接到引线本体内或整体地形成在引线主体内，并且被配置为限制引线本体响应于拉伸力的伸长。
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公开(公告)号：US20110160823A1
公开(公告)日：2011-06-30
申请号：US12959010
申请日：2010-12-02
CPC分类号： A61N1/056 , B29C33/40 , B29C45/37 , B29L2031/753
摘要： A method of reducing a coefficient of friction between a medical electrical lead and a delivery system includes machining a mold for a lead, roughening at least a portion of the mold to an average surface roughness of at least about 7 micro-inches and injecting a polymer into the roughened mold to form a roughened portion of a lead body.
摘要翻译： 降低医用电引线与输送系统之间的摩擦系数的方法包括机加工用于引线的模具，将模具的至少一部分粗糙化至至少约7微英寸的平均表面粗糙度，并注入聚合物 进入粗糙的模具中以形成引线体的粗糙部分。
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公开(公告)号：US20110156306A1
公开(公告)日：2011-06-30
申请号：US12949638
申请日：2010-11-18
申请人： Kimberly A. Morris , Andrew De Kock , David A. Durand , Joshua Haarer , Ronald W. Kunkel , Peter Wolf , Joel Eggert , Joseph Cihlar
发明人： Kimberly A. Morris , Andrew De Kock , David A. Durand , Joshua Haarer , Ronald W. Kunkel , Peter Wolf , Joel Eggert , Joseph Cihlar
IPC分类号： B29C39/10
CPC分类号： A61N1/05
摘要： A method of manufacturing a medical electrical lead includes molding a lead body pre-form, stringing an electrode onto the pre-form and overmolding the pre-form with a polymer to form a lead body portion. The pre-form has a proximal end, a distal end and at least one lumen extending between the proximal and distal ends. At least one asymmetric region of the pre-form has a transverse cross-section that has a non-circular outer dimension. The overmolding causes the asymmetric region to become substantially circular.
摘要翻译： 制造医用电线的方法包括将引线体预成型件模制成型，将电极引导到预成型件上，并用聚合物包覆模制预成型件以形成引线本体部分。 预成型件具有近端，远端和在近端和远端之间延伸的至少一个内腔。 预成型体的至少一个非对称区域具有非圆形外部尺寸的横截面。 包覆成型导致不对称区域变得基本上是圆形的。
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9.发明授权公开(公告)号：US08983622B2
公开(公告)日：2015-03-17
申请号：US12939803
申请日：2010-11-04
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0573
摘要： Medical lead body configurations that reduce conductor flexural fatigue. The various lead body embodiments include a support section and can also include other features such as a semi-straight portion of a lumen or semi-straight sides that optimize the reduction in conductor flexural fatigue.
摘要翻译： 医疗铅体结构，可减少导体弯曲疲劳。 各种引线体实施例包括支撑部分，并且还可以包括优化导体弯曲疲劳减少的其他特征，例如管腔或半直边的半直线部分。
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10.发明申请公开(公告)号：US20110160819A1
公开(公告)日：2011-06-30
申请号：US12939803
申请日：2010-11-04
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0573
摘要： The embodiments herein relate to medical lead body configurations that reduce conductor flexural fatigue. The various lead body embodiments include a support section and can also include other features such as a semi-straight portion of a lumen or semi-straight sides that optimize the reduction in conductor flexural fatigue.
摘要翻译： 本文的实施例涉及减少导体弯曲疲劳的医疗引线体结构。 各种引线体实施例包括支撑部分，并且还可以包括优化导体弯曲疲劳减少的其他特征，例如管腔或半直边的半直线部分。
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