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1.发明授权MRI conditionally safe lead with low-profile multi-layer conductor for longitudinal expansion 有权MRI有条件安全的导线，带有用于纵向膨胀的低剖面多层导体公开(公告)号：US08391994B2
公开(公告)日：2013-03-05
申请号：US12940489
申请日：2010-11-05
申请人： Arthur J. Foster , Christopher Perrey , Stephen Earl DeRoche , Timothy R. Jackson , Andrew De Kock
发明人： Arthur J. Foster , Christopher Perrey , Stephen Earl DeRoche , Timothy R. Jackson , Andrew De Kock
IPC分类号： A61N1/05
CPC分类号： A61N1/08 , A61N1/05 , A61N1/056 , A61N1/086 , A61N1/3718 , A61N1/3925
摘要： An implantable electrical lead having a flexible body and including a multi-layer coil conductor extending within the longitudinal body lumen from the connector assembly to at least the electrode, the multi-layer coil conductor including a first coil layer a second coil layer disposed about the first coil layer, wherein at least one parameter of the first and the second coil layer is configured such that the lead exhibits a predetermined axial stiffness or bending stiffness.
摘要翻译： 一种可植入电引线，其具有柔性主体并且包括在纵向体腔内从连接器组件延伸至至少电极的多层线圈导体，多层线圈导体包括第一线圈层，第二线圈层围绕 第一线圈层，其中第一和第二线圈层的至少一个参数被构造成使得引线具有预定的轴向刚度或弯曲刚度。
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2.发明申请公开(公告)号：US20110160828A1
公开(公告)日：2011-06-30
申请号：US12940489
申请日：2010-11-05
申请人： Arthur J. Foster , Christopher Perrey , Stephen Earl DeRoche , Timothy R. Jackson , Andrew De Kock
发明人： Arthur J. Foster , Christopher Perrey , Stephen Earl DeRoche , Timothy R. Jackson , Andrew De Kock
IPC分类号： A61N1/05
CPC分类号： A61N1/08 , A61N1/05 , A61N1/056 , A61N1/086 , A61N1/3718 , A61N1/3925
摘要： An implantable electrical lead having a flexible body and including a multi-layer coil conductor extending within the longitudinal body lumen from the connector assembly to at least the electrode, the multi-layer coil conductor including a first coil layer a second coil layer disposed about the first coil layer, wherein at least one parameter of the first and the second coil layer is configured such that the lead exhibits a predetermined axial stiffness or bending stiffness.
摘要翻译： 一种可植入电引线，其具有柔性主体并且包括在纵向体腔内从连接器组件延伸至至少电极的多层线圈导体，多层线圈导体包括第一线圈层，第二线圈层围绕 第一线圈层，其中第一和第二线圈层的至少一个参数被构造成使得引线具有预定的轴向刚度或弯曲刚度。
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3.发明授权公开(公告)号：US08983622B2
公开(公告)日：2015-03-17
申请号：US12939803
申请日：2010-11-04
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0573
摘要： Medical lead body configurations that reduce conductor flexural fatigue. The various lead body embodiments include a support section and can also include other features such as a semi-straight portion of a lumen or semi-straight sides that optimize the reduction in conductor flexural fatigue.
摘要翻译： 医疗铅体结构，可减少导体弯曲疲劳。 各种引线体实施例包括支撑部分，并且还可以包括优化导体弯曲疲劳减少的其他特征，例如管腔或半直边的半直线部分。
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公开(公告)号：US08728562B2
公开(公告)日：2014-05-20
申请号：US12949638
申请日：2010-11-18
申请人： Kimberly A. Morris , Andrew De Kock , David A. Durand , Joshua Haarer , Ronald W. Kunkel , Peter J. Wolf , Joel T. Eggert , Joseph A. Cihlar
发明人： Kimberly A. Morris , Andrew De Kock , David A. Durand , Joshua Haarer , Ronald W. Kunkel , Peter J. Wolf , Joel T. Eggert , Joseph A. Cihlar
CPC分类号： A61N1/05
摘要： A method of manufacturing a medical electrical lead includes molding a lead body pre-form, stringing an electrode onto the pre-form and overmolding the pre-form with a polymer to form a lead body portion. The pre-form has a proximal end, a distal end and at least one lumen extending between the proximal and distal ends. At least one asymmetric region of the pre-form has a transverse cross-section that has a non-circular outer dimension. The overmolding causes the asymmetric region to become substantially circular.
摘要翻译： 制造医用电线的方法包括将引线体预成型件模制成型，将电极引导到预成型件上，并用聚合物包覆模制预成型件以形成引线本体部分。 预成型件具有近端，远端和在近端和远端之间延伸的至少一个内腔。 预成型体的至少一个非对称区域具有非圆形外部尺寸的横截面。 包覆成型导致不对称区域变得基本上是圆形的。
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5.发明申请公开(公告)号：US20100125320A1
公开(公告)日：2010-05-20
申请号：US12607806
申请日：2009-10-28
申请人： Jeannette C. Polkinghorne , Joseph A. Cihlar , Mitchell L. Horn-Wyffels , Joseph J. Nelsen , Raymond Gessler , Erin K. Webb , Joseph J. Schachtner , Arienne P. Simon , Andrew De Kock
发明人： Jeannette C. Polkinghorne , Joseph A. Cihlar , Mitchell L. Horn-Wyffels , Joseph J. Nelsen , Raymond Gessler , Erin K. Webb , Joseph J. Schachtner , Arienne P. Simon , Andrew De Kock
摘要： The various embodiments disclosed herein relate to medical electrical leads. More specifically, certain embodiments relate to leads having one or more drug-eluting components that are overmolded or otherwise positioned on the lead. Other embodiments relate to leads having one or more patterned surfaces, including some leads with one or more patterned surfaces over which one or more drug-eluting components are positioned. Further implementations relate to leads having one or more overmolded patterned surfaces, including some embodiments in which the overmolded surfaces contain at least one drug-eluting component.
摘要翻译： 本文公开的各种实施例涉及医疗电引线。 更具体地，某些实施方案涉及具有一种或多种药物洗脱组分的引线，所述药物洗脱组分被包覆成型或以其他方式定位在引线上。 其它实施方案涉及具有一个或多个图案化表面的引线，包括具有一个或多个图案化表面的一些引线，一个或多个药物洗脱组分位于该图案表面上。 进一步的实施方式涉及具有一个或多个包覆成型的图案化表面的引线，包括其中包覆成型的表面含有至少一种药物洗脱组分的一些实施方案。
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6.发明授权公开(公告)号：US08463399B2
公开(公告)日：2013-06-11
申请号：US12607806
申请日：2009-10-28
申请人： Jeannette C. Polkinghorne , Joseph A. Cihlar , Mitchell L. Horn-Wyffels , Joseph J. Nelsen , Raymond Gessler , Erin K. Webb , Joseph J. Schachtner , Arienne P. Simon , Andrew De Kock
发明人： Jeannette C. Polkinghorne , Joseph A. Cihlar , Mitchell L. Horn-Wyffels , Joseph J. Nelsen , Raymond Gessler , Erin K. Webb , Joseph J. Schachtner , Arienne P. Simon , Andrew De Kock
IPC分类号： A61N1/05
摘要： The various embodiments disclosed herein relate to medical electrical leads. More specifically, certain embodiments relate to leads having one or more drug-eluting components that are overmolded or otherwise positioned on the lead. Other embodiments relate to leads having one or more patterned surfaces, including some leads with one or more patterned surfaces over which one or more drug-eluting components are positioned. Further implementations relate to leads having one or more overmolded patterned surfaces, including some embodiments in which the overmolded surfaces contain at least one drug-eluting component.
摘要翻译： 本文公开的各种实施例涉及医疗电引线。 更具体地，某些实施方案涉及具有一种或多种药物洗脱组分的引线，所述药物洗脱组分被包覆成型或以其他方式定位在引线上。 其它实施方案涉及具有一个或多个图案化表面的引线，包括具有一个或多个图案化表面的一些引线，一个或多个药物洗脱组分位于该图案表面上。 进一步的实施方式涉及具有一个或多个包覆成型的图案化表面的引线，包括其中包覆成型的表面含有至少一种药物洗脱组分的一些实施方案。
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公开(公告)号：US20110160831A1
公开(公告)日：2011-06-30
申请号：US12905633
申请日：2010-10-15
IPC分类号： A61N1/05
CPC分类号： A61N1/0568 , B29C45/02 , B29C45/14311 , B29C45/14598 , B29C45/1671 , B29C67/246 , B29L2031/753
摘要： A medical electrical lead includes a tapered distal tip having a tapered drug-eluting component incorporated therein. The drug-eluting component can be an overmolded drug-eluting collar or a pre-molded drug eluting collar. The drug-eluting collar is disposed in a recess formed in the tapered distal tip and maintains the overall tapered profile of the distal tip.
摘要翻译： 医用电引线包括锥形的远端尖端，其具有结合在其中的锥形药物洗脱组分。 药物洗脱组分可以是包覆成型的药物洗脱颈圈或预成型药物洗脱颈圈。 药物洗脱颈圈设置在形成在锥形远端尖端中的凹部中，并保持远侧末端的整体锥形轮廓。
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公开(公告)号：US20110160825A1
公开(公告)日：2011-06-30
申请号：US12979911
申请日：2010-12-28
申请人： Joshua Haarer , Yevgeniya Shvelidze , Patrick Willoughby , Andrew De Kock , Kimberly A. Morris , Benjamin J. Haasl , Brian L. Schmidt , Emilio Abner Aviles Delgado , Fabian E. Morales Ortiz , Ronald W. Kunkel
发明人： Joshua Haarer , Yevgeniya Shvelidze , Patrick Willoughby , Andrew De Kock , Kimberly A. Morris , Benjamin J. Haasl , Brian L. Schmidt , Emilio Abner Aviles Delgado , Fabian E. Morales Ortiz , Ronald W. Kunkel
CPC分类号： H01R43/20 , A61N1/056 , A61N1/0587 , A61N2001/0585 , Y10T29/49117 , Y10T29/49218
摘要： Various coiled conductors having two or more sections and methods and devices for constructing such conductors are disclosed. The various embodiments of coiled conductors and related methods include two or more sections that can have different mechanical, structural, and/or electrical characteristics.
摘要翻译： 公开了具有两个或多个部分的各种线圈导体以及用于构造这种导体的方法和装置。 线圈导体和相关方法的各种实施例包括可以具有不同机械，结构和/或电特性的两个或多个部分。
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9.发明申请公开(公告)号：US20110160819A1
公开(公告)日：2011-06-30
申请号：US12939803
申请日：2010-11-04
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0573
摘要： The embodiments herein relate to medical lead body configurations that reduce conductor flexural fatigue. The various lead body embodiments include a support section and can also include other features such as a semi-straight portion of a lumen or semi-straight sides that optimize the reduction in conductor flexural fatigue.
摘要翻译： 本文的实施例涉及减少导体弯曲疲劳的医疗引线体结构。 各种引线体实施例包括支撑部分，并且还可以包括优化导体弯曲疲劳减少的其他特征，例如管腔或半直边的半直线部分。
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公开(公告)号：US08527067B2
公开(公告)日：2013-09-03
申请号：US12905633
申请日：2010-10-15
IPC分类号： A61N1/05
CPC分类号： A61N1/0568 , B29C45/02 , B29C45/14311 , B29C45/14598 , B29C45/1671 , B29C67/246 , B29L2031/753
摘要： A medical electrical lead includes a tapered distal tip having a tapered drug-eluting component incorporated therein. The drug-eluting component can be an overmolded drug-eluting collar or a pre-molded drug eluting collar. The drug-eluting collar is disposed in a recess formed in the tapered distal tip and maintains the overall tapered profile of the distal tip.
摘要翻译： 医用电引线包括锥形的远端尖端，其具有结合在其中的锥形药物洗脱组分。 药物洗脱组分可以是包覆成型的药物洗脱颈圈或预成型药物洗脱颈圈。 药物洗脱颈圈设置在形成在锥形远端尖端中的凹部中，并保持远侧末端的整体锥形轮廓。
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