公开(公告)号：US20060240048A1

公开(公告)日：2006-10-26

申请号：US10528613

申请日：2003-09-25

申请人： Andrew Eatherton ,  Gerard Martin Giblin ,  Richard Green ,  Jennifer Doughty ,  Karamjit Jandu ,  William Mitchell ,  Alan Naylor ,  Giovanni Palombi ,  Derek Rawlings ,  Brian Slingsby ,  Andrew Whittington

发明人： Andrew Eatherton ,  Gerard Martin Giblin ,  Richard Green ,  Jennifer Doughty ,  Karamjit Jandu ,  William Mitchell ,  Alan Naylor ,  Giovanni Palombi ,  Derek Rawlings ,  Brian Slingsby ,  Andrew Whittington

IPC分类号： A61K47/00

CPC分类号： C07D213/82 ,  C07D401/06 ,  C07D403/06 ,  C07D405/12 ,  C07D409/12

摘要： The present invention relates to novel pyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.

摘要翻译： 本发明涉及新颖的吡啶衍生物，含有这些化合物的药物组合物及其在治疗疾病尤其是疼痛中的用途，所述疾病通过大麻素受体的活性的增加或减少而直接或间接引起。

公开(公告)号：US20070129367A1

公开(公告)日：2007-06-07

申请号：US10528592

申请日：2003-09-25

申请人： Andrew Eatherton ,  Gerard Giblin ,  Richard Green ,  Jennifer Doughty ,  Karamjit Jandu ,  William Mitchell ,  Alan Naylor ,  Giovanni Palombi ,  Derek Rawlings ,  Brian Slingsby ,  Andrew Whittington

发明人： Andrew Eatherton ,  Gerard Giblin ,  Richard Green ,  Jennifer Doughty ,  Karamjit Jandu ,  William Mitchell ,  Alan Naylor ,  Giovanni Palombi ,  Derek Rawlings ,  Brian Slingsby ,  Andrew Whittington

IPC分类号： A61K31/53 ,  A61K31/501 ,  A61K31/506 ,  A61K31/497 ,  A61K31/4439 ,  C07D417/02 ,  C07D413/02 ,  C07D403/02 ,  C07D401/02

CPC分类号： C07D213/82 ,  C07D401/12 ,  C07D413/12

摘要： The present invention relates to novel pyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.

摘要翻译： 本发明涉及新颖的吡啶衍生物，含有这些化合物的药物组合物及其在治疗疾病尤其是疼痛中的用途，该疾病通过大麻素受体的活性的增加或减少直接或间接引起。

公开(公告)号：US20060247261A1

公开(公告)日：2006-11-02

申请号：US10524469

申请日：2003-08-19

申请人： Andrew Eatherton ,  Gerard Giblin ,  Richard Green ,  Jennifer Doughty ,  William Mitchell ,  Alan Naylor ,  Derek Rawlings ,  Brian Slingsby ,  Andrew Whittington

发明人： Andrew Eatherton ,  Gerard Giblin ,  Richard Green ,  Jennifer Doughty ,  William Mitchell ,  Alan Naylor ,  Derek Rawlings ,  Brian Slingsby ,  Andrew Whittington

IPC分类号： A61K31/506 ,  A61K31/505 ,  C07D403/02

CPC分类号： C07D239/42 ,  C07D401/12

摘要： The present invention relates to novel pyrimidine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.

摘要翻译： 本发明涉及新颖的嘧啶衍生物，含有这些化合物的药物组合物及其在治疗疾病尤其是疼痛中的用途，该疾病是由大麻素受体的活性的增加或减少直接或间接引起的。

公开(公告)号：US20070219229A1

公开(公告)日：2007-09-20

申请号：US11570099

申请日：2005-06-07

申请人： Andrew Eatherton ,  Gerard Giblin ,  Matthew Johnson ,  William Mitchell ,  Brian Slingsby ,  Alcide Perboni

发明人： Andrew Eatherton ,  Gerard Giblin ,  Matthew Johnson ,  William Mitchell ,  Brian Slingsby ,  Alcide Perboni

IPC分类号： C07D471/04 ,  A61K31/435 ,  A61P29/00

CPC分类号： C07D471/04

摘要： The present invention relates to novel pyrrolopyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.

摘要翻译： 本发明涉及新型吡咯并吡啶衍生物，含有这些化合物的药物组合物及其用于治疗由大麻素受体的活性增加或减少而直接或间接引起的疾病，特别是疼痛的疾病。

公开(公告)号：US20060293354A1

公开(公告)日：2006-12-28

申请号：US10524470

申请日：2003-08-19

申请人： Andrew Eatherton

发明人： Andrew Eatherton

IPC分类号： A61K31/506 ,  C07D405/02

CPC分类号： C07D239/42 ,  C07D401/06 ,  C07D401/12 ,  C07D403/06 ,  C07D405/12 ,  C07D409/12

摘要： The present invention relates to novel pyrimidine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.