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公开(公告)号：US20070129367A1
公开(公告)日：2007-06-07
申请号：US10528592
申请日：2003-09-25
申请人： Andrew Eatherton , Gerard Giblin , Richard Green , Jennifer Doughty , Karamjit Jandu , William Mitchell , Alan Naylor , Giovanni Palombi , Derek Rawlings , Brian Slingsby , Andrew Whittington
发明人： Andrew Eatherton , Gerard Giblin , Richard Green , Jennifer Doughty , Karamjit Jandu , William Mitchell , Alan Naylor , Giovanni Palombi , Derek Rawlings , Brian Slingsby , Andrew Whittington
IPC分类号： A61K31/53 , A61K31/501 , A61K31/506 , A61K31/497 , A61K31/4439 , C07D417/02 , C07D413/02 , C07D403/02 , C07D401/02
CPC分类号： C07D213/82 , C07D401/12 , C07D413/12
摘要： The present invention relates to novel pyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.
摘要翻译： 本发明涉及新颖的吡啶衍生物，含有这些化合物的药物组合物及其在治疗疾病尤其是疼痛中的用途，该疾病通过大麻素受体的活性的增加或减少直接或间接引起。
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公开(公告)号：US20060240048A1
公开(公告)日：2006-10-26
申请号：US10528613
申请日：2003-09-25
申请人： Andrew Eatherton , Gerard Martin Giblin , Richard Green , Jennifer Doughty , Karamjit Jandu , William Mitchell , Alan Naylor , Giovanni Palombi , Derek Rawlings , Brian Slingsby , Andrew Whittington
发明人： Andrew Eatherton , Gerard Martin Giblin , Richard Green , Jennifer Doughty , Karamjit Jandu , William Mitchell , Alan Naylor , Giovanni Palombi , Derek Rawlings , Brian Slingsby , Andrew Whittington
IPC分类号： A61K47/00
CPC分类号： C07D213/82 , C07D401/06 , C07D403/06 , C07D405/12 , C07D409/12
摘要： The present invention relates to novel pyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.
摘要翻译： 本发明涉及新颖的吡啶衍生物，含有这些化合物的药物组合物及其在治疗疾病尤其是疼痛中的用途，所述疾病通过大麻素受体的活性的增加或减少而直接或间接引起。
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公开(公告)号：US20060247261A1
公开(公告)日：2006-11-02
申请号：US10524469
申请日：2003-08-19
申请人： Andrew Eatherton , Gerard Giblin , Richard Green , Jennifer Doughty , William Mitchell , Alan Naylor , Derek Rawlings , Brian Slingsby , Andrew Whittington
发明人： Andrew Eatherton , Gerard Giblin , Richard Green , Jennifer Doughty , William Mitchell , Alan Naylor , Derek Rawlings , Brian Slingsby , Andrew Whittington
IPC分类号： A61K31/506 , A61K31/505 , C07D403/02
CPC分类号： C07D239/42 , C07D401/12
摘要： The present invention relates to novel pyrimidine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.
摘要翻译： 本发明涉及新颖的嘧啶衍生物，含有这些化合物的药物组合物及其在治疗疾病尤其是疼痛中的用途，该疾病是由大麻素受体的活性的增加或减少直接或间接引起的。
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公开(公告)号：US20070219229A1
公开(公告)日：2007-09-20
申请号：US11570099
申请日：2005-06-07
申请人： Andrew Eatherton , Gerard Giblin , Matthew Johnson , William Mitchell , Brian Slingsby , Alcide Perboni
发明人： Andrew Eatherton , Gerard Giblin , Matthew Johnson , William Mitchell , Brian Slingsby , Alcide Perboni
IPC分类号： C07D471/04 , A61K31/435 , A61P29/00
CPC分类号： C07D471/04
摘要： The present invention relates to novel pyrrolopyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.
摘要翻译： 本发明涉及新型吡咯并吡啶衍生物，含有这些化合物的药物组合物及其用于治疗由大麻素受体的活性增加或减少而直接或间接引起的疾病，特别是疼痛的疾病。
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公开(公告)号：USD826868S1
公开(公告)日：2018-08-28
申请号：US29568085
申请日：2016-06-15
申请人： William Mitchell
设计人： William Mitchell
摘要： The design consists of the features of shape, ornament, pattern and configuration of a CABLE HOLDER shown in the drawings.Drawings of the design are included.
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6.发明授权公开(公告)号：US09981918B2
公开(公告)日：2018-05-29
申请号：US14241374
申请日：2012-08-28
申请人： Leticia M. Toledo-Sherman , Celia Dominguez , Michael Prime , Peter Johnson , Ignacio Muñoz-Sanjuán , Stephen Martin Courtney , William Mitchell , Christopher John Brown , Paula C. De Aguiar Pena
发明人： Leticia M. Toledo-Sherman , Celia Dominguez , Michael Prime , Peter Johnson , Ignacio Muñoz-Sanjuán , Stephen Martin Courtney , William Mitchell , Christopher John Brown , Paula C. De Aguiar Pena
IPC分类号： C07D237/28 , A61K31/70 , C07D239/28 , C07D405/14 , C07D403/04 , C07D403/10 , C07D405/04 , C07D405/10 , C07D239/42 , C07D409/04 , C07D413/04 , C07D417/04 , C07D471/04 , C07D491/048 , C07D491/052 , C07H13/10 , C07D401/04 , C07D401/12 , C07D403/12 , C07D405/12
CPC分类号： C07D239/28 , C07D239/42 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/10 , C07D405/12 , C07D405/14 , C07D409/04 , C07D413/04 , C07D417/04 , C07D471/04 , C07D491/048 , C07D491/052 , C07H13/10
摘要： Certain chemical entities are provided herein. Also provided are pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one chemical entity as a single active agent or administering at least one chemical entity in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity.
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公开(公告)号：US09577197B2
公开(公告)日：2017-02-21
申请号：US14234235
申请日：2012-06-21
申请人： Amy Phillips , Nicolas Blouin , William Mitchell , Steven Tierney
发明人： Amy Phillips , Nicolas Blouin , William Mitchell , Steven Tierney
IPC分类号： H01L51/00 , C07D495/04 , C08G61/12 , C07D519/00 , H01L51/42
CPC分类号： H01L51/0036 , C07D495/04 , C07D519/00 , C08G61/123 , C08G61/126 , C08G2261/3245 , C08G2261/3246 , C08G2261/3247 , H01L51/0043 , H01L51/0047 , H01L51/4253 , Y02E10/549
摘要： The invention relates to novel polymers containing one or more 3,7-dialkyl-benzo[1,2-b:4,5-b′]dithiophene repeating units, methods for their preparation and monomers used therein, blends, mixtures and formulations containing them, the use of the polymers, blends, mixtures and formulations as semiconductor in organic electronic (OE) devices, especially in organic photovoltaic (OPV) devices, and to OE and OPV devices comprising these polymers, blends, mixtures or formulations.
摘要翻译： 本发明涉及含有一种或多种3,7-二烷基 - 苯并[1,2-b：4,5-b']二噻吩重复单元的新型聚合物，其制备方法及其中使用的单体，共混物，混合物和制剂，其含有 他们，在有机电子（OE）器件中，特别是有机光伏（OPV）器件中的聚合物，共混物，混合物和配方作为半导体以及包含这些聚合物，共混物，混合物或制剂的OE和OPV器件的使用。
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公开(公告)号：US09373801B2
公开(公告)日：2016-06-21
申请号：US13982004
申请日：2012-01-04
CPC分类号： H01L51/0094 , C07F7/0812 , H01L51/0072 , H01L51/0541 , H01L51/0558 , Y02E10/549
摘要： The invention relates to benzo[h]benz[5,6]acridino[2,1,9,8-klmna]acridines, methods of their preparation, their use as semiconductors in organic electronic (OE) devices, and to OE devices comprising them.
摘要翻译： 本发明涉及苯并[h]苯并[5,6]吖啶并[2,1,9,8-klmna]吖啶，其制备方法，它们作为有机电子（OE）装置中的半导体的用途，以及包含 他们。
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公开(公告)号：US09365585B2
公开(公告)日：2016-06-14
申请号：US13578931
申请日：2010-12-22
IPC分类号： C07D495/04 , C09K19/34 , C09K19/40 , H01L51/50 , H01L51/54 , C08G61/12 , C09K19/38 , H01L51/00 , C09K19/04 , H01L51/42
CPC分类号： C07D495/04 , C08G61/126 , C08G2261/124 , C08G2261/1428 , C08G2261/3243 , C08G2261/414 , C08G2261/91 , C09K19/3477 , C09K19/3491 , C09K19/3497 , C09K19/38 , C09K19/40 , C09K2019/0448 , C09K2019/0496 , H01L51/0036 , H01L51/0037 , H01L51/0043 , H01L51/4253 , Y02E10/549
摘要： The invention relates to novel polymers containing repeating units based on benzodithiophene or derivatives thereof, monomers and methods for their preparation, their use as semiconductors in organic electronic (OE) devices, especially in organic photovoltaic (OPV) devices, and to OE and OPV devices comprising these polymers.
摘要翻译： 本发明涉及包含基于苯并二噻吩或其衍生物的重复单元的新型聚合物，单体及其制备方法，它们用作有机电子（OE）器件中的半导体，特别是在有机光伏（OPV）器件中以及OE和OPV器件 包括这些聚合物。
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公开(公告)号：US20140042371A1
公开(公告)日：2014-02-13
申请号：US14112696
申请日：2012-03-23
申请人： Nicolas Blouin , William Mitchell , Amy Topley , Steven Tierney
发明人： Nicolas Blouin , William Mitchell , Amy Topley , Steven Tierney
IPC分类号： H01L51/00
CPC分类号： H01L51/0043 , B82Y10/00 , C08G61/123 , C08G61/126 , C08G2261/1428 , C08G2261/146 , C08G2261/3223 , C08G2261/3243 , C08G2261/3246 , C08G2261/334 , C08G2261/344 , C08G2261/414 , C08G2261/91 , H01L51/0036 , H01L51/0037 , H01L51/4253 , H01L2251/308 , Y02E10/549 , Y02P70/521
摘要： The invention relates to novel polymers containing one or more repeating units based on 4,8-bis(1,1-difluoralkyl)-benzo[1,2-b:4,5-b′]dithiophene or derivatives thereof, methods for their preparation and monomers used therein, blends, mixtures and formulations containing them, the use of the polymers, blends, mixtures and formulations as semiconductor in organic electronic (OE) devices, especially in organic photovoltaic (OPV) devices, and to OE and OPV devices comprising these polymers, blends, mixtures or formulations.
摘要翻译： 本发明涉及含有一个或多个基于4,8-双（1,1-二氟烷基） - 苯并[1,2-b：4,5-b']二噻吩或其衍生物的重复单元的新型聚合物，其方法为 其中使用的制剂和单体，含有它们的共混物，混合物和制剂，在有机电子（OE）装置中，特别是有机光伏（OPV）装置以及OE和OPV装置中使用聚合物，共混物，混合物和制剂作为半导体 包括这些聚合物，共混物，混合物或制剂。
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