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    RESYNCHRONIZATION METHOD AND APPARATUS BASED ON INTRINSIC ATRIAL RATE
    3.
    发明申请
    RESYNCHRONIZATION METHOD AND APPARATUS BASED ON INTRINSIC ATRIAL RATE 有权
    基于内在速率的再生方法和装置

    公开(公告)号：US20070208386A1

    公开(公告)日：2007-09-06

    申请号：US11676339

    申请日：2007-02-19

    申请人： Andrew Kramer ,  Veerichetty Kadhiresan ,  Jiang Ding ,  Lawrence Baumann ,  Scott Vanderlinde

    发明人： Andrew Kramer ,  Veerichetty Kadhiresan ,  Jiang Ding ,  Lawrence Baumann ,  Scott Vanderlinde

    IPC分类号： A61N1/05

    CPC分类号： A61N1/3627 ,  A61N1/3682

    摘要： A method and system for setting the operating parameters of a cardiac rhythm management device in which a plurality of parameter optimization algorithms are available. A measured feature of an electrophysiological signal such as QRS width has been shown to be useful in selecting among certain parameter optimization algorithms. In one embodiment, one or more resynchronization pacing parameters are set based on one or both of the feature extracted from an electrogram signal and the value of a resynchronization pacing parameter which tends to minimize the intrinsic atrial rate.

    摘要翻译： 一种用于设定多个参数优化算法可用的心律管理装置的操作参数的方法和系统。 电生理信号（如QRS宽度）的测量特征已被证明可用于某些参数优化算法中的选择。 在一个实施例中，基于从电描记信号提取的特征中的一个或两个以及倾向于使固有心房率最小化的再同步起搏参数的值来设置一个或多个再同步起搏参数。

    Safety pacing in multi-site CRM devices
    8.
    发明申请
    Safety pacing in multi-site CRM devices 有权
    多站点CRM设备中的安全起搏

    公开(公告)号：US20050004606A1

    公开(公告)日：2005-01-06

    申请号：US10839268

    申请日：2004-05-05

    申请人： Jeffrey Stahmann ,  Andrew Kramer ,  Hugh Calkins

    发明人： Jeffrey Stahmann ,  Andrew Kramer ,  Hugh Calkins

    IPC分类号： A61N1/362

    CPC分类号： A61N1/368 ,  A61N1/3622 ,  A61N1/3627 ,  A61N1/3684

    摘要： Safety pacing in multi-site cardiac rhythm management (CRM) devices is provided. According to various method embodiments, a first cardiac signal from a first cardiac region and a second cardiac signal from a second cardiac region are sensed. The first cardiac region is paced to maintain at least a minimum cardiac rate, and the second cardiac region is paced to maintain at least the minimum cardiac rate when a pace in the first cardiac region is inhibited. Other aspects and embodiments are provided herein.

    摘要翻译： 提供了多站点心律管理（CRM）设备中的安全起搏。 根据各种方法实施例，感测来自第一心脏区域的第一心脏信号和来自第二心脏区域的第二心脏信号。 第一心脏区域起搏以保持至少最小心率，并且当第一心脏区域中的步调被抑制时，第二心脏区域起搏以保持至少最小心率。 本文提供了其它方面和实施例。

    Method and apparatus for controlling cardiac therapy based on electromechanical timing
    9.
    发明申请
    Method and apparatus for controlling cardiac therapy based on electromechanical timing 有权
    基于机电定时控制心脏治疗的方法和装置

    公开(公告)号：US20060293714A1

    公开(公告)日：2006-12-28

    申请号：US11168024

    申请日：2005-06-28

    申请人： Rodney Salo ,  Joseph Pastore ,  Andrew Kramer ,  Jeffrey Stahmann ,  Jesse Hartley

    发明人： Rodney Salo ,  Joseph Pastore ,  Andrew Kramer ,  Jeffrey Stahmann ,  Jesse Hartley

    IPC分类号： A61N1/36

    CPC分类号： A61N1/3627 ,  A61M5/14276 ,  A61N1/36521 ,  A61N1/36585 ,  A61N1/3756

    摘要： Devices and methods for therapy control based on electromechanical timing involve detecting electrical activation of a patient's heart, and detecting mechanical cardiac activity resulting from the electrical activation. A timing relationship is determined between the electrical activation and the mechanical activity. A therapy is controlled based on the timing relationship. The therapy may improve intraventricular dyssynchrony of the patient's heart, or treat at least one of diastolic and systolic dysfunction and/or dyssynchrony of the patient's heart, for example. Electrical activation may be detected by sensing delivery of an electrical stimulation pulse to the heart or sensing intrinsic depolarization of the patient's heart. Mechanical activity may be detected by sensing heart sounds, a change in one or more of left ventricular impedance, ventricular pressure, right ventricular pressure, left atrial pressure, right atrial pressure, systemic arterial pressure and pulmonary artery pressure.

    摘要翻译： 基于机电定时的治疗控制的装置和方法涉及检测患者心脏的电激活，以及检测由电激活引起的机械心脏活动。 在电激活和机械活动之间确定时序关系。 基于时间关系控制治疗。 该治疗可以改善患者心脏的心室内不同步，或治疗患者心脏的舒张期和收缩功能障碍和/或不同步中的至少一种。 可以通过感测向心脏传递电刺激脉冲或感测患者心脏的固有去极化来检测电激活。 可以通过感测心脏声音，左心室阻抗，心室压力，右心室压力，左心房压力，右心房压力，全身动脉压力和肺动脉压力中的一个或多个的变化来检测机械活动。

    REDUCTION OF INTERACTION WITH TACHYARRHYTHMIA DETECTION BY NEGATIVE OFFSET PACING
    10.
    发明申请
    REDUCTION OF INTERACTION WITH TACHYARRHYTHMIA DETECTION BY NEGATIVE OFFSET PACING 有权
    减少与负面偏差相关的TACHYARRHYTHMIA检测

    公开(公告)号：US20060116728A1

    公开(公告)日：2006-06-01

    申请号：US11276031

    申请日：2006-02-10

    申请人： Jeffrey Stahmann ,  Andrew Kramer ,  Julio Spinelli

    发明人： Jeffrey Stahmann ,  Andrew Kramer ,  Julio Spinelli

    IPC分类号： A61N1/36

    CPC分类号： A61N1/3622

    摘要： A device and method is disclosed for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified negative offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. Techniques are presented for preventing tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.

    摘要翻译： 公开了一种用于改善心律失常检测的装置和方法，当通过将指定的负偏移间隔分开的两个心室递送步调来再同步时，心律失常检测。 逃避间隔和快速性心律失常检测的时间是基于指定为速率心室的心室之一的感觉。 提出技术用于在速率心室在另一脑室之后起搏时预防快速性心律失常检测受到损害。