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    Metabolite of xanthine Phosphodiesterase 5 inhibitor and derivatives thereof useful for treatment of erectile dysfunction
    2.
    发明授权
    Metabolite of xanthine Phosphodiesterase 5 inhibitor and derivatives thereof useful for treatment of erectile dysfunction 失效
    黄嘌呤的代谢物磷酸二酯酶5抑制剂及其衍生物可用于治疗勃起功能障碍

    公开(公告)号：US07312223B2

    公开(公告)日：2007-12-25

    申请号：US10901574

    申请日：2004-07-29

    申请人： Anima Ghosal ,  Wei Tong ,  Swapan K. Chowdhury ,  Shmuel Zbaida ,  Mark A. Wirth ,  Kevin B. Alton ,  James E. Patrick ,  Craig D. Boyle ,  Andrew Stamford

    发明人： Anima Ghosal ,  Wei Tong ,  Swapan K. Chowdhury ,  Shmuel Zbaida ,  Mark A. Wirth ,  Kevin B. Alton ,  James E. Patrick ,  Craig D. Boyle ,  Andrew Stamford

    IPC分类号： C07D473/06 ,  A61K31/522 ,  A61P9/10 ,  A61P9/12

    CPC分类号： C07D473/06

    摘要： The present invention is directed to a metabolite of a xanthine Phosphodiesterase type 5 inhibitor having the following structure derivatives, and formulations thereof, and processes for preparing the same. Further disclosed are methods of treating a physiological disorder, symptom or disease in a patient, comprising administering to the patient an effective amount of the above compound, wherein the physiological disorder, symptom or disease is a urogenital, cardiovascular, cerebrovascular or peripheral vascular disorder, angina pectoris, hypertension, restenosis post angioplasty, endarterectomy, stent introduction, cerebral stroke, a respiratory tract disorder such as an allergic condition associated with atopy, pulmonary hypertension, an ischemic heart disorder, impaired glucose tolerance, diabetes and its related complication, insulin resistance syndrome, hyperglycemia, polycystic ovarian syndrome, a glomerular disorder, renal insufficiency, nephritis, a tubular interstitial disorder, an autoimmune disorder, glaucoma, intestinal motility, cachexia or cancer.

    摘要翻译： 本发明涉及具有以下结构衍生物的黄嘌呤磷酸二酯酶5型抑制剂的代谢物及其制剂及其制备方法。 进一步公开的是治疗患者的生理障碍，症状或疾病的方法，包括向患者施用有效量的上述化合物，其中所述生理障碍，症状或疾病是泌尿生殖系统，心血管，脑血管或外周血管疾病， 心绞痛，高血压，血管成形术后再狭窄，内膜切除术，支架引入，脑中风，呼吸道疾病如与过敏相关的过敏性疾病，肺动脉高压，缺血性心脏病，糖耐量异常，糖尿病及其相关并发症，胰岛素抵抗 综合征，高血糖症，多囊卵巢综合征，肾小球疾病，肾功能不全，肾炎，管状间质性疾病，自身免疫性疾病，青光眼，肠蠕动，恶病质或癌症。

    BODY TRANSPORT APPARATUS WITH INTEGRATED HANDLES
    4.
    发明申请
    BODY TRANSPORT APPARATUS WITH INTEGRATED HANDLES 有权
    身体运输装置与整体手柄

    公开(公告)号：US20140082836A1

    公开(公告)日：2014-03-27

    申请号：US14090952

    申请日：2013-11-26

    申请人： James E. Patrick ,  Geoffrey David Pile

    发明人： James E. Patrick ,  Geoffrey David Pile

    IPC分类号： A47C27/08 ,  A61G7/10

    CPC分类号： A47C27/081 ,  A47C31/08 ,  A61G1/02 ,  A61G7/05769 ,  A61G7/05784 ,  A61G7/1026 ,  A61G7/1028 ,  A61G10/005

    摘要： A body transport apparatus may include top and bottom portions that have a perimeter seal and an interior seal offset from the perimeter seal to define a non-inflatable frame portion and an inflatable air mattress portion. The bottom portion includes a plurality of air exit holes configured to provide an air cushion under the mattress portion when the mattress portion is inflated. The frame portion includes a plurality of handle openings and a channel so that the inflatable air mattress portion extends through the frame portion for a remote receptacle disposed outside the perimeter seal. A partial body transport apparatus may include the channel extending into the frame portion so that a remote receptacle is disposed within the perimeter seal and an inflatable air mattress portion having a longitudinal extent that is approximately 75% to 125% of a lateral extent.

    摘要翻译： 身体运输装置可以包括具有周界密封件的顶部和底部部分以及从周边密封件偏置以限定不可充气的框架部分和可充气的空气床垫部分的内部密封件。 底部包括多个空气出口孔，其构造成当床垫部分被充气时在床垫部分下方提供气垫。 框架部分包括多个手柄开口和通道，使得可膨胀空气床垫部分延伸穿过框架部分，用于设置在周边密封件外部的远程容器。 部分体输送装置可以包括延伸到框架部分中的通道，使得远程容器设置在周边密封件内，并且可膨胀空气床垫部分具有大约横向范围的大约75％至125％的纵向范围。

    PATIENT TRANSFER KIT
    5.
    发明申请
    PATIENT TRANSFER KIT 有权
    病人转运工具包

    公开(公告)号：US20130000050A1

    公开(公告)日：2013-01-03

    申请号：US13607271

    申请日：2012-09-07

    申请人： James E. Patrick

    发明人： James E. Patrick

    IPC分类号： A47C27/08

    CPC分类号： A61G7/1028 ,  A61G7/002 ,  A61G7/1021 ,  A61G7/1046

    摘要： A patient transfer kit including an inflatable mattress, alternatively with a rigid top board with a patient restraint system on which a patient can be placed, when patient immobilization is required. A portable cart is included with a chamber for storage of a plurality of mattresses. The cart also has a gas/air blower and power supply system for powering the blower. The power system includes provision for drawing power from line AC/DC, and has a rechargeable battery and charger for maintaining the battery by connecting the supply to the line AC/DC. The mattress has a perforated bottom surface for exit of air to provide an air cushion, and is constructed with a white top surface and a dark bottom surface for optimum recognition of contamination, and identification of the bottom surface which must be placed downward. The cart is coated with an antimicrobial substance to minimize the risk of contaminants.

    摘要翻译： 一种患者转移套件，其包括充气床垫，或者当需要患者固定时，具有带有患者约束系统的刚性顶板，患者可以放置在其上。 便携式推车包括有用于存储多个床垫的室。 推车还具有用于为鼓风机供电的气/气鼓风机和电源系统。 电力系统包括用于从AC / DC线获取电力的功能，并且具有用于通过将电源连接到AC / DC线来维持电池的可充电电池和充电器。 床垫具有穿孔的底面，用于排出空气以提供气垫，并且构造有白色顶部表面和黑色底部表面，以最佳地识别污染物，以及识别必须向下放置的底部表面。 手推车涂有抗菌物质，以尽量减少污染物的风险。

    Body transport apparatus with integrated handles
    7.
    发明授权
    Body transport apparatus with integrated handles 有权
    车身运输装置带有整体手柄

    公开(公告)号：US09241580B2

    公开(公告)日：2016-01-26

    申请号：US14090952

    申请日：2013-11-26

    申请人： James E. Patrick ,  Geoffrey David Pile

    发明人： James E. Patrick ,  Geoffrey David Pile

    IPC分类号： A61G7/14 ,  A47C31/08 ,  A47C27/08 ,  A61G7/10 ,  A61G1/02 ,  A61G7/057 ,  A61G10/00

    CPC分类号： A47C27/081 ,  A47C31/08 ,  A61G1/02 ,  A61G7/05769 ,  A61G7/05784 ,  A61G7/1026 ,  A61G7/1028 ,  A61G10/005

    摘要： A body transport apparatus may include top and bottom portions that have a perimeter seal and an interior seal offset from the perimeter seal to define a non-inflatable frame portion and an inflatable air mattress portion. The bottom portion includes a plurality of air exit holes configured to provide an air cushion under the mattress portion when the mattress portion is inflated. The frame portion includes a plurality of handle openings and a channel so that the inflatable air mattress portion extends through the frame portion for a remote receptacle disposed outside the perimeter seal. A partial body transport apparatus may include the channel extending into the frame portion so that a remote receptacle is disposed within the perimeter seal and an inflatable air mattress portion having a longitudinal extent that is approximately 75% to 125% of a lateral extent.

    摘要翻译： 身体运输装置可以包括具有周界密封件的顶部和底部部分以及从周边密封件偏置以限定不可充气的框架部分和可充气的空气床垫部分的内部密封件。 底部包括多个空气出口孔，其构造成当床垫部分被充气时在床垫部分下方提供气垫。 框架部分包括多个手柄开口和通道，使得可膨胀空气床垫部分延伸穿过框架部分，用于设置在周边密封件外部的远程容器。 部分体输送装置可以包括延伸到框架部分中的通道，使得远程容器设置在周边密封件内，并且可膨胀空气床垫部分具有大约横向范围的大约75％至125％的纵向范围。

    Body transport apparatus
    8.
    发明授权
    Body transport apparatus 有权
    身体运输器具

    公开(公告)号：US09125777B2

    公开(公告)日：2015-09-08

    申请号：US13302703

    申请日：2011-11-22

    申请人： James E. Patrick

    发明人： James E. Patrick

    IPC分类号： A61G7/14 ,  A61G1/02 ,  A61G7/10 ,  A61G7/00 ,  A61G7/02 ,  A61G7/057 ,  A61G7/002 ,  A61G10/00 ,  A61G13/10

    CPC分类号： A61G7/1021 ,  A61G1/02 ,  A61G7/0005 ,  A61G7/002 ,  A61G7/02 ,  A61G7/05769 ,  A61G7/05784 ,  A61G7/1026 ,  A61G7/1028 ,  A61G7/103 ,  A61G7/1034 ,  A61G7/1046 ,  A61G10/005 ,  A61G13/102 ,  A61G2200/32

    摘要： A body transport apparatus including an inflatable air mattress with a plurality of air exit holes on the bottom to provide an air cushion when the mattress is inflated and a cover portion connected to the mattress adjacent a perimeter to define an enclosed volume. The cover portion may include a selectively closeable passageway. A flap may be defined in the cover portion that is movable between open and closed configurations. A plurality of hollows may be defined in the cover portion when inflated to define a body contact area that is less than a surface area of the top surface.

    摘要翻译： 一种身体输送装置，包括：充气式气垫，其底部具有多个空气出口孔，以在床垫充气时提供气垫，以及与邻近周边的床垫连接以限定封闭容积的盖部。 盖部分可以包括选择性地关闭的通道。 可以在盖部分中限定可在打开和关闭构造之间移动的翼片。 当充气时可以在盖部分中限定多个中空部，以限定小于上表面的表面积的身体接触面积。