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![3,6-Disubstituted azabicyclo [3.1.0] hexane derivatives as muscarinic receptor antagonists](/abs-image/US/2006/09/28/US20060217432A1/abs.jpg.150x150.jpg)
1.发明申请3,6-Disubstituted azabicyclo [3.1.0] hexane derivatives as muscarinic receptor antagonists 失效3,6-二取代的氮杂双环[3.1.0]己烷衍生物作为毒蕈碱受体拮抗剂公开(公告)号：US20060217432A1
公开(公告)日：2006-09-28
申请号：US10537851
申请日：2002-12-10
申请人： Anita Mehta , Arundutt Silamkoti , Bruhaspathy Miriyala , Sudershan Arora , Boju Srinivasulu , Bireshwar Mukherjee , Jang Gupta
发明人： Anita Mehta , Arundutt Silamkoti , Bruhaspathy Miriyala , Sudershan Arora , Boju Srinivasulu , Bireshwar Mukherjee , Jang Gupta
IPC分类号： A61K31/403 , C07D209/02
CPC分类号： C07D401/06 , C07D209/52 , C07D405/06 , C07D405/12 , C07D405/14 , C07D409/14
摘要： The invention relates to derivatives of 3,6-disubstituted azabicyclo[3.1.0]hexanes of structure (I). The compounds of this invention can function as muscarinic receptor antagonists, and can be used for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to pharmaceutical compositions containing the compounds of the present invention and the methods for treating the diseases mediated through muscarinic receptors.
摘要翻译： 本发明涉及结构（I）的3,6-二取代的氮杂双环[3.1.0]己烷的衍生物。 本发明化合物可用作毒蕈碱受体拮抗剂，可用于治疗通过毒蕈碱受体介导的呼吸道，尿路和胃肠道系统的各种疾病。 本发明还涉及含有本发明化合物的药物组合物和通过毒蕈碱受体介导的疾病的治疗方法。
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2.发明授权3,6-Disubstituted azabicyclo derivatives as muscarinic receptor antagonists 失效3,6-二取代的氮杂双环衍生物作为毒蕈碱受体拮抗剂公开(公告)号：US07232835B2
公开(公告)日：2007-06-19
申请号：US10537851
申请日：2002-12-10
申请人： Anita Mehta , Arundutt Viswanatham Silamkoti , Bruhaspathy Miriyala , Sudershan Kumar Arora , Boju Srinivasulu , Bireshwar Mukherjee , Jang Bahadur Gupta
发明人： Anita Mehta , Arundutt Viswanatham Silamkoti , Bruhaspathy Miriyala , Sudershan Kumar Arora , Boju Srinivasulu , Bireshwar Mukherjee , Jang Bahadur Gupta
IPC分类号： A01N43/40 , A01N43/00 , A61K31/445 , A61K31/55 , C07D221/02
CPC分类号： C07D401/06 , C07D209/52 , C07D405/06 , C07D405/12 , C07D405/14 , C07D409/14
摘要： This invention relates to derivatives of 3,6-disubstituted azabicyclo compounds. The compounds of this invention can function as muscarinic receptor antagonists, and can be used for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to pharmaceutical compositions containing the compounds of the present invention and the methods for treating the diseases mediated through muscarinic receptors.
摘要翻译： 本发明涉及3,6-二取代的氮杂二环化合物的衍生物。 本发明化合物可用作毒蕈碱受体拮抗剂，可用于治疗通过毒蕈碱受体介导的呼吸道，尿路和胃肠道系统的各种疾病。 本发明还涉及含有本发明化合物的药物组合物和通过毒蕈碱受体介导的疾病的治疗方法。
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