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公开(公告)号:US20100172866A1
公开(公告)日:2010-07-08
申请号:US12598802
申请日:2008-05-05
申请人: Ann Kwong , Nagraj Mani , Yi Zhou , Chao Lin
发明人: Ann Kwong , Nagraj Mani , Yi Zhou , Chao Lin
IPC分类号: A61K38/21 , A61K31/497 , A61K31/7068 , A61P31/12
CPC分类号: A61K31/497 , A61K31/7068 , A61K45/06 , A61K2300/00
摘要: The present invention relates to therapeutic combinations comprising a protease inhibitor and a polymerase inhibitor for the treatment of HCV. The present invention also relates to therapeutic combinations comprising VX-950 and a polymerase inhibitor. Also within the scope of the invention are methods using the therapeutic combinations of the present invention for treating HCV infection or alleviating one or more symptoms thereof in a patient. The present invention also provides kits comprising the combinations of the present invention.
摘要翻译: 本发明涉及包含用于治疗HCV的蛋白酶抑制剂和聚合酶抑制剂的治疗组合。 本发明还涉及包含VX-950和聚合酶抑制剂的治疗组合。 也在本发明的范围内的方法是使用本发明的治疗组合治疗HCV感染或减轻患者中的一种或多种症状的方法。 本发明还提供包含本发明组合的试剂盒。
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公开(公告)号:US20120295843A1
公开(公告)日:2012-11-22
申请号:US13564286
申请日:2012-08-01
申请人: Ann Kwong , Nagraj Mani , Yi Zhou , Chao Lin
发明人: Ann Kwong , Nagraj Mani , Yi Zhou , Chao Lin
CPC分类号: A61K31/497 , A61K31/7068 , A61K45/06 , A61K2300/00
摘要: The present invention relates to therapeutic combinations comprising a protease inhibitor and a polymerase inhibitor for the treatment of HCV. The present invention also relates to therapeutic combinations comprising VX-950 and a polymerase inhibitor. Also within the scope of the invention are methods using the therapeutic combinations of the present invention for treating HCV infection or alleviating one or more symptoms thereof in a patient. The present invention also provides kits comprising the combinations of the present invention.
摘要翻译: 本发明涉及包含用于治疗HCV的蛋白酶抑制剂和聚合酶抑制剂的治疗组合。 本发明还涉及包含VX-950和聚合酶抑制剂的治疗组合。 也在本发明的范围内的方法是使用本发明的治疗组合治疗HCV感染或减轻患者中的一种或多种症状的方法。 本发明还提供包含本发明组合的试剂盒。
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公开(公告)号:US08258116B2
公开(公告)日:2012-09-04
申请号:US12598802
申请日:2008-05-05
申请人: Ann Kwong , Nagraj Mani , Yi Zhou , Chao Lin
发明人: Ann Kwong , Nagraj Mani , Yi Zhou , Chao Lin
CPC分类号: A61K31/497 , A61K31/7068 , A61K45/06 , A61K2300/00
摘要: The present invention relates to therapeutic combinations comprising a protease inhibitor and a polymerase inhibitor for the treatment of HCV. The present invention also relates to therapeutic combinations comprising VX-950 and a polymerase inhibitor. Also within the scope of the invention are methods using the therapeutic combinations of the present invention for treating HCV infection or alleviating one or more symptoms thereof in a patient. The present invention also provides kits comprising the combinations of the present invention.
摘要翻译: 本发明涉及包含用于治疗HCV的蛋白酶抑制剂和聚合酶抑制剂的治疗组合。 本发明还涉及包含VX-950和聚合酶抑制剂的治疗组合。 也在本发明的范围内的方法是使用本发明的治疗组合治疗HCV感染或减轻患者中的一种或多种症状的方法。 本发明还提供包含本发明组合的试剂盒。
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公开(公告)号:US5888721A
公开(公告)日:1999-03-30
申请号:US674831
申请日:1996-07-03
申请人: David Rothstein , Nagraj Mani , Zhi-Dong Jiang
发明人: David Rothstein , Nagraj Mani , Zhi-Dong Jiang
IPC分类号: C07C69/92 , C12Q1/18 , C12Q1/04 , A61K31/425 , C07C229/00 , C12Q1/02
摘要: The invention features two novel antibiotics, termed 15352A and 15352B, having the structures shown in the figures.
摘要翻译: 本发明的特征在于具有图中所示结构的两种新型抗生素,称为15352A和15352B。
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