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公开(公告)号:US20070282101A1
公开(公告)日:2007-12-06
申请号:US11731950
申请日:2007-04-02
申请人: Anna Ericsson , Andrew Burchat , Kristine Frank , David Calderwood , Lily Abbott , Maria Argiriadi , David Borhani , Kevin Cusack , Richard Dixon , Thomas Gordon , Kelly Mullen , Robert Talanian , Xiaoyun Wu , Xiaolei Zhang , Lu Wang , Biqin Li , Claude Barberis , Neil Wishart
发明人: Anna Ericsson , Andrew Burchat , Kristine Frank , David Calderwood , Lily Abbott , Maria Argiriadi , David Borhani , Kevin Cusack , Richard Dixon , Thomas Gordon , Kelly Mullen , Robert Talanian , Xiaoyun Wu , Xiaolei Zhang , Lu Wang , Biqin Li , Claude Barberis , Neil Wishart
IPC分类号: C07D409/14 , C07D409/04 , C07D413/14
CPC分类号: C07D487/04 , C07D403/12 , C07D403/14 , C07D409/04 , C07D409/14
摘要: Novel compounds of Formula (I) or pharmaceutically acceptable salts, prodrugs and biologically active metabolites thereof of Formula (I) wherein the substituents are as defined herein, which are useful as therapeutic agents.
摘要翻译: 式(I)的新型化合物或其药学上可接受的盐,前体药物和式(I)的生物活性代谢物,其中取代基如本文所定义,其可用作治疗剂。
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公开(公告)号:US20070155776A1
公开(公告)日:2007-07-05
申请号:US11675183
申请日:2007-02-15
申请人: Patrick Betschmann , Andrew Burchat , David Calderwood , Michael Curtin , Steven Davidsen , Heather Davis , Robin Frey , Howard Heyman , Gavin Hirst , Peter Hrnciar , Michael Michaelides , Melanie Muckey , Kelly Mullen , Paul Rafferty , Carol Wada
发明人: Patrick Betschmann , Andrew Burchat , David Calderwood , Michael Curtin , Steven Davidsen , Heather Davis , Robin Frey , Howard Heyman , Gavin Hirst , Peter Hrnciar , Michael Michaelides , Melanie Muckey , Kelly Mullen , Paul Rafferty , Carol Wada
IPC分类号: A61K31/4745 , A61K31/4743 , A61K31/4741 , C07D491/02 , C07D498/02
CPC分类号: A61K31/4743 , A61K31/4741 , A61K31/4745 , C07D491/04 , C07D495/04 , Y02A50/401
摘要: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
摘要翻译: 具有该式的化合物可用于抑制蛋白酪氨酸激酶。 本发明还公开了制备化合物的方法,含有该化合物的组合物和使用该化合物的处理方法。
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