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公开(公告)号:US20100166772A1
公开(公告)日:2010-07-01
申请号:US12601933
申请日:2008-05-29
申请人: Annaliesa S. Anderson , Desmond J. Clark , Zhiqiang An , Fubao Wang , Susan L. Secore , Eberhard Durr , Leslie D. Cope , Tessie McNeely
发明人: Annaliesa S. Anderson , Desmond J. Clark , Zhiqiang An , Fubao Wang , Susan L. Secore , Eberhard Durr , Leslie D. Cope , Tessie McNeely
CPC分类号: C07K16/1271 , A61K2039/505 , C07K14/4703 , C07K2317/21 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/77 , C07K2317/92
摘要: The present invention features antigen binding proteins that bind to a region found to have an epitope that can be targeted to provide protection against S. aureus infection. The region is designated herein as the “CS-D7” target region. The CS-D7 target region provides an S. aureus ORF0657n epitope that can be targeted to reduce the likelihood or severity of an S. aureus infection.
摘要翻译: 本发明的特征在于抗原结合蛋白,其结合发现具有可靶向以提供金黄色葡萄球菌感染保护的表位的区域。 该区域在此被称为“CS-D7”目标区域。 CS-D7靶区域提供金黄色葡萄球菌ORF0657n表位,其可以靶向以降低金黄色葡萄球菌感染的可能性或严重性。