-
1.发明申请公开(公告)号：US20060205759A1
公开(公告)日：2006-09-14
申请号：US11355452
申请日：2006-02-16
申请人： Annmarie Sabb , Robert Vogel , Gary Stack , Deborah Evrard , Amedeo Failli , Lalitha Krishnan , Anita Chan , Jianxin Ren , Charles Guinosso , Reinhardt Baudy , Jean Sze , Yanfang Li , Charles Stanton , Antonia Nikitenko
发明人： Annmarie Sabb , Robert Vogel , Gary Stack , Deborah Evrard , Amedeo Failli , Lalitha Krishnan , Anita Chan , Jianxin Ren , Charles Guinosso , Reinhardt Baudy , Jean Sze , Yanfang Li , Charles Stanton , Antonia Nikitenko
IPC分类号： A61K31/4745 , C07D491/02
CPC分类号： C07D209/88 , C07D233/76 , C07D491/04 , C07D493/04
摘要： The present invention provides cycloalkylfused indole, benzothiophene, benzofuran, and indene derivatives, and methods for using them to, for example, treat, prevent and/or ameliorate central nervous system diseases by antagonizing 5-HT1A receptors and modulating serotonin levels.
摘要翻译： 本发明提供环烷基稠合的吲哚，苯并噻吩，苯并呋喃和茚衍生物，以及使用它们例如通过拮抗5-HT 1A受体来治疗，预防和/或改善中枢神经系统疾病的方法。 并调节5-羟色胺水平。
-
2.发明申请公开(公告)号：US20080081910A1
公开(公告)日：2008-04-03
申请号：US11870660
申请日：2007-10-11
申请人： Annmarie Sabb , Robert Vogel , Gary Stack , Deborah Evrard , Amedeo Failli , Lalitha Krishnan , Anita Chan , Jianxin Ren , Charles Guinosso , Reinhardt Baudy , Jean Sze , Yanfang Li , Charles Stanton , Antonia Nikitenko
发明人： Annmarie Sabb , Robert Vogel , Gary Stack , Deborah Evrard , Amedeo Failli , Lalitha Krishnan , Anita Chan , Jianxin Ren , Charles Guinosso , Reinhardt Baudy , Jean Sze , Yanfang Li , Charles Stanton , Antonia Nikitenko
IPC分类号： C07D491/02 , C07D209/82 , C07D333/50
CPC分类号： C07D209/88 , C07D233/76 , C07D491/04 , C07D493/04
摘要： The present invention provides cycloalkylfused indole, benzothiophene, benzofuran, and indene derivatives, and methods for using them to, for example, treat, prevent and/or ameliorate central nervous system diseases by antagonizing 5-HT1A receptors and modulating serotonin levels.
摘要翻译： 本发明提供环烷基稠合的吲哚，苯并噻吩，苯并呋喃和茚衍生物，以及使用它们例如通过拮抗5-HT 1A受体来治疗，预防和/或改善中枢神经系统疾病的方法。 并调节5-羟色胺水平。
-
公开(公告)号：US20080009634A1
公开(公告)日：2008-01-10
申请号：US11820575
申请日：2007-06-18
申请人： Michael Winkley , Anita Chan , Ivo Jirkovsky , Kenneth Kremer , Joseph Zeldis , Antonia Nikitenko , Henry Strong , Tarek Mansour , Gulnaz Khafizova , Aranapakam Venkatesan
发明人： Michael Winkley , Anita Chan , Ivo Jirkovsky , Kenneth Kremer , Joseph Zeldis , Antonia Nikitenko , Henry Strong , Tarek Mansour , Gulnaz Khafizova , Aranapakam Venkatesan
IPC分类号： C07D277/60 , C07D487/04
CPC分类号： C07D498/04 , C07D487/04
摘要： There is provided a process for the preparation of bicyclicheteroaryl carboxaldehydes having the structural Formula I where X and Y are defined in the specification The bicyclic heteroaryl carboxaldehydes are useful as intermediates in the preparation of β-lactamase inhibitors.
摘要翻译： 提供了一种制备具有结构式I的双环杂芳基羧醛的方法，其中X和Y在说明书中定义。双环杂芳基羧醛可用作制备β-内酰胺酶抑制剂的中间体。
-
公开(公告)号：US20050209245A1
公开(公告)日：2005-09-22
申请号：US11082510
申请日：2005-03-17
申请人： Anita Chan , Jianxin Ren , Archana Sharma
发明人： Anita Chan , Jianxin Ren , Archana Sharma
IPC分类号： C07D405/12 , A61K31/496 , C07D43/02
CPC分类号： C07D405/12
摘要： Processes for preparing N-aryl-piperazine derivatives of formula I particularly (R)-4-cyano-N-[2-[4-(2,3-dihydro-1,4-benzodioxan-5-yl)-1-piperazinyl-propyl]-N-(2-pyridinyl)-benzamide, are disclosed. Compositions comprising N-aryl-piperazine derivatives and low levels of common impurities are also disclosed. In addition, products produced by the process are disclosed.
摘要翻译： 制备式I的N-芳基 - 哌嗪衍生物的方法，特别是（R）-4-氰基-N- [2- [4-（2,3-二氢-1,4-苯并二恶烷-5-基）-1-哌嗪基 丙基] -N-（2-吡啶基） - 苯甲酰胺。 还公开了包含N-芳基 - 哌嗪衍生物和低水平常见杂质的组合物。 此外，公开了通过该方法生产的产品。
-
![Process for the Synthesis of Derivatives of 2,3-Dihydro-1,4-Dioxino-[2,3-f] Quinolines](/abs-image/US/2007/05/31/US20070123705A1/abs.jpg.150x150.jpg)
5.发明申请Process for the Synthesis of Derivatives of 2,3-Dihydro-1,4-Dioxino-[2,3-f] Quinolines 失效2,3-二氢-1,4-二氧代 - [2,3-f]喹啉衍生物的合成方法公开(公告)号：US20070123705A1
公开(公告)日：2007-05-31
申请号：US11566528
申请日：2006-12-04
申请人： Anita Chan , Timothy Curran , Silvio Iera , Warren Chew , John Sellstedt , Galina Vid , Gregg Feigelson , Zhixian Ding
发明人： Anita Chan , Timothy Curran , Silvio Iera , Warren Chew , John Sellstedt , Galina Vid , Gregg Feigelson , Zhixian Ding
IPC分类号： C07D237/26 , C07D215/16
CPC分类号： C07D491/04
摘要： Methods of preparing compounds of Formula I are provided.
摘要翻译： 提供制备式I化合物的方法。
-
公开(公告)号：US20070027142A1
公开(公告)日：2007-02-01
申请号：US11491590
申请日：2006-07-24
申请人： Sreenivasulu Megati , Anita Chan , Gregg Feigelson
发明人： Sreenivasulu Megati , Anita Chan , Gregg Feigelson
IPC分类号： A61K31/551 , A61K31/498 , C07D487/04
CPC分类号： C07D221/16 , C07D471/06
摘要： The present invention relates to methods for synthesizing compounds useful as 5HT2C agonists or partial agonists, derivatives thereof, and to intermediates thereto.
摘要翻译： 本发明涉及合成可用作5HT 2C激动剂或部分激动剂，其衍生物及其中间体的化合物的方法。
-
![Process for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino-[2,3-f] quinoline](/abs-image/US/2006/04/06/US20060074240A1/abs.jpg.150x150.jpg)
7.发明申请Process for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino-[2,3-f] quinoline 失效合成2,3-二氢-1,4-二氧杂 - [2,3-f]喹啉衍生物的方法公开(公告)号：US20060074240A1
公开(公告)日：2006-04-06
申请号：US11282202
申请日：2005-11-18
申请人： Anita Chan , Timothy Curran , Silvio Iera , Warren Chew , John Sellstedt , Galina Vid , Gregg Feigelson , Zhixian Ding
发明人： Anita Chan , Timothy Curran , Silvio Iera , Warren Chew , John Sellstedt , Galina Vid , Gregg Feigelson , Zhixian Ding
IPC分类号： C07D491/00
CPC分类号： C07D491/04
摘要： Methods of preparing compounds of Formula I are provided.
摘要翻译： 提供制备式I化合物的方法。
-
8.发明申请Dispersible cationic polygalactomannan polymers for use in personal care and household care applications 有权用于个人护理和家庭护理应用的可分散阳离子聚半乳甘露聚糖公开(公告)号：US20080112907A1
公开(公告)日：2008-05-15
申请号：US11982591
申请日：2007-11-02
CPC分类号： A61Q5/02 , A61K8/0241 , A61K8/737 , A61K2800/48 , A61K2800/5426 , A61Q5/12 , A61Q19/10 , C08B37/0096 , C11D3/227
摘要： The present invention relates to polygalactomannan compositions, and more particularly cationic guar gum compositions, which, when crosslinked with glyoxal, from discrete guar particles which are capable of being easily dispersed in water which permits subsequent processing of the guar, such as washing. The guar and its derivatives are desirable for use in applications such as personal care, household care products and the like.
摘要翻译： 本发明涉及聚半乳甘露聚糖组合物，更特别是阳离子瓜尔胶组合物，当乙二醛与乙二醛交联时，该分离的瓜尔胶颗粒能够容易地分散在水中，这允许随后处理瓜尔胶，例如洗涤。 瓜尔胶及其衍生物可用于个人护理，家庭护理产品等应用中。
-
9.发明申请Preparation of N1-(2'-pyridyl)-1,2-propanediamine sulfamic acid and its use in the synthesis of biologically active piperazines 失效N1-（2'-吡啶基）-1,2-丙二胺氨基磺酸的制备及其在生物活性哌嗪合成中的应用公开(公告)号：US20050070709A1
公开(公告)日：2005-03-31
申请号：US10919099
申请日：2004-08-16
申请人： Anita Chan , Gregg Feigelson , Joseph Zeldis , Ivo Jirkovsky
发明人： Anita Chan , Gregg Feigelson , Joseph Zeldis , Ivo Jirkovsky
IPC分类号： A61P25/00 , C07D213/74 , C07D213/75 , C07D213/76 , C07D405/12 , C07D319/14 , C07D413/02
CPC分类号： C07D213/74 , C07D213/75 , C07D213/76 , C07D405/12
摘要： A process for making an N1-(2′-pyridyl)-1,2-alkanediamine sulfamic acid of formula II by reacting a compound of formula I with NH2R′ wherein R and R′ are as defined in the specification. The invention also includes the compound of formula II, and optical isomers thereof. The compound of formula II is an intermediate useful for making chiral piperazine derivatives which are active at the 5-HT1A receptor.
摘要翻译： 通过使式I化合物与NH 2 R'反应制备式II的N1-（2'-吡啶基）-1,2-链烷二胺氨基磺酸的方法，其中R和R'如说明书中所定义。 本发明还包括式II化合物及其旋光异构体。 式II化合物是可用于制备在5-HT 1A受体上有活性的手性哌嗪衍生物的中间体。
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.041 秒)
