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公开(公告)号:US08227188B2
公开(公告)日:2012-07-24
申请号:US12875695
申请日:2010-09-03
IPC分类号: C12Q1/68
CPC分类号: C12N15/1131 , C12N2310/14 , C12N2310/331 , C12N2760/16111
摘要: The invention relates to compositions and methods for modulating the expression of influenza viral genes, and more particularly to the downregulation of influenza viral genes by chemically modified oligonucleotides.
摘要翻译: 本发明涉及调节流感病毒基因表达的组合物和方法,更具体地涉及通过化学修饰的寡核苷酸下调流感病毒基因。
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公开(公告)号:US20110033859A1
公开(公告)日:2011-02-10
申请号:US12875695
申请日:2010-09-03
IPC分类号: C12Q1/68
CPC分类号: C12N15/1131 , C12N2310/14 , C12N2310/331 , C12N2760/16111
摘要: The invention relates to compositions and methods for modulating the expression of influenza viral genes, and more particularly to the downregulation of influenza viral genes by chemically modified oligonucleotides.
摘要翻译: 本发明涉及调节流感病毒基因表达的组合物和方法,更具体地涉及通过化学修饰的寡核苷酸下调流感病毒基因。
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公开(公告)号:US08912316B2
公开(公告)日:2014-12-16
申请号:US13612521
申请日:2012-09-12
申请人: Antonin De Fougerolles , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Sina Bavari , Kelly Lyn Warfield
发明人: Antonin De Fougerolles , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Sina Bavari , Kelly Lyn Warfield
IPC分类号: C12Q1/68 , C12N15/113
CPC分类号: C12N15/1137 , C12N15/1138 , C12N2310/113 , C12N2310/14 , C12N2310/17 , C12N2310/315 , C12N2310/321 , C12N2310/3515 , C12N2310/3521
摘要: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the CD45 gene.
摘要翻译: 本发明涉及用于抑制CD45基因表达的双链核糖核酸(dsRNA)。
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4.Compositions and methods for inhibiting expression of a gene from the ebola virus 有权
标题翻译: 用于抑制基因从埃博拉病毒表达的组合物和方法公开(公告)号:US07973020B2
公开(公告)日:2011-07-05
申请号:US12789414
申请日:2010-05-27
申请人: Sina Bavari , Kelly Lyn Warfield , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Antonin de Fougerolles
发明人: Sina Bavari , Kelly Lyn Warfield , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Antonin de Fougerolles
CPC分类号: C12N15/1131 , C07H21/02 , C12N2310/14 , C12N2310/315 , C12N2310/321 , C12N2310/322 , C12N2310/3521 , C12N2310/3531
摘要: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a gene from the Ebola virus.
摘要翻译: 本发明涉及用于抑制埃博拉病毒基因表达的双链核糖核酸(dsRNA)。
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5.
公开(公告)号:US20110034537A1
公开(公告)日:2011-02-10
申请号:US12867230
申请日:2009-02-12
申请人: Antonin De Fougerolles , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Sina Bavari , Kelly Lyn Warfield
发明人: Antonin De Fougerolles , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Sina Bavari , Kelly Lyn Warfield
IPC分类号: A61K31/713 , C07H21/02 , C12N5/10 , C12N5/071 , C12N15/63 , A61P37/02 , A61P31/12 , A61P31/16 , A61P31/14
CPC分类号: C12N15/1137 , C12N15/1138 , C12N2310/113 , C12N2310/14 , C12N2310/17 , C12N2310/315 , C12N2310/321 , C12N2310/3515 , C12N2310/3521
摘要: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the CD45 gene.
摘要翻译: 本发明涉及用于抑制CD45基因表达的双链核糖核酸(dsRNA)。
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6.Compositions and methods for inhibiting expression of a gene from the ebola virus 有权
标题翻译: 用于抑制基因从埃博拉病毒表达的组合物和方法公开(公告)号:US08354390B2
公开(公告)日:2013-01-15
申请号:US13093681
申请日:2011-04-25
申请人: Sina Bavari , Kelly Lyn Warfield , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Antonin de Fougerolles
发明人: Sina Bavari , Kelly Lyn Warfield , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Antonin de Fougerolles
CPC分类号: C12N15/1131 , C07H21/02 , C12N2310/14 , C12N2310/315 , C12N2310/321 , C12N2310/322 , C12N2310/3521 , C12N2310/3531
摘要: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a gene from the Ebola virus.
摘要翻译: 本发明涉及用于抑制埃博拉病毒基因表达的双链核糖核酸(dsRNA)。
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7.Compositions And Methods For Inhibiting Expression Of A Gene From The Ebola Virus 有权
标题翻译: 抑制埃博拉病毒基因表达的组合物和方法公开(公告)号:US20110201671A1
公开(公告)日:2011-08-18
申请号:US13093681
申请日:2011-04-25
申请人: Sina Bavari , Kelly Lyn Warfield , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Antonin de Fougerolles
发明人: Sina Bavari , Kelly Lyn Warfield , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Antonin de Fougerolles
IPC分类号: A61K31/713 , C07H21/02 , A61P7/04 , A61P31/00 , A61P11/00 , C12N5/071 , C12N15/63 , C12N5/10
CPC分类号: C12N15/1131 , C07H21/02 , C12N2310/14 , C12N2310/315 , C12N2310/321 , C12N2310/322 , C12N2310/3521 , C12N2310/3531
摘要: The invention relates to a double-stranded ribonucleic acid (dsRNA) FOR INHIBITING THE expression of a gene from the Ebola virus.
摘要翻译: 本发明涉及用于抑制来自埃博拉病毒的基因表达的双链核糖核酸(dsRNA)。
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8.Compositions and methods for inhibiting expression of a gene from the Ebola 失效
标题翻译: 用于抑制基因从埃博拉病毒表达的组合物和方法公开(公告)号:US07759320B2
公开(公告)日:2010-07-20
申请号:US12055295
申请日:2008-03-25
申请人: Sina Bavari , Kelly Lyn Warfield , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Antonin de Fougerolles
发明人: Sina Bavari , Kelly Lyn Warfield , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Antonin de Fougerolles
CPC分类号: C12N15/1131 , C07H21/02 , C12N2310/14 , C12N2310/315 , C12N2310/321 , C12N2310/322 , C12N2310/3521 , C12N2310/3531
摘要: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a gene from the Ebola virus.
摘要翻译: 本发明涉及用于抑制埃博拉病毒基因表达的双链核糖核酸(dsRNA)。
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9.COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF A GENE FROM THE EBOLA 失效
标题翻译: 用于抑制来自EBOLA病毒的基因表达的组合物和方法公开(公告)号:US20090143323A1
公开(公告)日:2009-06-04
申请号:US12055295
申请日:2008-03-25
申请人: Sina Bavari , Kelly Lyn Warfield , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Antonin de Fougerolles
发明人: Sina Bavari , Kelly Lyn Warfield , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Antonin de Fougerolles
IPC分类号: A61K31/713 , C07H21/02 , C12N5/06 , C12N15/63 , C12N5/10
CPC分类号: C12N15/1131 , C07H21/02 , C12N2310/14 , C12N2310/315 , C12N2310/321 , C12N2310/322 , C12N2310/3521 , C12N2310/3531
摘要: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a gene from the Ebola virus.
摘要翻译: 本发明涉及用于抑制埃博拉病毒基因表达的双链核糖核酸(dsRNA)。
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10.
公开(公告)号:US20130065943A1
公开(公告)日:2013-03-14
申请号:US13612521
申请日:2012-09-12
申请人: Antonin De Fougerolles , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Sina Bavari , Kelly Lyn Warfield
发明人: Antonin De Fougerolles , Pamela Tan , Anna Borodovsky , Tatiana Novobrantseva , Sina Bavari , Kelly Lyn Warfield
IPC分类号: C12N15/113 , A61P25/00 , A61P37/00 , C12N15/63 , A61P31/14 , A61P31/20 , C12N5/071 , A61K31/713 , A61P31/16
CPC分类号: C12N15/1137 , C12N15/1138 , C12N2310/113 , C12N2310/14 , C12N2310/17 , C12N2310/315 , C12N2310/321 , C12N2310/3515 , C12N2310/3521
摘要: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the CD45 gene.
摘要翻译: 本发明涉及用于抑制CD45基因表达的双链核糖核酸(dsRNA)。
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