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公开(公告)号：US20090291986A1
公开(公告)日：2009-11-26
申请号：US12125481
申请日：2008-05-22
IPC分类号： A61K31/4436 , A61K31/426 , A61K31/202 , A61P17/02
CPC分类号： A61Q19/08 , A61K8/361 , A61K8/49 , A61K2800/91
摘要： This invention relates to a subcutaneous deliverable composition containing an agonist of the peroxisome proliferator-activated receptor-gamma, and a method for treating facial skin defects in a mammalian subject using the subcutaneous deliverable composition.
摘要翻译： 本发明涉及含有过氧化物酶体增殖物激活受体-γ的激动剂的皮下递送组合物，以及使用皮下递送组合物治疗哺乳动物受试者的面部皮肤缺陷的方法。
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公开(公告)号：US20090291066A1
公开(公告)日：2009-11-26
申请号：US12351942
申请日：2009-01-12
IPC分类号： A61K35/12 , A61K31/4439 , A61K31/426 , A61K31/20 , A61K38/16 , A61K31/715 , A61P17/00
CPC分类号： A61K8/49 , A61K8/97 , A61K31/00 , A61K31/20 , A61K31/426 , A61K31/4439 , A61K31/715 , A61K2800/91 , A61Q19/08
摘要： This invention relates to a subcutaneous deliverable composition containing an agonist of the peroxisome proliferator-activated receptor-gamma, and a method for treating facial skin defects in a mammalian subject using the subcutaneous deliverable composition.
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公开(公告)号：US20070219245A1
公开(公告)日：2007-09-20
申请号：US11685247
申请日：2007-03-13
申请人： Cuifen Hou , Yin Liang , Keith T. Demarest , Druie E. Cavender , Michael P. Wachter , Mingde Xia
发明人： Cuifen Hou , Yin Liang , Keith T. Demarest , Druie E. Cavender , Michael P. Wachter , Mingde Xia
IPC分类号： A61K31/4545
CPC分类号： A61K31/4545
摘要： The present invention is directed to a method for use of substituted dipiperidine compounds of Formula (I) or a salt, isomer, prodrug, metabolite or polymorph thereof, which are CCR2 antagonists, for preventing, treating or ameliorating syndromes, disorders or diseases related to CCR2 activation in a subject in need thereof.
摘要翻译： 本发明涉及一种使用作为CCR2拮抗剂的式（I）的取代二哌啶化合物或其盐，异构体，前药，代谢物或多晶型物，用于预防，治疗或改善综合征，疾病或与 CCR2在有需要的受试者中的活化。
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