公开(公告)号：US20240189333A1

公开(公告)日：2024-06-13

申请号：US18396241

申请日：2023-12-26

申请人： Applaud Medical, Inc.

发明人： Daniel J. LASER ,  Alice LUONG ,  Robert G. MIOTKE

IPC分类号： A61K31/685 ,  A61K9/00 ,  A61K9/16 ,  A61K9/50 ,  A61K41/00 ,  A61K47/06 ,  A61K47/26 ,  A61K47/32 ,  A61K47/54 ,  A61K47/60 ,  A61K47/69 ,  A61P13/04 ,  C07F9/38 ,  C07F9/40

CPC分类号： A61K31/685 ,  A61K9/0034 ,  A61K9/167 ,  A61K9/5015 ,  A61K9/5089 ,  A61K41/0028 ,  A61K47/06 ,  A61K47/26 ,  A61K47/32 ,  A61K47/544 ,  A61K47/60 ,  A61K47/6925 ,  A61P13/04 ,  C07F9/3873 ,  C07F9/405 ,  A61K31/663

摘要： The present disclosure provides phospholipid-containing compounds, pharmaceutical compositions and microspheres that exhibit high affinity for mineralized metals. The present disclosure also provides strategies for using said compounds, compositions and microspheres in the treatment of nephrolithiasis or kidney stone disease, and methods of manufacturing and preparing said compounds and compositions.