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公开(公告)号:US20180064855A1
公开(公告)日:2018-03-08
申请号:US15642968
申请日:2017-07-06
发明人: Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Toby Freyman , Robert J. Caulkins , Quynh P. Pham , Changcheng You , Jeffrey D. Carbeck
IPC分类号: A61L31/06 , A61M37/00 , A61L27/58 , A61B17/12 , A61J1/20 , A61L31/14 , A61L27/56 , A61L27/18
CPC分类号: A61L31/06 , A61B17/12031 , A61B17/12163 , A61B17/12186 , A61B2017/12004 , A61J1/2093 , A61L27/18 , A61L27/56 , A61L27/58 , A61L31/141 , A61L31/146 , A61L31/148 , A61L2400/04 , A61L2400/06 , A61L2400/18 , A61M37/00 , C08L63/00 , C08L67/04
摘要: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
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公开(公告)号:US11207074B2
公开(公告)日:2021-12-28
申请号:US15944154
申请日:2018-04-03
发明人: Gregory T. Zugates , Joseph Lomakin , Jennifer Mortensen , Jeffrey Groom, II , John Marini , Stephanie Webber
摘要: In various aspects, present disclosure is directed to methods, devices and systems whereby one or more low viscosity fluids may be introduced into a catheter and whereby the one or more low viscosity fluids may be converted into a high viscosity fluid in the catheter, which high viscosity fluid may be delivered from an exit port of the catheter.
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公开(公告)号:US10653422B2
公开(公告)日:2020-05-19
申请号:US15729993
申请日:2017-10-11
发明人: Adam Rago , John Marini , Gregory T. Zugates , Marc Helmick , Upma Sharma
摘要: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.
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公开(公告)号:US20180221031A1
公开(公告)日:2018-08-09
申请号:US15944154
申请日:2018-04-03
发明人: Gregory T. Zugates , Joseph Lomakin , Jennifer Mortensen , Jeffrey Groom, II , John Marini , Stephanie Webber
CPC分类号: A61B17/12186 , A61B17/0057 , A61B17/12181 , A61B17/12195 , A61B2017/00495 , A61B2017/00646 , A61B2017/1205 , A61M5/31596 , A61M25/0026
摘要: In various aspects, present disclosure is directed to methods, devices and systems whereby one or more low viscosity fluids may be introduced into a catheter and whereby the one or more low viscosity fluids may be converted into a high viscosity fluid in the catheter, which high viscosity fluid may be delivered from an exit port of the catheter.
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公开(公告)号:US09820749B2
公开(公告)日:2017-11-21
申请号:US14597993
申请日:2015-01-15
发明人: Adam Rago , John Marini , Gregory T. Zugates , Marc Helmick , Upma Sharma
CPC分类号: A61B17/12 , A61B2017/12004 , A61L24/0036 , A61L24/046 , A61L2400/04 , A61M13/003 , A61M2205/3341 , A61M2205/3344 , A61M2210/1021 , A61M2210/12 , C08L75/04
摘要: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.
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公开(公告)号:US10980920B2
公开(公告)日:2021-04-20
申请号:US15923003
申请日:2018-03-16
发明人: Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Robert J. Caulkins , Toby Freyman , Quynh Pham , Changcheng You , Jeffrey Carbeck
IPC分类号: A61F2/02 , A61L31/06 , A61J1/20 , A61L27/18 , A61L27/56 , A61L27/58 , A61L31/14 , A61M37/00 , A61B17/12 , C08L63/00
摘要: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
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公开(公告)号:US20180256774A9
公开(公告)日:2018-09-13
申请号:US15355397
申请日:2016-11-18
发明人: Adam Rago , John Marini , Gregory T. Zugates , Marc Helmick , Upma Sharma
CPC分类号: A61L24/0036 , A61L24/06
摘要: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.
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公开(公告)号:US10052107B2
公开(公告)日:2018-08-21
申请号:US14212930
申请日:2014-03-14
发明人: Rany Busold , John Marini , Upma Sharma , Adam Rago , Jennifer Mortensen , Joseph Lomakin , Gregory T. Zugates , Janet Komatsu , Jeffrey Groom, III
CPC分类号: A61B17/12118 , A61B17/12186 , A61B17/1219 , A61B17/12195 , A61B2017/1205 , A61B2217/005 , A61F2/07 , A61F2/95 , A61F2002/077 , A61M25/0067 , A61M25/007 , A61M25/0074 , A61M25/10 , A61M25/1006 , A61M2025/0004 , A61M2025/0078 , A61M2025/0175
摘要: Systems and method for treating aneurysms are provided which utilize formulations that form polymer foams in situ. The formulations generally have a buoyancy greater than or less than blood, and either float to the top of the aneurysm and foam from the top down or sink to the bottom and foam from the bottom up.
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公开(公告)号:US20180028189A1
公开(公告)日:2018-02-01
申请号:US15729993
申请日:2017-10-11
发明人: Adam Rago , John Marini , Gregory T. Zugates , Marc Helmick , Upma Sharma
CPC分类号: A61B17/12 , A61B2017/12004 , A61L24/0036 , A61L24/046 , A61L2400/04 , A61M13/003 , A61M2205/3341 , A61M2205/3344 , A61M2210/1021 , A61M2210/12 , C08L75/04
摘要: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.
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公开(公告)号:US20160355951A1
公开(公告)日:2016-12-08
申请号:US14603485
申请日:2015-01-23
发明人: Quynh Pham , Xuri Ray Yan , Abby Defeault , Toby Freyman , Joseph Lomakin , Gregory T. Zugates
CPC分类号: D01F8/02 , A61L15/225 , A61L15/28 , D01D5/0038 , D01F1/10 , D01F1/103 , D01F8/10 , D01F8/14 , D01F8/16 , D04H1/425 , D04H1/4382 , D04H1/728 , D04H3/005 , D10B2331/041 , D10B2331/30 , D10B2401/022 , Y10T428/2929 , Y10T442/186
摘要: According to one aspect of the invention, multicomponent fiber comprising (a) a polymeric core that comprises a core-forming polymer and (b) a polymeric sheath that comprises a hydrophilic polymer, wherein the core-forming fiber is more hydrophobic than the hydrophilic polymer and wherein the polymeric core, the polymeric sheath, or both, further comprises a hydrophilic excipient material. Other aspects of the present invention pertain to methods of forming such multicomponent fibers. Still other aspects of the present invention pertain to meshes and other articles that are formed using the multicomponent fibers.
摘要翻译: 根据本发明的一个方面,多组分纤维包含(a)包含成核聚合物的聚合物芯和(b)包含亲水性聚合物的聚合物护套,其中所述成核纤维比亲水性聚合物更疏水 并且其中所述聚合物芯,所述聚合物护套或两者还包含亲水性赋形剂材料。 本发明的其它方面涉及形成这种多组分纤维的方法。 本发明的其它方面涉及使用多组分纤维形成的网格和其它制品。
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