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公开(公告)号：US10814043B2
公开(公告)日：2020-10-27
申请号：US15794086
申请日：2017-10-26
发明人： Keith M. Faucher , Hui Tang , Paul Martakos , Theodore Karwoski , Alison Sullivan , Greg Melville , Scott E. Corbeil
IPC分类号： A61L31/08 , A61L31/16 , A61K31/4353 , A61L31/14 , A61F2/82
摘要： Fatty acid-based, pre-cure-derived biomaterials, methods of making the biomaterials, and methods of using them as drug delivery carriers are described. The fatty acid-derived biomaterials can be utilized alone or in combination with a medical device for the release and local delivery of one or more therapeutic agents. Methods of forming and tailoring the properties of said biomaterials and methods of using said biomaterials for treating injury in a mammal are also provided.
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公开(公告)号：US09827352B2
公开(公告)日：2017-11-28
申请号：US14679368
申请日：2015-04-06
发明人： Keith M. Faucher , Hui Tang , Paul Martakos , Theodore Karwoski , Allison Sullivan , Greg Melville , Scott E. Corbeil
IPC分类号： A61L31/08 , A61K31/4353 , A61L31/16 , A61L31/14 , A61F2/82
CPC分类号： A61L31/08 , A61F2/82 , A61F2250/0067 , A61K31/4353 , A61L31/148 , A61L31/16 , A61L2300/404 , A61L2300/606 , A61L2420/06 , A61L2430/00
摘要： Fatty acid-based, pre-cure-derived biomaterials, methods of making the biomaterials, and methods of using them as drug delivery carriers are described. The fatty acid-derived biomaterials can be utilized alone or in combination with a medical device for the release and local delivery of one or more therapeutic agents. Methods of forming and tailoring the properties of said biomaterials and methods of using said biomaterials for treating injury in a mammal are also provided.
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公开(公告)号：US20130331868A1
公开(公告)日：2013-12-12
申请号：US13833184
申请日：2013-03-15
IPC分类号： A61F2/00
CPC分类号： A61F2/0063 , A61F2/0077 , A61F2002/0072 , F04C2270/0421
摘要： A deployment device for a flexible implant includes a housing and one or two chambers formed therein. When two chambers are included, the housing can have two elongate openings formed in its outer sides, each providing side access to one of the chambers, and the flexible implant can be rolled into a double-rolled configuration and placed in the chambers of the deployment device in such a way that a middle portion of the flexible implant is external to the housing. When the flexible implant is rolled and loaded in the deployment device, the flexible implant can extend out through open end(s) of the chamber(s) or can be encapsulated within the chamber(s). The flexible implant can be provided separate from the deployment device. The flexible implant can include a flexible base sheet including a body portion and a tab. A flexible separable layer can be removably disposed on the body portion.
摘要翻译： 用于柔性植入物的展开装置包括壳体和形成在其中的一个或两个室。 当包括两个室时，壳体可以具有形成在其外侧中的两个细长开口，每个提供侧面进入其中一个室，并且柔性植入物可以卷成双卷构型并放置在展开室中 装置，使得柔性植入物的中间部分在外壳的外部。 当柔性植入物被卷入并装载在展开装置中时，柔性植入物可以延伸穿过室的开口端，或者可以封装在腔室内。 柔性植入物可以与展开装置分开设置。 柔性植入物可以包括柔性基片，其包括主体部分和突片。 柔性可分离层可以可拆卸地设置在主体部分上。
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公开(公告)号：US11793912B2
公开(公告)日：2023-10-24
申请号：US17066466
申请日：2020-10-08
发明人： Keith M. Faucher , Hui Tang , Paul Martakos , Theodore Karwoski , Alison Sullivan , Greg Melville , Scott E. Corbeil
IPC分类号： A61L31/08 , A61L31/16 , A61K31/4353 , A61L31/14 , A61F2/82
CPC分类号： A61L31/08 , A61K31/4353 , A61L31/148 , A61L31/16 , A61F2/82 , A61F2250/0067 , A61L2300/404 , A61L2300/606 , A61L2420/06 , A61L2430/00
摘要： Fatty acid-based, pre-cure-derived biomaterials, methods of making the biomaterials, and methods of using them as drug delivery carriers are described. The fatty acid-derived biomaterials can be utilized alone or in combination with a medical device for the release and local delivery of one or more therapeutic agents. Methods of forming and tailoring the properties of said biomaterials and methods of using said biomaterials for treating injury in a mammal are also provided.
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公开(公告)号：US10219886B2
公开(公告)日：2019-03-05
申请号：US13833184
申请日：2013-03-15
摘要： A deployment device for a flexible implant includes a housing and one or two chambers formed therein. When two chambers are included, the housing can have two elongate openings formed in its outer sides, each providing side access to one of the chambers, and the flexible implant can be rolled into a double-rolled configuration and placed in the chambers of the deployment device in such a way that a middle portion of the flexible implant is external to the housing. When the flexible implant is rolled and loaded in the deployment device, the flexible implant can extend out through open end(s) of the chamber(s) or can be encapsulated within the chamber(s). The flexible implant can be provided separate from the deployment device. The flexible implant can include a flexible base sheet including a body portion and a tab. A flexible separable layer can be removably disposed on the body portion.
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公开(公告)号：US09827353B2
公开(公告)日：2017-11-28
申请号：US14690595
申请日：2015-04-20
发明人： Keith M. Faucher , Hui Tang , Joseph Ferraro , Paul Martakos , Theodore Karwoski , Scott E. Corbeil
IPC分类号： A61L31/08 , A61K31/225 , A61K31/355 , A61L29/08 , A61L29/16 , A61L31/16 , A61L31/14
CPC分类号： A61L31/08 , A61K31/225 , A61K31/355 , A61L29/08 , A61L29/16 , A61L31/148 , A61L31/16 , A61L2300/22
摘要： Fatty acid-derived biomaterials, methods of making the biomaterials, and methods of using them as drug delivery carriers are described. The fatty acid-derived biomaterials can be utilized alone or in combination with a medical device for the release and local delivery of one or more therapeutic agents. Methods of forming and tailoring the properties of said biomaterials and methods of using said biomaterials for treating injury in a mammal are also provided.
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