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公开(公告)号：US20050287214A1
公开(公告)日：2005-12-29
申请号：US11149056
申请日：2005-06-08
申请人： Atul Ayer , Christine Loehrlein , Scott Gilbert , Liang Dong
发明人： Atul Ayer , Christine Loehrlein , Scott Gilbert , Liang Dong
CPC分类号： A61K9/2072 , A61K9/0004 , A61K9/0092 , A61K9/16 , A61K9/2031 , A61K9/2853
摘要： A controlled release dosage form includes an active agent composition and a squeeze layer circumscribing at least a portion of the active agent composition. The squeeze layer includes a material that changes shape in a selected fluid environment of use. The material when it changes shape applies a squeeze force to the active agent composition.
摘要翻译： 控释剂型包括活性剂组合物和限定活性剂组合物的至少一部分的挤压层。 挤压层包括在选定的使用流体环境中改变形状的材料。 当材料改变形状时，材料向活性剂组合物施加挤压力。
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公开(公告)号：US06618679B2
公开(公告)日：2003-09-09
申请号：US09771372
申请日：2001-01-27
申请人： Christine Loehrlein , Dan Pollart , Thomas Shaler , Kathy Stephens , Yuping Tan , Linda Wong , Joseph Monforte
发明人： Christine Loehrlein , Dan Pollart , Thomas Shaler , Kathy Stephens , Yuping Tan , Linda Wong , Joseph Monforte
IPC分类号： G06F1900
CPC分类号： C12Q1/6809 , C12Q1/6853 , C12Q1/686 , G06F19/20 , C12Q2537/143 , C12Q2525/15 , C12Q2525/161 , C12Q2525/155
摘要： This invention provides methods, compositions and kits for gene expression analysis and gene expression profiling. The methods of the invention are highly sensitive; have a wide dynamic range; are rapid and inexpensive; have a high throughput; and allow the simultaneous differential analysis of a defined set of genes. The methods, compositions and kits of the invention also provide tools for gene expression data collection and relational data analysis.
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公开(公告)号：US20090148838A1
公开(公告)日：2009-06-11
申请号：US11978946
申请日：2007-10-29
申请人： Christine Loehrlein , Dan Pollart , Thomas Shaler , Kathy Stephens , Yuping Tan , Linda Wong , Joseph Monforte
发明人： Christine Loehrlein , Dan Pollart , Thomas Shaler , Kathy Stephens , Yuping Tan , Linda Wong , Joseph Monforte
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6809 , C12Q1/6853 , C12Q1/686 , G16B25/00 , C12Q2537/143 , C12Q2525/15 , C12Q2525/161 , C12Q2525/155
摘要： This invention provides methods, compositions and kits for gene expression analysis and gene expression profiling. The methods of the invention are highly sensitive; have a wide dynamic range; are rapid and inexpensive; have a high throughput; and allow the simultaneous differential analysis of a defined set of genes. The methods, compositions and kits of the invention also provide tools for gene expression data collection and relational data analysis.
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