公开(公告)号：US20240361333A1

公开(公告)日：2024-10-31

申请号：US18769201

申请日：2024-07-10

申请人： Autonomous Medical Devices Incorporated

发明人： Ralph Eugene DAVIS ,  Humaira JANWARI ,  Ji Youn LIM ,  Aravind SRINIVASAN ,  David OKRONGLY ,  Sasha PEREBIKOVSKY ,  Brandon POLLACK ,  Marjorie CAPARAS ,  Alex HWU

IPC分类号： G01N33/68 ,  C07K14/005 ,  C12N7/00 ,  G01N33/569

CPC分类号： G01N33/6854 ,  C07K14/005 ,  C12N7/00 ,  G01N33/56983 ,  C12N2770/20022 ,  G01N2333/165

摘要： Disclosed herein are methods, compositions, and devices for the detection of neutralizing antibodies for a pathogen of interest. In some embodiments, a covalent coupling between a viral protein and a receptor protein is utilized to reduce dissociation of the viral protein/receptor complex.