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    DESATURASES AND PROCESS FOR THE PRODUCTION OF POLYUNSATURATED FATTY ACIDS IN TRANSGENIC ORGANISMS
    2.
    发明申请
    DESATURASES AND PROCESS FOR THE PRODUCTION OF POLYUNSATURATED FATTY ACIDS IN TRANSGENIC ORGANISMS 有权
    在转基因生物中生产聚氨酯脂肪酸的苦味和过程

    公开(公告)号：US20140335579A1

    公开(公告)日：2014-11-13

    申请号：US14338673

    申请日：2014-07-23

    Applicant: BASF Plant Science Company GmbH

    Inventor： Toralf Senger ,  Jörg Bauer ,  Johnathan A. Napier

    IPC: C12P7/64 ,  C12N9/02

    CPC classification number: C12P7/6409 ,  C12N9/0071 ,  C12N9/0083 ,  C12N15/8247 ,  C12P7/6427 ,  C12P7/6472 ,  C12P7/6481 ,  C12Y114/19001

    Abstract: The present invention relates to polynucleotides from Cochliobolus heterostrophus C5, Cyanothece sp. CCY0110, Mycocentrospora acerin and Hyaloperonospora parasitica, which code for desaturases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides according to the invention, and to the polypeptides encoded by the polynucleotides. The invention furthermore relates to antibodies against the polypeptides according to the invention. Finally, the invention also relates to production processes for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to their use as drugs, cosmetics, foodstuffs, feedstuffs, preferably fish food, or food supplements.

    Abstract translation: 本发明涉及来自嗜球菌（Cocchioiobolus heterostrophus）C5，蓝藻（Cyanothece sp。）的多核苷酸 CCY0110，真菌孢子菌和寄生藻类，代表去饱和酶，可用于重组生产多不饱和脂肪酸。 本发明还涉及包含根据本发明的多核苷酸的载体，宿主细胞和转基因非人生物以及由多核苷酸编码的多肽。 本发明还涉及针对根据本发明的多肽的抗体。 最后，本发明还涉及多不饱和脂肪酸和油，脂和脂肪酸组合物的生产方法以及它们作为药物，化妆品，食品，饲料，优选鱼食或食品添加剂的用途。

    Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms
    3.
    发明授权
    Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms 有权
    去饱和酶和在转基因生物体内生产多不饱和脂肪酸的方法

    公开(公告)号：US09139854B2

    公开(公告)日：2015-09-22

    申请号：US14338673

    申请日：2014-07-23

    Applicant: BASF Plant Science Company GmbH

    Inventor： Toralf Senger ,  Jörg Bauer ,  Johnathan A. Napier

    IPC: C12P7/64 ,  C12N9/02 ,  C07H21/02 ,  C12N15/82

    CPC classification number: C12P7/6409 ,  C12N9/0071 ,  C12N9/0083 ,  C12N15/8247 ,  C12P7/6427 ,  C12P7/6472 ,  C12P7/6481 ,  C12Y114/19001

    Abstract: The present invention relates to polynucleotides from Cochliobolus heterostrophus C5, Cyanothece sp. CCY0110, Mycocentrospora acerin and Hyaloperonospora parasitica, which code for desaturases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides according to the invention, and to the polypeptides encoded by the polynucleotides. The invention furthermore relates to antibodies against the polypeptides according to the invention. Finally, the invention also relates to production processes for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to their use as drugs, cosmetics, foodstuffs, feedstuffs, preferably fish food, or food supplements.

    Abstract translation: 本发明涉及来自嗜球菌（Cocchioiobolus heterostrophus）C5，蓝藻（Cyanothece sp。）的多核苷酸 CCY0110，真菌孢子菌和寄生藻类，代表去饱和酶，可用于重组生产多不饱和脂肪酸。 本发明还涉及包含根据本发明的多核苷酸的载体，宿主细胞和转基因非人生物以及由多核苷酸编码的多肽。 本发明还涉及针对根据本发明的多肽的抗体。 最后，本发明还涉及多不饱和脂肪酸和油，脂和脂肪酸组合物的生产方法以及它们作为药物，化妆品，食品，饲料，优选鱼食或食品添加剂的用途。

    NOVEL FATTY ACID DESATURASES AND ELONGASES AND USES THEREOF
    7.
    发明申请
    NOVEL FATTY ACID DESATURASES AND ELONGASES AND USES THEREOF 审中-公开
    新型脂肪酸及其用途及其用途

    公开(公告)号：US20170067070A1

    公开(公告)日：2017-03-09

    申请号：US15351962

    申请日：2016-11-15

    Applicant: BASF Plant Science Company GmbH

    Inventor： Jörg Bauer ,  Johnathan A. Napier ,  Olga Sayanova

    IPC: C12N15/82 ,  C12N9/00 ,  C12N9/02

    CPC classification number: C12N15/8247 ,  C07K14/435 ,  C12N9/0071 ,  C12N9/93 ,  C12Y114/19 ,  C12Y114/19003 ,  C12Y114/19004 ,  C12Y114/19006 ,  C12Y602/01003

    Abstract: The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g. arachidonic acid (ARA), eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA).

    Abstract translation: 本发明提供了分离的核酸分子，其编码来自生物Emiliana huxleyi的新型脂肪酸去饱和酶和延伸酶。 本发明还提供了含有去饱和酶或延伸酶核酸分子的重组表达载体，已引入表达载体的宿主细胞，以及用于大规模生产长链多不饱和脂肪酸（LCPUFA）的方法。 花生四烯酸（ARA），二十碳五烯酸（EPA）或二十二碳六烯酸（DHA）。

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