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1.发明授权Use of polyether-based and vinyl monomer-based copolymers as binders for dosing forms comprising solid active ingredients 有权使用聚醚基和乙烯基单体基共聚物作为包含固体活性成分的剂型的粘合剂公开(公告)号：US09439971B2
公开(公告)日：2016-09-13
申请号：US13732833
申请日：2013-01-02
Applicant: BASF SE
Inventor： Kathrin Meyer-Böhm , Rainer Dobrawa , Angelika Maschke , Karl Kolter
CPC classification number: A61K47/34 , A61K9/1641 , A61K9/2031 , A61K9/2095
Abstract: The use of water-soluble or water-dispersible copolymers which are obtained by free radical-initiated polymerization of a mixture of i) 30 to 80% by weight N-vinyllactam, ii) 10 to 50% by weight vinylacetate and iii) 10 to 50% by weight of a polyether, with the proviso that the total of i), ii) and iii) is equal to 100% by weight, as binders for producing solid active ingredient-containing dosage forms.
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2.发明申请Use Of Polyether-Based And Vinyl Monomer-Based Copolymers As Binders For Dosing Forms Comprising Solid Active Ingredients 审中-公开使用基于聚醚和乙烯基单体的共聚物作为包含固体活性成分的剂型的粘合剂公开(公告)号：US20130123373A1
公开(公告)日：2013-05-16
申请号：US13732833
申请日：2013-01-02
Applicant: BASF SE
Inventor： Kathrin Meyer-Böhm , Rainer Dobrawa , Angelika Maschke , Karl Kolter
CPC classification number: A61K47/34 , A61K9/1641 , A61K9/2031 , A61K9/2095
Abstract: The use of water-soluble or water-dispersible copolymers which are obtained by free radical-initiated polymerization of a mixture of i) 30 to 80% by weight N-vinyllactam, ii) 10 to 50% by weight vinylacetate and iii) 10 to 50% by weight of a polyether, with the proviso that the total of i), ii) and iii) is equal to 100% by weight, as binders for producing solid active ingredient-containing dosage forms.
Abstract translation: 使用水溶性或水分散性共聚物，其通过i）30至80重量％的N-乙烯基内酰胺的混合物的自由基引发聚合获得，ii）10至50重量％的乙酸乙烯酯和iii）10至 50重量％的聚醚，条件是i），ii）和iii）的总量等于100重量％，作为用于生产含固体活性成分的剂型的粘合剂。
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3.发明申请公开(公告)号：US20130084338A1
公开(公告)日：2013-04-04
申请号：US13632335
申请日：2012-10-01
Applicant: BASF SE
Inventor： Angelika Maschke , Karl Kolter , Kathrin Meyer-Böhm , Thorsten Schmeller
CPC classification number: A61K9/1611 , A61K9/1635 , A61K9/2077 , A61K9/5026
Abstract: Method for producing pigment-containing granules for pharmaceutical applications based on film-forming enteric polymers, wherein the production of the granules takes place by a spraying process in which the enteric polymeric film formers are introduced as initial charge in a fluidized bed, and an aqueous pigment suspension, which comprises a plasticizer that is solid at 20° C., is sprayed onto the fluidized bed.
Abstract translation: 用于制备基于成膜肠溶性聚合物的用于药物应用的含颜料的颗粒的方法，其中所述颗粒的生产通过喷雾方法进行，其中肠溶性聚合物成膜剂在流化床中作为初始装料引入， 将包含在20℃下为固体的增塑剂的颜料悬浮液喷雾到流化床上。
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