Method of removing DNA from biotechnological products

    公开(公告)号:US10301588B2

    公开(公告)日:2019-05-28

    申请号:US15533432

    申请日:2015-12-09

    申请人: BASF SE

    摘要: The present invention relates to a method for degrading DNA in a sample obtained by microbial fermentation or biotransformation, comprising treating the sample with a combination of increased temperature and low pH. It also relates to a method for releasing DNA from a microbial cell, comprising incubating the microbial cell at a temperature of 45° C. to 55° C. for two to ten hours. Finally, the present invention provides a method for producing a product, comprising a step of releasing DNA from a microbial cell and degrading said DNA.