公开(公告)号：US20160340666A1

公开(公告)日：2016-11-24

申请号：US15234529

申请日：2016-08-11

Applicant: BASF SE

Inventor： Michael Breuer ,  Bernhard Hauer ,  Dieter Jendrossek ,  Gabrielle Siedenburg ,  Juergen Pleiss ,  Demet Sirim ,  Silivia Fadenrecht

IPC: C12N9/88 ,  C12P7/22 ,  C12P5/00

CPC classification number: C12N9/88 ,  C12N9/90 ,  C12P5/007 ,  C12P7/02 ,  C12P7/22 ,  C12Y406/01 ,  C12Y504/99017 ,  Y02P20/52

Abstract: The present invention relates to novel mutants with cyclase activity and use thereof in a method for biocatalytic cyclization of terpenes, such as in particular for the production of isopulegol by cyclization of citronellal; a method for the preparation of menthol and methods for the biocatalytic conversion of further compounds with structural motifs similar to terpene.