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1.发明申请Active-Ingredient-Containing Solid Dispersions Based on Diethylaminoethyl Methacrylate Copolymers 审中-公开基于甲基丙烯酸二乙基氨基乙酯共聚物的含活性成分的固体分散体公开(公告)号：US20130345320A1
公开(公告)日：2013-12-26
申请号：US13919092
申请日：2013-06-17
Applicant: BASF SE
Inventor： Karl Kolter , Maximilian Angel , Matthias Karl , Silke Gebert , Michael Klemens Müller
IPC: A61K47/32
CPC classification number: A61K47/32 , A61K9/146 , A61K9/1635
Abstract: Described are solid dispersions of hydrophobic active ingredients and cationic copolymers of N,N-diethylaminoethyl methacrylate and methyl methacrylate in a weight ratio of the monomers of from 35:65 to 55:45. Also described are the preparation and use of such solid dispersions for pharmaceutical dosage forms.
Abstract translation: 描述了单体重量比为35:65至55:45的疏水性活性成分和甲基丙烯酸N，N-二乙基氨基乙酯和甲基丙烯酸甲酯的阳离子共聚物的固体分散体。 还描述了用于药物剂型的这种固体分散体的制备和用途。
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2.发明申请Production Of Pharmaceutical Protective Coatings With Good Resistance In A Neutral Environment 审中-公开在中性环境中生产具有良好电阻的药用保护涂料公开(公告)号：US20130236505A1
公开(公告)日：2013-09-12
申请号：US13790101
申请日：2013-03-08
Applicant: BASF SE
Inventor： Karl Kolter , Silke Gebert , Michael Klemens Müller , Maximilian Angel
CPC classification number: A61K47/32 , A61K9/0002 , A61K9/282 , A61K9/2846 , A61K9/5015 , A61K9/5026 , A61K47/12
Abstract: Pharmaceutical coatings obtained from coating compositions based on film-forming copolymers of N,N-diethylaminoethyl methacrylate (DEAEMA) and methyl methacrylate (MMA) comprising a weight ratio of DEAEMA:MMA in the range of 35:65 to 55:45, where the copolymers are present partially neutralized with C3-C10-dicarboxylic acids.
Abstract translation: 由基于N，N-二乙基氨基乙基甲基丙烯酸酯（DEAEMA）和甲基丙烯酸甲酯（MMA）的成膜共聚物的涂料组合物获得的药物涂料，其重量比为DEAEMA:MMA，范围为35:65至55:45，其中 共聚物用C3-C10-二羧酸部分中和。
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公开(公告)号：US20240350414A1
公开(公告)日：2024-10-24
申请号：US18684728
申请日：2022-08-19
Applicant: BASF SE
Inventor： Silke Gebert , Felicitas Guth , Thorsten Cech , Karl Kolter
IPC: A61K9/20 , A61K31/192 , A61K31/451
CPC classification number: A61K9/2031 , A61K9/2013 , A61K9/2018 , A61K9/2027 , A61K31/192 , A61K31/451
Abstract: The present invention relates to a direct tableting auxiliary composition based on lactose powder mixed intimately with a water-soluble polyethylene glycol-polyvinyl alcohol graft copolymeras binder, crosslinked insoluble polyvinylpyrrolidone as tablet disintegrating agent and a lubricant.
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Patent Agency Ranking
公开(公告)号：US11154508B2
公开(公告)日：2021-10-26
申请号：US16624332
申请日：2018-06-05
Applicant: BASF SE
Inventor： Bernhard Fussnegger , Silke Gebert , Felicitas Guth , Karl Kolter
Abstract: A finely divided binder in powder form consisting of a polyethylene glycol-polyvinyl alcohol graft polymer particles, wherein the particles have an average particle size D[4,3] in the range of from 10 to 70 μm.
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5.发明授权公开(公告)号：US10912835B2
公开(公告)日：2021-02-09
申请号：US15848124
申请日：2017-12-20
Applicant: BASF SE
Inventor： Karl Kolter , Silke Gebert , Michael Klemens Müller , Maximilian Angel
Abstract: Pharmaceutical coatings obtained from coating compositions based on film-forming copolymers of N,N-diethylaminoethyl methacrylate (DEAEMA) and methyl methacrylate (MMA) comprising a weight ratio of DEAEMA:MMA in the range of 35:65 to 55:45, where the copolymers are present partially neutralized with C3-C10-dicarboxylic acids.
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6.发明申请公开(公告)号：US20180110858A1
公开(公告)日：2018-04-26
申请号：US15848124
申请日：2017-12-20
Applicant: BASF SE
Inventor： Karl Kolter , Silke Gebert , Michael Klemens Müller , Maximilian Angel
CPC classification number: A61K47/32 , A61K9/0002 , A61K9/282 , A61K9/2846 , A61K9/5015 , A61K9/5026 , A61K47/12
Abstract: Pharmaceutical coatings obtained from coating compositions based on film-forming copolymers of N,N-diethylaminoethyl methacrylate (DEAEMA) and methyl methacrylate (MMA) comprising a weight ratio of DEAEMA:MMA in the range of 35:65 to 55:45, where the copolymers are present partially neutralized with C3-C10-dicarboxylic acids.
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公开(公告)号：US20250017861A1
公开(公告)日：2025-01-16
申请号：US18714342
申请日：2022-11-30
Applicant: BASF SE
Inventor： Silke Gebert , Felicitas Guth , Claudia Scholten , Thorsten Cech , Florian Bang
IPC: A61K9/16
Abstract: The present invention relates to a direct tableting auxiliary composition based on lactose powder mixed intimately with a water-soluble polyethylene glycol-polyvinyl alcohol graft copolymeras binder, a lubricants, a colorant and optionally a crosslinked insoluble polyvinylpyrrolidone as tablet disintegrating agent.
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8.发明授权公开(公告)号：US10668156B2
公开(公告)日：2020-06-02
申请号：US13919092
申请日：2013-06-17
Applicant: BASF SE
Inventor： Karl Kolter , Maximilian Angel , Matthias Karl , Silke Gebert , Michael Klemens Mueller
Abstract: Described are solid dispersions of hydrophobic active ingredients and cationic copolymers of N,N-diethylaminoethyl methacrylate and methyl methacrylate in a weight ratio of the monomers of from 35:65 to 55:45. Also described are the preparation and use of such solid dispersions for pharmaceutical dosage forms.
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