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公开(公告)号：US20230065510A1
公开(公告)日：2023-03-02
申请号：US17984714
申请日：2022-11-10
发明人： Eric C. Meyers , Gaurav Sharma , Samuel Colachis , Nicholas J. Tacca , Philip T. Putnam , Michael Darrow , Bryan R. Schlink
摘要： A therapeutic or diagnostic device comprises a wearable electrodes garment including electrodes disposed to contact skin when the wearable electrodes garment is worn, and an electronic controller operatively connected with the electrodes. The electronic controller is programmed to perform a method including: receiving surface electromyography (EMG) signals via the electrodes and extracting one or more motor unit (MU) action potentials from the surface EMG signals. The method may further include identifying an intended movement based at least on features representing the one or more extracted MU action potentials and delivering functional electrical stimulation (FES) effective to implement the intended movement via the electrodes of the wearable electrodes garment. The method may further include generating a patient performance report based at least on a comparison of features representing the one or more extracted MU action potentials and features representing expected and/or baseline MU action potentials for a known intended movement.
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公开(公告)号：US11583676B2
公开(公告)日：2023-02-21
申请号：US17081450
申请日：2020-10-27
IPC分类号： A61N1/36 , A61B5/00 , A61B5/11 , A61N1/05 , A61B5/375 , A61F2/72 , A61F4/00 , A61G5/00 , A61H3/00 , A61B5/16
摘要： The present disclosure relates generally to systems, methods, and devices for interpreting neural signals to determine a desired movement of a target, transmitting electrical signals to the target, and dynamically monitoring subsequent neural signals or movement of the target to change the signal being delivered if necessary, so that the desired movement is achieved. In particular, the neural signals are decoded using a feature extractor, decoder(s) and a body state observer to determine the electrical signals that should be sent.
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公开(公告)号：US11426495B2
公开(公告)日：2022-08-30
申请号：US16996229
申请日：2020-08-18
摘要： A chronically implanted medical device is disclosed that has an outermost layer formed from a conjugate of a polymer with lipoic acid, the conjugate having free 1,2-dithiolane groups. It is contemplated that this layer scavenges reactive oxygen species, i.e. acts as an antioxidant, and thus reduces inflammation and other adverse effects around the implant itself.
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公开(公告)号：US10857358B2
公开(公告)日：2020-12-08
申请号：US15578776
申请日：2016-06-02
IPC分类号： A61B5/00 , A61N1/36 , A61B5/0482 , A61B5/11 , A61N1/05 , A61F2/72 , A61F4/00 , A61G5/00 , A61H3/00 , A61B5/16
摘要： The present disclosure relates generally to systems, methods, and devices for interpreting neural signals to determine a desired movement of a target, transmitting electrical signals to the target, and dynamically monitoring subsequent neural signals or movement of the target to change the signal being delivered if necessary, so that the desired movement is achieved. In particular, the neural signals are decoded using a feature extractor, decoder(s) and a body state observer to determine the electrical signals that should be sent.
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公开(公告)号：US20200078496A1
公开(公告)日：2020-03-12
申请号：US16682987
申请日：2019-11-13
摘要： A chronically implanted medical device is disclosed that has an outermost layer formed from a conjugate of a polymer with lipoic acid, the conjugate having free 1,2-dithiolane groups. It is contemplated that this layer scavenges reactive oxygen species, i.e. acts as an antioxidant, and thus reduces inflammation and other adverse effects around the implant itself.
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公开(公告)号：US20160250392A1
公开(公告)日：2016-09-01
申请号：US15053532
申请日：2016-02-25
CPC分类号： A61L31/10 , A61L2400/18 , A61N1/0536 , C08L33/08
摘要： A chronically implanted medical device is disclosed that has an outermost layer formed from a conjugate of a polymer with lipoic acid, the conjugate having free 1,2-dithiolane groups. It is contemplated that this layer scavenges reactive oxygen species, i.e. acts as an antioxidant, and thus reduces inflammation and other adverse effects around the implant itself.
摘要翻译： 公开了一种长期植入的医疗装置，其具有由聚合物与硫辛酸的共轭物形成的最外层，该缀合物具有游离的1,2-二硫戊环基团。 预期该层清除活性氧物质，即作为抗氧化剂，从而减少植入物本身周围的炎症和其它不利影响。
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公开(公告)号：US20230271007A1
公开(公告)日：2023-08-31
申请号：US18108095
申请日：2023-02-10
CPC分类号： A61N1/36031 , A61N1/025 , A61N1/36003 , G06N3/02
摘要： At least one electrical brain signal is received from a patient and is demultiplexed into an efferent motor intention signal and at least one afferent sensory signal (such as an afferent touch sense signal and/or an afferent proprioception signal). A functional electrical stimulation (FES) device is controlled to apply FES to control a paralyzed portion of the patient that is paralyzed due to a spinal cord injury of the patient. The controlling of the FES device is based on at least the efferent motor intention signal. A demultiplexed afferent touch sense signal may be used to control a haptic device. The afferent sensory signal(s) may be used to adjust the FES control.
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公开(公告)号：US11524160B2
公开(公告)日：2022-12-13
申请号：US16913706
申请日：2020-06-26
发明人： Gaurav Sharma , Samuel Colachis
摘要： A therapeutic or diagnostic device comprises a wearable electrodes garment including electrodes disposed to contact skin when the wearable electrodes garment is worn, and an electronic controller operatively connected with the electrodes. The electronic controller is programmed to perform a method including: receiving surface electromyography (EMG) signals via the electrodes and extracting one or more motor unit (MU) action potentials from the surface EMG signals. The method may further include identifying an intended movement based at least on features representing the one or more extracted MU action potentials and delivering functional electrical stimulation (FES) effective to implement the intended movement via the electrodes of the wearable electrodes garment. The method may further include generating a patient performance report based at least on a comparison of features representing the one or more extracted MU action potentials and features representing expected and/or baseline MU action potentials for a known intended movement.
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公开(公告)号：US20220001164A1
公开(公告)日：2022-01-06
申请号：US17476723
申请日：2021-09-16
发明人： Gaurav Sharma , Patrick Ganzer
摘要： A tremor suppression device includes a garment wearable on an anatomical region and including electrodes contacting the anatomical region when the garment is worn on the anatomical region, and an electronic controller configured to: detect electromyography (EMG) signals as a function of anatomical location and time using the electrodes; identify tremors as a function of anatomical location and time based on the EMG signals; and apply neuromuscular electrical stimulation (NMES) at one or more anatomical locations as a function of time using the electrodes to suppress the identified tremors.
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公开(公告)号：US20210379372A1
公开(公告)日：2021-12-09
申请号：US17339309
申请日：2021-06-04
摘要： A portable and wearable hand-grasp neuro-orthosis is configured for use in a home environment to restore volitionally controlled grasp functions for a subject with a cervical spinal cord injury (SCI). The neuro-orthosis may include: a wearable sleeve with electrodes; electronics for operating the wearable sleeve to perform functional electrical stimulation (FES) and electromyography (EMG), the electronics configured for mounting on a wheelchair; and a controller configured for mounting on a wheelchair. The controller controls the electronics to read EMG via the sleeve, decode the read EMG to determine an intent of the user, and operate the electronics to apply FES via the sleeve to implement the intent of the user. The neuro-orthosis may restore hand function. The controller may include a display arranged to be viewed by the subject, for example mounted on an articulated arm attached to the wheelchair.
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