公开(公告)号：US20160280648A1

公开(公告)日：2016-09-29

申请号：US15033987

申请日：2014-11-11

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Wahed Ahmed MORADI ,  Thomas HIMMLER ,  Thomas Norbert MUELLER ,  Albert SCHNATTERER ,  Guenter SCHLEGEL

IPC: C07D213/56

CPC classification number: C07D213/56 ,  C07D213/38 ,  C07D213/57 ,  C07D213/89

Abstract: The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluorometyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluorometyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of metal catalysts, in particular palladium catalysts.

Abstract translation: 本发明涉及取代的2-甲基氰基吡啶衍生物，特别是3-氯-5-（三氟甲基）吡啶-2-基]乙腈[= Py-CN]到取代的2-乙基氨基吡啶衍生物的催化氢化，特别是 2- [3-氯-5-（三氟甲基）吡啶-2-基]乙胺[= Py-乙胺]或其盐在金属催化剂，特别是钯催化剂存在下。

公开(公告)号：US20170313730A1

公开(公告)日：2017-11-02

申请号：US15655271

申请日：2017-07-20

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Hans-Joachim RESSEL ,  Kilian TELLMAN ,  Mark James FORD ,  Martin LITTMANN ,  Friedrich August MUEHLTHAU ,  Guenter SCHLEGEL

IPC: C07F9/32 ,  C07F9/30

CPC classification number: C07F9/3211 ,  C07F9/301

Abstract: The present invention relates primarily to a process for preparing certain phosphorus-containing cyanohydrins of the formula (I), and also to certain phosphorus-containing cyanohydrins per se and to their use for the preparation of glufosinate and/or glufosinate salts. The present invention further relates to certain mixtures particularly suitable for preparing the phosphorus-containing cyanohydrins of the formula (I).

公开(公告)号：US20170081349A1

公开(公告)日：2017-03-23

申请号：US15310566

申请日：2015-05-08

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Hans-Joachim RESSEL ,  Kilian TELLMAN ,  Mark James FORD ,  Martin LITTMANN ,  Friedrich August MUEHLTHAU ,  Guenter SCHLEGEL

IPC: C07F9/32 ,  C07F9/30

CPC classification number: C07F9/3211 ,  C07F9/301

Abstract: The present invention relates primarily to a process for preparing certain phosphorus-containing cyanohydrins of the formula (I), and also to certain phosphorus-containing cyanohydrins per se and to their use for the preparation of glufosinate and/or glufosinate salts. The present invention further relates to certain mixtures particularly suitable for preparing the phosphorus-containing cyanohydrins of the formula (I).

公开(公告)号：US20170081284A1

公开(公告)日：2017-03-23

申请号：US15126593

申请日：2015-03-18

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Wahed Ahmed MORADI ,  Guenter SCHLEGEL ,  Albert SCHNATTERER

IPC: C07D213/38

CPC classification number: C07D213/38 ,  C07D213/61

Abstract: A process for preparing N-[(6-chloropyridin-3-yl)methyl]-2,2-difluoroethan-1-amine of formula (III) wherein 2,2-difluoroethylamine of formula (I) is reacted with a halide of formula (II) in the presence of a hydroxide of an alkali metal or alkaline earth metal.