公开(公告)号：US20160280648A1

公开(公告)日：2016-09-29

申请号：US15033987

申请日：2014-11-11

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Wahed Ahmed MORADI ,  Thomas HIMMLER ,  Thomas Norbert MUELLER ,  Albert SCHNATTERER ,  Guenter SCHLEGEL

IPC: C07D213/56

CPC classification number: C07D213/56 ,  C07D213/38 ,  C07D213/57 ,  C07D213/89

Abstract: The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluorometyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluorometyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of metal catalysts, in particular palladium catalysts.

Abstract translation: 本发明涉及取代的2-甲基氰基吡啶衍生物，特别是3-氯-5-（三氟甲基）吡啶-2-基]乙腈[= Py-CN]到取代的2-乙基氨基吡啶衍生物的催化氢化，特别是 2- [3-氯-5-（三氟甲基）吡啶-2-基]乙胺[= Py-乙胺]或其盐在金属催化剂，特别是钯催化剂存在下。

公开(公告)号：US20200039936A1

公开(公告)日：2020-02-06

申请号：US16471144

申请日：2017-12-18

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Wahed Ahmed MORADI ,  Thomas HIMMLER ,  Thomas Norbert MUELLER

IPC: C07D213/26 ,  C07D213/40

Abstract: The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of Raney catalysts, in particular Raney nickel or cobalt.

公开(公告)号：US20190023633A1

公开(公告)日：2019-01-24

申请号：US16070244

申请日：2017-01-09

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Thomas HIMMLER ,  Peter BRÜCHNER

IPC: C07C29/36 ,  C07C33/20 ,  C07C33/46

CPC classification number: C07C29/36 ,  C07C33/20 ,  C07C33/46 ,  C07C43/23

Abstract: The invention relates to a process for preparing substituted 2-arylethanols of the formula (I) by reacting Grignard compounds of the formula (II) in the presence of a copper compound with ethylene oxide. Moreover, the invention relates to novel substituted 2-arylethanols of the formula (I).

公开(公告)号：US20180305302A1

公开(公告)日：2018-10-25

申请号：US15769765

申请日：2016-10-21

Applicant: Bayer CropScience Aktiengesellschaft

Inventor： Christian FUNKE ,  Thomas HIMMLER ,  Sergii PAZENOK ,  Christoph SCHOTES ,  Matthias BELLER ,  Thomas SCHAREINA ,  Alexander ZAPF

IPC: C07C253/14 ,  C07C319/14 ,  C07C319/20 ,  C07C315/02 ,  C07C25/13 ,  C07C255/50 ,  C07C323/36

CPC classification number: C07C253/14 ,  C07C25/13 ,  C07C255/50 ,  C07C315/02 ,  C07C319/14 ,  C07C319/20 ,  C07C323/36 ,  C07C323/62 ,  C07C317/44

Abstract: A process for preparing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids of the formula (I) is described. Here, the substituents are radicals such as alkyl and substituted phenyl.

公开(公告)号：US20190202837A1

公开(公告)日：2019-07-04

申请号：US16322556

申请日：2017-07-31

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Thomas HIMMLER ,  Julia Johanna HAHN ,  Joachim CREDE

IPC: C07D491/113 ,  C07D317/72 ,  C07D319/08 ,  C07D407/12

CPC classification number: C07D491/113 ,  A01N43/90 ,  C07D317/72 ,  C07D319/08 ,  C07D407/12

Abstract: The invention relates to a novel process for preparing spiroketal-substituted cyclic ketoenols which can be used as insecticides, acaricides or herbicides. The present invention also relates to novel intermediates for the preparation of spiroketal-substituted cyclic ketoenols.

公开(公告)号：US20190039995A1

公开(公告)日：2019-02-07

申请号：US16074639

申请日：2017-01-27

Applicant: Bayer CropScience Aktiengesellschaft

Inventor： Christoph SÄMANN ,  Thomas HIMMLER

IPC: C07C209/68

Abstract: The present invention relates to a method for preparing substituted 4-aminoindane derivatives of the general formula (I) by cyclization, in which R, n, R1, R2, R3, R4, Q1 and Q2 have the definitions specified in the description.

公开(公告)号：US20180362446A1

公开(公告)日：2018-12-20

申请号：US16113624

申请日：2018-08-27

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Thomas HIMMLER ,  Lars RODEFELD ,  Jonathan HUBRICH ,  Lutz ACKERMANN

IPC: C07C231/12 ,  C07C233/15 ,  C07C233/25 ,  C07C233/29 ,  C07C233/66 ,  C07C233/75

CPC classification number: C07C231/12 ,  C07C233/15 ,  C07C233/25 ,  C07C233/75 ,  C07C233/66 ,  C07C233/29

Abstract: The present invention relates to a novel process for preparing substituted biphenylamides of the general formula (V) characterized in that anilides of the formula (II) in a solvent other than tetrahydrofuran, are reacted with an organoboron compound of the formula (III) in the presence of a catalyst system consisting of a ruthenium catalyst, an activator, an oxidizing agent and a metal triflate.