Abstract:
The present invention relates to a novel process for preparing substituted biphenylamides of the general formula (V) characterized in that anilides of the formula (II) in a solvent other than tetrahydrofuran, are reacted with an organoboron compound of the formula (III) in the presence of a catalyst system consisting of a ruthenium catalyst, an activator, an oxidizing agent and a metal triflate.
Abstract:
The present invention relates to a process for preparing substituted biphenylanilides of the formula (I) in which R1 is selected from a protected amino group, NO2, NH2 and NHR3, in which a compound of the formula II is reacted in the presence of a base and of a palladium salt, in the presence of a phosphine ligand of the formula (V) as complex ligand or a salt thereof, in a solvent, with an organoboron compound of the formula (III) in which all the substituents are as defined in the description.